多模式镇痛在幻肢痛预防中的临床研究

为探讨多模式镇痛预防截肢后幻肢痛的临床效果。选择50例下肢截肢患者，随机分为2组，试验组（Ⅰ组）和对照组（Ⅱ组），观察患者疼痛评分，患者自控镇痛按压次数，使用其他镇痛药物的情况，记录所有的不良反应及幻肢痛发生率。结果显示，镇痛评分，Ⅱ组高于Ⅰ组（P〈0．01）；PCA按压次数，Ⅱ组多于Ⅰ组（P〈0．01）；不良反应发生率Ⅱ组高于Ⅰ组（P〈0．01）；Ⅱ组幻肢痛发生率明显高于Ⅰ组（P〈0．01）。采取多模式镇痛预防幻肢痛是安全有效的。

Clinical Investigation on Multimodal Analgesia to Prevent Phantom Limb Pain

To evaluate the effects of multimodal analgesia （MMA） to prevent phantom limb pain, 50 lower extremity amputees were randomly divided into two groups, Group Ⅰ （Multimodal Analgesia） and Group Ⅱ （routine postoperative analgesia）. Visual analogue scale （VAS） scores, PCA press times, vital signs and side--effects were assessed. VAS scores, PCA press times were significantly lower in Group Ⅰ than that in group Ⅱ （P〈0.05）, and side--effects were significantly lower in Group Ⅰ than that in group Ⅱ （P〈0.05）. The incidence rate of phantom limb pain were significantly lower in Group Ⅰ than that in group Ⅱ （P〈0.01）. Multimodal analgesia can provide more effective and satisfied analgesia than routine postoperative analgesia to prevent phantom limb pain.