| Abstract: | Anticipatory reactions are hypothesized to affect physiological conditions through multiple processing systems. To determine whether anticipatory reactions include the immune system, immune variables from 73 patients treated with immunomodulating chemotherapy for breast or ovarian cancer were studied in a hospital treatment setting and compared with samples obtained in the patients' homes 2 days earlier. The number of white blood cells increased significantly between samples. Increases were also observed in the counts and proportions of granulocytes, while decreases were observed in the counts and proportions of lymphoyctes. No changes were observed in a healthy control group. The nervous system executes regulatory effects on the formation and distribution of leukocytes. Such mechanisms render psychological influences on blood samples possible, including samples that form the basis for decisions related to cancer treatment. The immune changes observed are discussed in relation to mechanisms and adaptive values of anticipation and neurally mediated impacts on the immune system. |
