Behavioral effects of stimulation of the medial amygdala in the male rat are modified by prior sexual experience

Researchers have found that stimulation of the medial nucleus of the amygdala (MeA) in male rats increases appetitive copulatory behavior directed toward an anestrous female but suppresses copulation with an estrous female (C. P. Stark et al., 1998). The objective in the present study was to determine if the behavioral change produced by stimulation of the MeA was dependent on chemical and/or visual cues from the conspecific. The author reports that electrical stimulation of the MeA in male rats increased the frequency of mounting and investigative behavior directed toward a male conspecific. However, these effects were limited to those subjects that had no prior sexual experience. Results are discussed in terms of possible experience-dependent alterations in neural response patterns within the MeA and related areas.