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Effects of tobacco use on non-adherence to antiretroviral therapy among HIV-positive patients in South Africa
Authors:Supa Pengpid  Diana Huis in ‘t Veld
Institution:1. ASEAN Institute for Health Development, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom, Thailand;2. Office of the Deputy Vice Chancellor, Research and Innovation, North West University, Potchestroom, South Africa;3. Department of Internal Medicine and Infectious Diseases, UZ Ghent, Gent, Belgium;4. Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium;5. FWO Research Foundation Flanders, Brussels, Belgium
Abstract:This study aimed to estimate the relationship between tobacco use and non-adherence to antiretroviral therapy (ART) in a South African sample. Participants were 1 963 HIV patients who attended a primary care clinic in Pretoria (female = 68.5%; black African = 99.5%; median age = 37.0 years; tobacco users only = 8.6%, problem drinkers only = 14.9%, and tobacco users and problem drinkers = 10.5%). In adjusted logistic regression analysis, tobacco use only was not significantly associated with non-adherence to ART. Alcohol use only (OR: 1.72; CI: 1.26, 2.36) and tobacco use and problem drinking (OR: 2.31; CI: 1.60, 3.33) were highly associated with non-adherence to ART.
Keywords:adherence  antiretroviral therapy  problem drinking  South Africa  tobacco use
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