Severe psychosis and the adrenal androgens |
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Authors: | James S. Howard M.D. |
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Affiliation: | 1. Dept. of Health, P.O. Box 11867, 93775, Fresno, CA
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Abstract: | Past literature suggests a link between certain psychotic states and adrenal androgen production, including Dehydroepiandrosterone (DHEA). A group of severely psychotic androgenized females, refractory to substantial amounts of neuroleptics, has been identified for whom endocrine testing revealed abnormaly high levels of DHEA. A similar group has been identified among the severely psychotic male population. Improvement in psychosis appears to occur as DHEA returns to its normal range using standard low dose Dexamethasone suppression. |
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