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Stressful Life Events and Distress in Breast Cancer: A 5-Years Follow-Up
Institution:1. Psycho-oncology and ICOnnecta''t digital Health sevices, Institut Català d''Oncologia, Spain;2. Clinical Psychology and Psicobiology Department. University of Barcelona, Spain,;3. Psycho-Oncology and Digital Health, Research in health services in cancer, Institut d''Investigació Biomèdica de Bellvitge (IDIBELL), Hospitalet del Llobregat, Spain;4. Barcelona Biomedical Research Park, Institut Hospital del Mar d''Investigacions Mèdiques (IMIM), Spain;5. Cancer Screening Unit, Institut Català d''Oncologia, L''Hospitalet de Llobregat, Spain;6. Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona. Biomedicine Institute of the University of Barcelona (IBUB), Spain;7. Network Centre for Biomedical Research in Mental Health (CIBER of Mental Health, CIBERSAM), Spain;8. Brain Research Institute, Center for Cognitive Science, University of Bremen, Germany;9. Department of Psychology and Education Sciences, Open University of Catalonia, Barcelona, Spain;10. Department of Psychology, Universitat Abat Oliba CEU, Spain
Abstract:Background/ObjectiveEnvironmental factors such as psychosocial stress have demonstrated to have an impact on the breast cancer (BC) course. This study aims to explore the impact of psychotherapy and stressful life events (SLE) on BC survivors’ illness trajectories.Method68 women with BC underwent Positive Psychotherapy or Cognitive-Behavioral Stress Management and 37 patients were included as a control group. The effects of distress reduction and SLE on their 5-year recurrence were investigated. Additional analyses examined the effect of receiving vs. not receiving psychotherapy and of the type of therapy on survival and disease-free interval, DFI.ResultsA one-point decrease of the Hospital Anxiety and Depression Scale (HADS) after psychotherapy predicted a lower risk of 5-year recurrence, OR = 0.84, p = .037, 95% CI = 0.71-0.99). Also, a one point-increase in the number threatening SLE (OR = 1.92; p = .028, 95% CI = 1.07-3.43) was related to higher 5-year recurrence.ConclusionsThe findings highlight the necessity of studying not only a given situation (i.e., psychotherapy, SLE) but its specific impact on individuals.
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