活动性肺结核患者生活废弃物处理现状研究

了解居家治疗的活动性肺结核患者生活废弃物的处理现状及认知态度.本研究采用多阶段随机抽样方法,选取720例居家治疗的活动性肺结核病患者,使用自制调查问卷进行回顾性调查,采用多因素回归对居家治疗活动性肺结核病患者生活废弃物处理的影响因素进行分析.研究发现超过半数患者对生活废弃物处理持积极态度,但仅有19.6％的患者能正确处理生活废弃物.Logistic回归分析发现患者对生活废弃物处理的态度、对督导态度以及是否有专人督导是能否正确处理生活废弃物的影响因素.因此,对患者普及生活废弃物处理的意义及方法,加强对患者督导有助于改善居家治疗活动性肺结核病患者生活废弃处理现状,对于预防结核病传播、实施遏制结核病策略具有重要意义.     

妊娠合并结核临床诊治的决策

妊娠合并结核是一种对母婴健康危害极大的妊娠期疾病。在妊娠期结核病中,多数患者无明显症状,早期症状与妊娠期某些生理反应相似,加之妊娠与结核病的相互影响,x线、CT等重要的影像学检查受限,致使本病易被误诊或误治。某些抗结核药物对母婴的不良影响,使其治疗难以实施,由于结核病本身及治疗后可能对胎儿的影响,在临床上是否终止妊娠往往难以决策。本文就妊娠合并结核诊治过程中的相关问题进行综述,以期为临床诊治决策提供帮助。     

Tuberculosis detection by giant african pouched rats

In recent years, operant discrimination training procedures have been used to teach giant African pouched rats to detect tuberculosis (TB) in human sputum samples. This article summarizes how the rats are trained and used operationally, as well as their performance in studies published to date. Available data suggest that pouched rats, which can evaluate many samples quickly, are sufficiently accurate in detecting TB to merit further investigation as a diagnostic tool.     

耐多药肺结核患者首次就诊过程调查

了解现阶段耐多药肺结核患者的首次就诊过程,分析医患双方对耐多药肺结核患者就诊过程的影响。在全国选取5个项目市,使用自制调查问卷采取面对面方式对样本人群进行访谈式调查。耐多药肺结核患者以文化水平较低、年龄偏大的农民为主。32.6%的患者初次就诊时有全身乏力或消瘦症状,37.6%的患者初次就诊单位为村卫生室或乡镇卫生院,28.4%的患者初次就诊时被误诊,31.6%的患者发生就诊延迟,79.8%的患者在结核病专科医院或防治机构确诊,33.3%的患者确诊延迟。加大对群众结核病相关知识宣传力度,加强结核病防治机构技术力量尤其是实验室诊断技术,加强对参与结核病防治工作医生尤其是村医的专业培训,针对医疗机构转诊建立适当的激励机制。     

结核患者服药依从性的研究现状

结核病控制是全球卫生工作的一个重点,服药依从性则是其中关键的一环。本文对结核患者服药依从性的重要性、影响因素及提高依从性的措施进行综述,认为实施直接督导短程化疗（DOTS）、强化督导、改善患者对服药依从性的认识、简化给药方案、减轻患者经济负担、设置患者提醒物等可提高服药依从性。     

结核病直接督导短程化疗策略的伦理学视角

从伦理学角度探讨了结核病直接监督下短程化疗(DOTS)策略以及DOTS策略实施过程中若干问题。DOTS策略被认为是当今结核病诊治和管理的最有效方法,体现了医学伦理学的公益论;尊重病人的选择及隐私是有效控制结核的重要内容,标准化疗方案和个体化疗方案应视病情而定;医务人员应有良好的综合素质。     

特殊人群结核病的流行病学调查

为了了解某监狱犯人中结核病的患病及结核菌耐药情况,为防治提供依据,采用痰检和结核菌素试验的方式对研究对象进行普查,结核分枝杆菌采用罗氏培养,药敏试验采用比例法。结果显示,PPD试验总阳性率为60．54％。痰检发现24例患者,涂阳患病率为898．54／10万。培养菌株总耐药率为95．83％,其中初治耐药率、复治耐药率和多重耐药率分别为87．5％,100％和73．91％。提示该特殊人群结核病患病率高于一般人群。     

Situating Standards in Practices: Multi Drug-Resistant Tuberculosis Treatment in India

Public health care needs to cope with a basic dilemma between providing standardized care within public programmes across entire and at times resource-constrained countries and adapting this care locally when responding to individual needs. This tension between standardization and local adaptation becomes particularly obvious for the prolonged and complicated treatment of multidrug-resistant tuberculosis (MDR-TB). Situated standardization, as introduced by Zuiderent-Jerak [2007a, 2007b] offers a way out of this dilemma. It helps to focus on how standards need to be situated in practice rather than viewing standardization and local adaptation as mutually exclusive practices. How do actors relate standardization and individual care in their practices of treating MDR-TB? Results from qualitative fieldwork at the first MDR-TB treatment sites of the Indian TB programme show that actors situate standards in a particular way. They assess the role of guidelines in a particular situation and on that basis recognize the core recommendations of guidelines or go beyond the guidelines. This allows actors to negotiate how standards should be situated and reconciles the dilemma between local adaptation and standardization. Having guidelines internalized, as is common for Indian TB control, bears both promises and pitfalls for engaging in standardization processes in a situated manner. The results contribute to science and technology study scholarship on guideline development. They highlight how actors coordinate the situating of standards and how this depends upon cultures of control. This illustrates the potential of qualitative studies on local adaptation for guideline developers by revealing existing practices of relating and negotiating local adaptation and standardization.     

结核病防治中的人文关怀

结核病的防治不仅仅是公共卫生问题,更是一个社会问题。尽管在现阶段结核病防治中已体现了人文关怀的精神,在今后结核病防治中还需要进一步做到重视社会宣传教育,加强家庭督导作用,强化对流动人口中DOTS策略的实施,力争医疗保险参与防治减轻患者经济负担,研制新疫苗等,从而降低我国疫情,促进构建和谐社会。     

从社会医学角度看我国结核病的防治

结核病目前在我国仍是一个重大的公共卫生问题。针对目前我国结核病防治过程中存在的一些问题以及DOTS策略的实施,从社会医学的角度思考认为,结核病的防治不仅仅是公共卫生问题,更是一个社会问题。传统的结核病防治思路有待商榷和完善,DOTS策略的实施应当紧密结合社会各因素,这为今后更好开展结核病防治工作提供了参考。