Effect of name agreement on prefrontal activity during overt and covert picture naming |
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Authors: | Email author" target="_blank">Irene?P?KanEmail author Sharonl?L?Thompson-Schill |
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Institution: | Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6241, USA. ikan@psych.upenn.edu |
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Abstract: | In recent neuroimaging studies, various tasks have been used to examine prefrontal cortex involvement in semantic retrieval
and selection. One such task, picture naming, has yielded inconsistent results across studies. One potential explanation for
this inconsistency is that the magnitude of prefrontal activity during picture naming depends on the extent to which a given
picture evokes a single reliable meaning. To test this hypothesis, fMRI activity in the prefrontal cortex was measured while
subjects named pictures with either high or low name agreement. In Experiment 1, subjects named black-andwhite line drawings,
either covertly or overtly. Across both modalities, we found more left inferior frontal gyrus (LIFG) activity when the subjects
named low-agreement pictures than when they named high-agreement pictures. No significant difference in head movement was
detected between the two modalities. In Experiment 2, we replicated the effect of name agreement on LIFG activity during picture
naming, using black-and-white photographs. These results provide further support for the idea that the LIFG mediates selection
among competing alternatives and suggest a means for understanding the naming deficits observed in nonfluent aphasia. |
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