Parallel distributed processing and neuropsychology: A neural network model of Wisconsin card sorting and verbal fluency

Neural networks can be used as a tool in the explanation of neuropsychological data. Using the Hebbian Learning Rule and other such principles as competition and modifiable interlevel feedback, researchers have successfully modeled a widely used neuropsychological test, the Wisconsin Card Sorting Test. One of these models is reviewed here and extended to a qualitative analysis of how verbal fluency might be modeled, which demonstrates the importance of accounting for the attentional components of both tests. Difficulties remain in programming sequential cognitive processes within a parallel distributed processing (PDP) framework and integrating exceedingly complex neuropsychological tests such as Proverbs. PDP neural network methodology offers neuropsychologists co-validation procedures within narrowly defined areas of reliability and validity.     

Connectionist models of conditioning: A tutorial

Models containing networks of neuron-like units have become increasingly prominent in the study of both cognitive psychology and artificial intelligence. This article describes the basic features of connectionist models and provides an illustrative application to compound-stimulus effects in respondent conditioning. Connectionist models designed specifically for operant conditioning are not yet widely available, but some current learning algorithms for machine learning indicate that such models are feasible. Conversely, designers for machine learning appear to have recognized the value of behavioral principles in producing adaptive behavior in their creations.     

内侧前额皮层-伏隔核环路在决策冲动中的作用：基于动物模型的研究

注意缺陷多动障碍(attentiondeficit/hyperactivitydisorder,ADHD)行为控制不足与决策冲动密切相关,后者受内侧前额皮层(medial prefrontal cortex, mPFC)与伏隔核(nucleus accumbens, NAc)调节。为调查ADHD决策冲动与m PFC-NAc间功能耦合的关系,研究采用ADHD模型SHR (spontaneously hypertensive rat, SHR)大鼠,结合延迟折扣任务和在体电生理,研究发现,与对照Wistar (WIS)大鼠相比, SHR大鼠对延迟大奖赏的选择百分比降低; WIS大鼠m PFC-NAc的Theta频段相干值表现为延迟选择时显著大于立即选择时、首次选择时大于连续选择时、转换试次时大于连续试次时,而SHR大鼠在上述条件均低于WIS大鼠。回归分析发现m PFC-NAc的相干差值与延迟大奖赏选择率显著正相关。结果表明m PFC-NAc间功能联系减弱是ADHD决策冲动缺陷的重要环路基础,该缺陷与其深度信息加工以及策略转换能力受损有关,扩展了ADHD决策冲动的认知和神经机制的认识。     

人类颜色视觉的计算理论

该文有机地结合了计算视觉理论和生态学视觉理论,指出颜色信息处理的根本任务是检测环境中的光不变量。在此基础上,作者提出了颜色视觉的计算理论以及计算理论本身的生物学标准。初级视觉计算是典型的不适定问题,动物的视觉系统则利用视环境中存在的条件将该不适定问题转化为定解问题。本文引入颜色视觉计算的免要条件,客观性约束,以及颜色认知的神经表象,证明了上述约束下颜色算法的存在性。本文给出了构造颜色知觉的基本假设。同时,该文还讨论了与上述问题密切相关的几个基本问题:神经表象的完备性,主观色觉的客观性,明度知觉和颜色知觉的统一,人类主观色觉的实现方式。     

Can we learn from the clinically significant face processing deficits,prosopagnosia and capgras delusion?

This review describes two clinically significant face processing deficits, prosopagnosia and Capgras delusion, and provides new knowledge about the face recognition process by a convergence of empirical findings. These empirical findings are structured around two questions that are viewed from the perspectives of the two deficits. First is the question of hemispheric specificity, which inquires into the degree of each hemisphere's contribution to the face recognition process. Second is the question of dual neural pathways, which addresses the possibility that the face recognition process proceeds along two parallel pathways in the brain. Findings from the hemispheric specificity studies reinforce the current view that right hemisphere involvement is necessary for face recognition while left hemisphere involvement is minimal. Findings from the dual neural pathways studies reinforce the plausible but yet unproven hypothesis that two neural pathways pass information from the visual association cortex in the occipital lobe toward the temporal lobes and limbic system when faces are seen and recognized. These findings, which also indicate that each of the dual neural pathways carries different, nonredundant information, could be instrumental in showing that the pathways play different roles in the manifestations of the clinically significant face processing deficits, prosopagnosia and Capgras delusion.     

Folic acid and the prevention of neural tube defects: A position paper of the national society of genetic counselors

Considerable scientific evidence demonstrates the reduction in risk for neural tube defects (NTDs) associated with maternal preconceptional folic acid supplementation. The National Society of Genetic Counselors (NSGC) endorses the U.S. Public Health Service recommendations for folic acid supplementation at the 0.4 mg level for women in the general population and at the 4.0 mg level for women at high or increased risk for NTD pregnancies for at least 4 weeks prior to active pursuit of conception. We encourage targeted educational efforts and surveillance to assess results of this dietary supplementation. The NSGC further urges the Food and Drug Administration to fortify staple foodstuffs with folic acid for a population-based approach to minimize the number of NTD births.     

A case study of conflicting interests: Flemish engineers involved in environmental impact assessment

This article reports of the activities of the working group, Ethics & Engineers, of the Royal Flemish Society of Engineers. More particularly, the ethical problems that engineers face in the preparation of an environmental report are illuminated. Irrespective to which party the engineer belongs, he or she is confronted with the difficult weighting of his or her personal interest, the interests of private companies and last but not least the common good. It is argued that the implementation of a code of ethics and the introduction of courses on engineering ethics into the education of engineers would strengthen the engineer in the fulfilment of his vocation. Dirk Holemans is a bio-engineer preparing a doctoral thesis on the social responsibility of engineers, Herman Lodewyckx teaches ethics and has research interests in professional and applied ethics.