| 围肝癌根治切除术期需行经肝动脉化疗栓塞吗 |
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| 引用本文： | 史颖弘.围肝癌根治切除术期需行经肝动脉化疗栓塞吗[J].医学与哲学,2011(6):14-15. |
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| 作者姓名： | 史颖弘 |
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| 作者单位： | 复旦大学附属中山医院肝癌研究所,上海200032 |
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| 摘 要： | 经肝动脉化疗栓塞是原发性肝癌围手术期常见的辅助治疗手段。对于可手术切除的肝癌，化疗栓塞可以缩小肿瘤，提高可切除率；还可能清除潜在的肝内播散灶，减低术后的复发率。但介入治疗本身可以加重肝脏的损伤，并可能诱导肿瘤血管生长因子分泌，肿瘤血管增生等，增加肿瘤播散的机会。临床随机对照研究并没有发现围手术期化疗栓塞能提高肝癌患者的...
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| 关 键 词： | 肝细胞癌 肝切除 经肝动脉化疗栓塞 |
Adjuvant Transarterial Chemoembolization for Resectable Hepatocellular Carcinoma |
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| SHI Ying hong.Adjuvant Transarterial Chemoembolization for Resectable Hepatocellular Carcinoma[J].Medicine & Philosophy:Humanistic & Social Medicine Edition,2011(6):14-15. |
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| Authors: | SHI Ying hong |
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| Institution: | SHI Ying hong.(iver Cancer Institute, Zhongshan Hospital, Fudan Univeristy, Shanghai 200032, China) |
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| Abstract: | Adjuvant transarterial chemoembolization （TACE） is a common therapeutic modality for reseetable hepatocellular carcinoma （HCC）. TACE has been employed to improved resectability by down--staging preoperatively and prevent re currence by controlling the occult intrahepatic tumor postoperatively. However, the effectiveness of TACE has been com- promised by treatment--related liver dysfunction and hypoxia induced tumor angiogenesis. There is no obvious evidence that adjuvant TACE can improve overall survival for resectable HCC in randomized control studies, although it is effica cious procedure for some postoperative patients with high recurrent risks. |
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| Keywords: | hepatocelluar carcinoma liver resection transarterial chemoembolization |
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