Displacement trauma: complex states of personal,collective and intergenerational fragmentation and their intergenerational transmission

Originally presented at the Journal’s one day conference entitled ‘Displacement: Contemporary Traumatic Experience’ held in London in November 2019, this paper expands on the author’s theory of the implicit psychological organizing gestalt, an associated pattern of psychic functions which operate in an integrated way to simultaneously structure and organize our experience of self-cohesion and self-continuity. The gestalt, which implicitly links the formation of psychic skin, body image, cultural skin and both personal and cultural identity with place, functions as an emergent non-conscious permanent presence or background ‘constant’. It develops over time and emerges out of embodied emotional experiencing with the total environment – both human and non-human. The author argues that it is the rupture of this gestalt and the disorganizing consequences of its loss which underlies the experience of displacement trauma. If disruptions in the formation of the gestalt and/or its later rupture remain unrecognized and unrepresented then the absence creates a void which can be intergenerationally transmitted. Case material is presented which describes this and which highlights the ways in which the gestalt can contribute to our understanding of collective displacement anxiety, cultural trauma and cultural complexes.     

The gap between law and ethics in human embryonic stem cell research: Overcoming the effect of U.S. Federal policy on research advances and public benefit

Key ethical issues arise in association with the conduct of stem cell research by research institutions in the United States. These ethical issues, summarized in detail, receive no adequate translation into federal laws or regulations, also described in this article. U.S. Federal policy takes a passive approach to these ethical issues, translating them simply into limitations on taxpayer funding, and foregoes scientific and ethical leadership while protecting intellectual property interests through a laissez faire approach to stem cell patents and licenses. Those patents and licenses, far from being scientifically and ethically neutral in effect, virtually prohibit commercially sponsored research that could otherwise be a realistic alternative to the federal funding gap. The lack of federal funding and related data-sharing principles, combined with the effect of U.S. patent policy, the lack of key agency guidance, and the proliferation of divergent state laws arising from the lack of Federal leadership, significantly impede ethical stem cell research in the United States, without coherently supporting any consensus ethical vision. Research institutions must themselves implement steps, described in the article, to integrate addressing ethical review with the many legal compliance issues U.S. federal and state laws create. The opinions expressed in this article are the author’s own, and are not necessarily the opinions of others, including Children’s Hospital Boston. Portions of earlier versions of this article were previously published by the American Bar Association and the New York State Bar Association.     

Deficit in selective and divided attention associated with cholinergic basal forebrain immunotoxic lesion produced by 192-saporin; motoric/sensory deficit associated with Purkinje cell immunotoxic lesion produced by OX7-saporin

The immunotoxin 192-saporin, infused intracerebroventricularly into rats, destroys cholinergic neurons in the basal forebrain nuclei. Doses required for complete cholinergic loss also kill some Purkinje cells. The immunotoxin OX7-saporin, when infused intraventricularly into rats, destroys Purkinje cells in a pattern similar to that produced by 192-saporin, without affecting cholinergic neurons. Thus, we used OX7-saporin to distinguish behavioral effects of 192-saporin due to cerebellar damage versus those due to cholinergic cell loss. Three doses of 192-saporin (1.6, 2.6, and 3.3 micrograms/rat) were chosen along with a dose of OX7-saporin (2.0 micrograms/rat) that produced Purkinje loss equivalent to the two highest doses of 192-saporin. Groups of Fischer-344 rats were trained in the multiple choice reaction time task and retested with more complex tasks after lesioning. They were also tested in the water maze, passive avoidance, acoustic startle, and open field. The OX7-saporin group exhibited changes in many tests suggesting hypermotility and sensory deficits. The 192-saporin groups differed from the OX7-saporin group when they displayed deficits in multiple choice reaction time tasks in which novel challenges were introduced, including sessions with a noise distractor, shortened and lengthened intertrial intervals, and use of nine instead of five sources of light stimulus. The 192-saporin groups showed no impairment in the other tasks. The cholinergic basal forebrain lesion may mask some of the effects of cerebellar damage up to a threshold after which effects of Purkinje cell loss predominate when 192-saporin is administered intraventricularly.     

Servicescapes: The role that place plays in stay‐at‐home mothers’ lives

Over the past decade, increasing attention has been paid to gender‐related consumption behaviour. However, a relative gap in our knowledge still exists when it comes to understanding the changes that occur as a result of motherhood and how this may influence their interactions in the retail environment. The purpose of this article is to explore stay‐at‐home mothers’ experiences in the servicescape to gain a better understanding of how they associate with servicescapes during this transitional period, how they use retail space to suit their needs, and how they use retail space to negotiate their role as a stay‐at‐home mother. Five stay‐at‐home mothers with children younger than 5 years were provided with disposable cameras and asked to photograph servicescapes that they visited regularly. Over a 1‐year period, they were interviewed several times, and photo‐elicitation techniques were used throughout the interviewing process. The results of this study suggest that when consumers undergo role or identity changes, certain places can be used to smooth this process. Not only can the retail environment be used as a coping mechanism for stay‐at‐home mothers, it can also be viewed as a “second place” as opposed to a “third place”, thus enabling isolated consumers to feel connected with the outside world. Last, this study highlights the temporal dimensions of place. Throughout one's lifetime, one will form attachments to and patronise different places, which will evolve and change as individuals, accordingly, take on different roles and identities. Copyright © 2012 John Wiley & Sons, Ltd.     

微流控分析芯片在循环肿瘤细胞检测中的运用

随着人们对于肿瘤性疾病的发生、发展、转移机制的进一步探索,循环肿瘤细胞（CTCs）逐渐进入人们视野,其应用价值日益体现,可用于肿瘤性疾病的早期诊断及治疗效果的监测,尤其是对于早期肿瘤的诊断具有独特优势。其富集技术及检测方法也在发生着日新月异的变化。近年来,微流控分析芯片技术运用于 CTCs 的富集及检测,具有高丰度、高富集度、高活性及不需要对样本进行预处理等优点使得人们聚焦于此技术,本文对微流控分析芯片在 CTCs 检测中的运用做简要综述。     

TACE联合RFA序贯DC-CIK治疗小肝癌的研究进展

射频消融术（RFA ）、肝动脉化疗栓塞术（TACE）及 DC-CIK 治疗等非手术方法已成为治疗小肝癌的重要手段。RFA 及 TACE 直接杀伤肿瘤细胞,DC-CIK 治疗明显改善机体免疫功能。 TACE 联合 RFA 术后序贯 DC-CIK 治疗可取长补短,提高治疗的有效性、安全性及患者的远期疗效。本文主要对 DC-CIK 治疗、TACE 、RFA 治疗现状及联合治疗前景做一综述。     

Demonstration and interpretation of ‘scutoid’ cells formed in a quasi-2D soap froth

ABSTRACT

Recently a novel type of epithelial cell has been discovered and dubbed the ‘scutoid’. It is induced by curvature of the bounding surfaces. We show by simulations and experiments that such cells are to be found in a dry foam subjected to this boundary condition.     

Physical,Psychological and Social Adaptation of African American Nuns to Their Religious Communities as They Age: Implications for Aging in Place

ABSTRACT

This study examined the association between health status, stress, depression, satisfaction with the relationship with the religious community, alienation from significant persons, racial/cultural identity and “aging in place,” as measured by length of time in the same religious community, for a purposive sample of 72 African American nuns. Aging in place was significantly associated with perceptions of better health status, less stress and depression and greater satisfaction with relationships with the religious community. However, the study also found that the longer the nuns lived in their respective communities, the less racially/culturally identified they became. These findings underscore the need for finding ways to keep nuns in their religious communities as they age and to provide avenues of racial/cultural expression for African American nuns.     

相互作用的认知子系统理论述评

该介绍和分析了“相互作用的认知子系统”理论的基本观点,即信息的意义分为具体的、低层次的意义和一般的、高层次的意义;编码形式的转换遵循着特定的规则;不同信息的存储具有各自独立的记忆存储系统：高层次的意义对情绪产生具有直接作用。同时阐述了该理论对抑郁性情绪障碍的研究,并指出了该研究对治疗情绪障碍的意义及存在的问题。