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Inhibitory attentional control in patients with frontal lobe damage
Authors:Dimitrov Mariana  Nakic Marina  Elpern-Waxman Jordan  Granetz Joy  O'Grady Joy  Phipps Michael  Milne Elizabeth  Logan Gordon D  Hasher Lynn  Grafman Jordan
Affiliation:Cognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bldg. 10, Room 5C205, 10 Center Drive, MSC 1440, Bethesda, MD 20892-1440, USA.
Abstract:The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control-the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.
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