1例特重度烧伤创面自然愈合的启示

火药爆炸致1例男性青年烧伤面积40％TBSA,深Ⅱ度10％、Ⅲ度30％,伴有左小腿大隐静脉坏死、胫腓骨暴露。伤后32天采用煨脓生肌疗法治疗,15个月40面自然愈合,照片记录治疗过程中创面环境的动态变化和愈后皮肤质量,再现组织的再生潜能和机制,彰显煨脓生肌疗法治疗烧伤独特的理念、疗效和人文精神。     

关于牙齿再生研究的述评

牙齿再生医学是目前口腔医学中面临的最为重要的科学问题,成为口腔医学研究领域的热点。无论从牙发育生物学到牙生物信息学到牙组织工程技术,由此而得到了很大程度的发展。但是,这个领域目前面临许多问题。就有关研究的现状、困惑、面临的问题进行探讨,对于牙再生医学研究的模式,从方法论的角度提出探讨。引发相关研究领域研究人员思考,以早日实现牙齿组织再生,满足人们需要。     

Can regenerated inner‐city areas remain sites of public‐place sociability? Psycho‐social processes predicting public sociability in a changing neighbourhood

The processes of urban regeneration of long‐disinvested inner‐city neighbourhoods today happening in many European cities sometimes dramatically transform residents' traditional uses of their public places. Focusing on a neighbourhood renowned for its traditional public place sociability – Mouraria, in Lisbon – this study explored the psychosocial processes that may shape the maintenance of that sociability in the face of increasing social diversification and small‐scale gentrification brought about by a mixed/bottom‐up regeneration plan. A questionnaire survey (n = 201) with two types of residents (“traditional residents” and “new gentrifiers”) indicated that: (a) both types report using Mouraria's public places for socializing, although traditional residents do so to a greater degree; (b) perceived cultural continuity of the neighbourhood is positively related to public place sociability for both groups; and (c) this relationship is mediated by both place identification and place knowledge; but (d) it is not moderated by type of resident. By implication, we argue that regenerated inner‐city neighbourhoods may remain as places of lively public sociability and companionship if residents are able to forge and/or retain a sense of identification with, and intimate knowledge of, the neighbourhood, and view it as maintaining continuity with the past.     

Long-term rod dark adaptation in man. Threshold measurements, rhodopsin regeneration and allosteric sensitivity regulation. An evaluation

Recent evidence strongly suggests that the relationship between threshold elevation ( T ) and fraction of bleached rhodopsin ( B ), obtained during a major, middle period of long-term rod dark adaptation in man, is well described by a power function, i. e., T = k · Bⁿ , where k is a multiplicative constant and n is the exponent. Due primarily to the low reliability of measurements of rhodopsin regeneration, however, the exponent n of the power function cannot, at present, be given an exact value. Available information indicates that the value of the exponent ranges between 2.4 and 4. Implications of this uncertainty are discussed within the framework of the allosteric, tetrameric model of rod dark adaptation. It is concluded that this model in its simplest form may only offer a first approximation of the real system implicated in the process.     

Can affective atmospheres justify megaprojects? A case study of the ‘Asia New Bay Area’ in Kaohsiung,Taiwan

This article examines how affective atmospheres are constituted and used to sustain regeneration megaprojects. I argue that certain affective atmospheres engendered in particular urban contexts are essential to facilitating transformation in contemporary urban areas. Through the convergence of affective encounters, spatial imaginations and common goals in performative ways, affective atmospheres are forged and circulated to legitimise political decisions and urban policies. Moving beyond the conventional approach to examining waterfront regeneration, this paper attempts to capture the inherent relationship between affective dynamics and spatial practices that characterises megaprojects and dominates public opinion.The key claim of this article is that regeneration projects are emotionally mediated and sustained on the foundations of affective atmospheres in which myriad affects underlying everyday life are assembled to enhance municipal power and direct pubic concerns. The presented case study shows that the Asia New Bay Area (ANBA) project activated an affective atmosphere in a context-specific way, in which affective sensations situated in place experiences are assembled to challenge the physical and political landscape. It demonstrates that unfolding the city's affective, emotional and atmospheric resonances is critical to grasping how the megaproject can be justified and, furthermore, the orientation and rationale of spatial practices. Finally it outlines pragmatic suggestions for policy reform that address regeneration megaprojects in socially meaningful ways.     

胰岛细胞再生研究的临床应用前景

胰岛细胞再生是治愈1型糖尿病和胰岛β细胞功能丧失的2型糖尿病的根本途径。体外再生和体内再生两种策略都是通过将干细胞或其他类型体细胞分化或转化为胰岛细胞后发挥胰岛素分泌功能,从而治疗糖尿病。基础研究显示,两者存在着各自的优势和面临的问题。胰岛细胞再生治疗的临床应用前景尚需要进一步加以考证。     

生物工程领域的崭新前沿--组织工程

组织工程是在组织水平上操作的生物工程,主要致力于组织和器官的形成和再生,它是对外科领域中组织、器官缺损和功能障碍传统治疗方法和模式的一次革命。同时组织工程是一门多学科交叉的边缘学科,将是２１世纪具有巨大潜力的高技术产业,必将产生巨大的社会和经济效益。     

胰岛再生治疗的前景

胰岛β细胞数量减少和功能障碍是糖尿病的根本原因,现有的治疗手段主要以维持正常血糖水平为主要目的,尚无有效恢复受损胰岛功能的治愈性治疗手段。胰岛再生治疗将是一种可以恢复受损胰岛功能、改变糖尿病自然病程的崭新治疗手段。目前现有的噻唑烷二酮、肠促胰岛素及类似物、二肽基肽酶-4抑制剂等治疗,虽然不是一类新的胰岛再生药物,但其具有一定的促进胰岛再生、改善胰岛功能的作用。体外诱导β细胞再生也将为胰岛移植提供新的来源,为治愈糖尿病带来曙光。