MRI对儿童难治性、局灶性癫痫的临床诊断及预后判断

癫痫外科的临床病理研究表明,儿童局灶性皮质发育不良(FCD)及海马硬化是儿童难治性局灶性癫痫常见的致病因素。但在术前的常规的MRI检查中,这些结构上的异常经常被忽视,从而造成延误诊断。临床医生在阅片判断上的失误可能是一个原因,但癫痫的影像专业知识的不全面是重要因素。本文结合MRI技术在癫痫临床诊断领域的应用进展,阐述了儿童难治性、局灶性癫痫患者MRI影像中可能出现的结构性病变;重点阐述了临床易于忽视的局灶性皮质发育不良(FCD)及海马硬化的MRI研究、应用进展。

The Application of MRI in Diagnosis and Prognosis of Children with Refractory Focal Epilepsy

The pathologic finds proved that the focal cortical dysplasia and Hippocampal sclerosis are frequent pathogenic factors for children refractory focal epilepsy. But they are always be overlooked on standard MRI scan during the normal diagnosis procedure. Errors in the interpretation of MRI of epilepsy patient can be attributed to incomplete knowledge and poor judgment of the clinic doctors. This review covers the MRI technology advance in the field of clinical diagnosis of epilepsy, and discusses the MRI character of the children with intractable, focal seizures may,focuses on the focal cortical dysplasia neglect （FCD） and hippocampal sclerosis in MRI research, which were very be easily overlooked.