Composite Deep Belief Network approach for enhanced Antepartum foetal electrocardiogram signal

Antepartum Foetal surveillance is the most vital epoch of investigation during the pregnancy period. This surveillance would provide an opening to plan and manage the Foetus during Intrapartum and Antepartum stages of pregnancy. Moreover, it will help to identify high risk Foetuses during pregnancies which are complicated by maternal health conditions like diabetes mellitus, intrauterine growth restriction, etc. The foetal electrocardiogram (fECG) signal can be detected in the course of pregnancy from the Antepartum stage. Generally, fECG signal analysis is not carried out for Foetal surveillance. Rather, the traditional methodologies like phonocardiogram, etc. are being utilized. The reason is the unavailability of an effective methodology for providing good quality fECG signal. The proposal of a hybrid tactic called Bayesian Deep Belief Network (BDBN) for fECG signal enhancement is presented in this article. The proposed BDBN technique involves Baye’s filtering methodology in amalgamation with Deep Belief Network. The Baye’s filtering was employed to eliminate undesired signal components. Deep learning (DL) technique was utilized with Deep belief network (DBN) to extract high quality fECG signal. The methodology resulted with good quality fECG signal which is indeed valuable for timely Physician analysis.     

A call to restructure the drug development process: Government over-regulation and non-innovative late stage (Phase III) clinical trials are major obstacles to advances in health care

The history of drug/vaccine development has included major advances guided primarily by risk/benefit analyses concerning the innovative agent, not by evidence-based clinical trials (Phase I–IV). Because the approval for new drugs is hindered under the present process, the system requires restructuring. The Phase I/II study period should be more flexible, using the “environment of knowledge” about the new agent, plus risk/benefit assessments. Phase III, as presently constructed, does not add new adverse events data, it provides a narrower profile of drug efficacy than properly done Phase II studies, and placebo-controlled trials continue to raise unresolved ethical and social issues. Phase III studies should be abandoned for most drugs, and substituted with properly powered Phase II doseranging studies plus careful post-marketing surveillance. Phase III should be a penalty for poor drug development, not a regulatory requirement. To accomplish efficient drug development, greater cooperation between pharmaceutical companies and governments in developing clinical trials is needed rather than over-regulation. These changes will synchronize the drug development and regulatory process with the current rapid drug discovery process, reduce drug development time and cost, and improve patient care. The author is Adjunct Professor of Medicine, Weill Medical College of Cornell University, New York, New York, USA.     

I've Got My Eyes on You: Implicit Social‐Pressure Cues and Prosocial Behavior

Explicit social pressure has been shown to be a powerful motivator of prosocial behavior‐like voting in elections. In this study, I report the findings of a randomized field experiment designed to study the impact of more subtle, implicit social‐pressure treatments. The results of the experiment, conducted in the October 2011 municipal elections in Key West, Florida, demonstrate that even subtle, implicit observability cues can effectively mobilize citizens to vote, perhaps as much as explicit surveillance cues. The findings speak more broadly to our understanding of human decision making, and even evolution, and provide fodder for the claim that humans are evolutionarily programmed to respond to certain stimuli. I interpret the evidence to support the notion that evolutionarily charged impulses, like exposure to images that implicitly signal the potential for surveillance and observability, are sufficient to overcome powerful collective action incentives to free ride.     

Holding fat stereotypes is associated with lower body dissatisfaction in normal weight Caucasian women who engage in body surveillance

This study examined the moderating effect of body surveillance on the relationship between fat stereotype endorsement and body dissatisfaction in normal weight women. Participants (N = 225) completed online measures of fat stereotyping, body surveillance, body dissatisfaction, and internalized thin ideals. After accounting for thin ideals, body surveillance moderated the relationship between fat stereotypes and body dissatisfaction. Contrary to hypotheses, higher fat stereotype endorsement predicted lower body dissatisfaction in women with higher body surveillance. Conversely, higher fat stereotype endorsement predicted greater body dissatisfaction in women with lower body surveillance. Thus, endorsing fat stereotypes appears protective against body dissatisfaction in normal weight women who extensively engage in body surveillance. For women who hold fat stereotypes and report high body surveillance, we propose that downward appearance comparison may create a contrast between themselves and the people with overweight whom they denigrate, thus improving body dissatisfaction.     

Examining an elaborated sociocultural model of disordered eating among college women: The roles of social comparison and body surveillance

Social comparison (i.e., body, eating, exercise) and body surveillance were tested as mediators of the thin-ideal internalization-body dissatisfaction relationship in the context of an elaborated sociocultural model of disordered eating. Participants were 219 college women who completed two questionnaire sessions 3 months apart. The cross-sectional elaborated sociocultural model (i.e., including social comparison and body surveillance as mediators of the thin-ideal internalization-body dissatisfaction relation) provided a good fit to the data, and the total indirect effect from thin-ideal internalization to body dissatisfaction through the mediators was significant. Social comparison emerged as a significant specific mediator while body surveillance did not. The mediation model did not hold prospectively; however, social comparison accounted for unique variance in body dissatisfaction and disordered eating 3 months later. Results suggest that thin-ideal internalization may not be “automatically” associated with body dissatisfaction and that it may be especially important to target comparison in prevention and intervention efforts.     

Eating pathology in female gymnasts: Potential risk and protective factors

Although participation in sports that emphasize aestheticism, such as women's gymnastics, are associated with higher rates of eating pathology, little is known about the risk and protective factors involved in this process. We established and tested a model proposing that body surveillance and body shame are processes by which pubertal development and training may uniquely contribute to pathological eating by sampling 100 competitive female gymnasts via questionnaires. We further tested whether self-esteem moderated several model relationships. Results demonstrated that pubertal development was associated with higher levels of body surveillance, body shame and disordered eating; whereas greater time spent training was associated with lower levels of body shame and disordered eating. Finally higher self-esteem was associated with lower levels of disordered eating, less body surveillance, and less body shame. Potential risk and protective factors for the development of eating pathology in female gymnasts are discussed.     

A New Methodology for Reporting the Status of Community Health Improvement in the United States

Objective To assure that Healthy Communities are achieved, a tracking methodology is proposed using four health improvement categories. Methods Counties are classified as having met or not met nine HP2010 mortality targets and as improving or not improving, creating four categories of community health improvement – static, progressing, exemplary, and maintaining. Results Exemplary counties make up 1.7%32.7% of counties, counties have both improved and met the HP2010 target during the period. Across all indicators, a large proportion remains of counties that have neither met the HP2010 target nor improved (33.572.8%). Conclusions Understanding why, how, and in what ways communities move from static to maintaining categories is necessary to guiding every local public health system to community health improvement.     

Managing Old Age: The Disciplinary Web of Power, Surveillance and Normalization

Health and welfare have emerged as key vehicles used to legitimize and position the identities that older people adopt in contemporary western societies. Both health and welfare contain specific yet continually changing technologies that function to mediate relations between older people and the state. Medico-technical and care management discourses have been presented as adding choice and reducing limitations associated with adult aging. However, they also represent an increase in professional control that can be exerted on lifestyles in older age and thus, the wider social meanings associated with that part of the lifecourse. This article presents a theoretical analysis based on a critical reading of the work of Michel Foucault; identifies the interrelationship between managers and older people in terms of power, surveillance and normalization; and highlights how and why older people remain the subjects of legitimizing professional gazes.     

The Politics of Biometric Standards: The Case of Israel Biometric Project

In 2017, after years of public debate, Israel ratified a national biometric project consisting of two initiatives: issuing of biometric ID cards and passports to all Israeli citizens and establishment of a centralized database for storing their bodily information. Design and implementation of a preceding four-year pilot study were accompanied by extensive standardization. Discourse and standard analyses of 33 official state documents – from legal records to performance reports – published by Israeli authorities during the pilot study, unravel the politics of biometric standards employed as part of this project. Biometric standards were used to establish hierarchies between individuals and groups by defining particular bodies as ‘biometrically ineligible.’ These individuals are mostly members of underprivileged and marginalized social groups. Biometric standards were also constructed discursively as scientific and objective to legitimize such discriminatory treatment. Israeli authorities used standards strategically, both as infrastructural elements and as a discursive means. As infrastructural elements, biometric standards were employed, inter alia, to achieve predetermined results and confirm the project’s success. As a discursive means, Israeli authorities actively adopted a ‘discourse of standardization’ to construct an objective and fair image to the project. Standardization of people – namely, quantification of lives, bodies and experiences – is inherently discriminatory because it necessarily results in the creation of categories and hierarchies between biometrically in/eligible bodies.     

Self‐supervision,surveillance and transgression

Transgression is not only an inevitable part of systemic supervision but is also necessary if we are to work towards innovative and inclusive supervisory and therapeutic practice. Defying culturally generated ‘rules’ of systemic practice can allow for more relevant and productive ways of talking. Systemic practitioners are increasingly finding themselves trying to practice systemic therapy in employing authorities and training courses which are dominated by inflexible professional narratives and manualised procedures. Our profession is committed to ethical inner and outer dialogue, to self‐ and relational reflexivity as distinct from the rule‐bound surveillance culture in which we live and work. Systemic supervisors and therapists may find themselves at odds with monological institutional discourse and attempts from within our own profession to manualise practice. I introduce examples from supervisory conversations to illustrate how supervisors can develop more culturally sensitive practices through supporting practitioners to hear and have heard their own marginalised and oppressed voices and those of their clients.