流式细胞术在骨髓增生异常综合征及再生障碍性贫血诊断中的应用

为探讨骨髓增生异常综合征患者与再生障碍性贫血患者骨髓髓系细胞的免疫表型变化，用流式细胞术检测骨髓增生异常综合征、再生障碍性贫血及正常对照髓系细胞的表面抗原。结果显示骨髓增生异常综合征组髓系细胞较正常对照组及再生障碍性贫血组表面抗原表达明显不同。因此，流式细胞术有助于二者的诊断及鉴别诊断。

The Importance of the Connotation of Medical Records from Health Insurance Point of View

To explore the immunophenotype of myeloid granulocytes in myelodsplastic syndromes （MDS） and aplastic anemia （AA）, we detected CD13、CD33、CD15、CD10、CD34 and HLA-DR on the membrane surface of myeloid granulocytes from patients with myelodysplastic syndromes, patients with aplastic anemia and normal subjects by flow cytometry. There was an immunophenotypic misexpression of myeloid granuloeytes in MDS patients. So the immunophenotype analy sis of myeloid granulocytes might be useful for the diagnosis of MDS patients and AA patients.