Brain perfusion and neuropsychological test scores: A correlation study in aphasics

In 26 patients suffering from the pure types of aphasias (11 total, 6 motoric, 5 sensory, and 5 amnesic), hemispheric and regional cerebral blood flow were measured and the flow values were correlated with psychological test scores including Wechsler Adult Intelligence Scale (WAIS), Token Test, Benton Test, and word fluency tests. With respect to the flow values, an overall difference between the groups of aphasics was proved by analysis of variance [regional cerebral blood flow (rCBF): F(3,22) = 13.77, p < .001]. The location of mainly impaired brain perfusion was not always confined to the centers within the speech area expected in view of the clinical disturbance, but most patients had neurologic deficits in addition to their aphasia. High correlations were found between the rCBF values within ischemic foci and WAIS subtests, as well as Token Test and word fluency tests. The correlation coefficients calculated between hemispheric flow and the psychological data indicated, in many instances, the same dependency, but did not attain the high statistical significance obtained with the regional values. The results show dependencies of several aspects of mental function upon cerebral perfusion and provide information for possible mechanisms responsible for the disturbance of nonverbal intelligence in aphasics.     

The neural pathways mediating quiet-biting attack behavior from the hypothalamus in the cat: A functional autoradiographic study

Electrical stimulation of the region of the lateral hypothalamus produced a consistent form of quiet-biting attack behavior in cats. In one series of experiments, cats, implanted with electrodes from which attack had been elicited, were anesthetized and then were injected with a bolus of ¹⁴C-2-deoxyglucose at the same time as electrical stimulation was delivered through the attack electrodes. Brains prepared for X-ray autoradiography revealed that lateral hypothalamic stimulation activated the classical medial forebrain bundle pathway supplying the septal region, diagonal band, lateral preoptic area, and ventral tegmental region. Stimulation of quiet-attack sites in perifornical hypothalamus resulted in the activation of a much more extensive projection system which included the central and lateral tegmental fields of the midbrain and pons, and central gray region, as well as the structures described above. In a second series of experiments, ³H-leucine was placed into the region of the electrode tip from which attack was elicited in order to identify more precisely the pathways arising from that site. In general, tritiated amino acid radioautography replicated the ¹⁴C-2-deoxyglucose findings. In addition, the amino acid radioautographic data revealed the presence of extensive projections from perifornical hypothalamus to such pontine structures as the nucleus locus coeruleus, motor nucleus of NV , and the lateral pontine tegmental field. The functional connections between the lateral hypothalamic “attack region” and lateral preoptic zone were also confirmed by electrophysiological methods.     

On matters of mind and body: regarding Descartes

In this paper the author considers Descartes’ place in current thinking about the mind‐body dilemma. The premise here is that in the history of ideas, the questions posed can be as significant as the answers acquired. Descartes’ paramount question was ‘How do we determine certainty?’ and his pursuit of an answer led to cogito ergo sum. His discovery simultaneously raised the question whether mind is separate from or unified with the body. Some who currently hold that brain and subjectivity are unified contend that the philosopher ‘split’ mind from body and refer to ‘Descartes’ error’. This paper puts forward that Descartes’ detractors fail to recognise Descartes’ contribution to Western thought, which was to introduce the Enlightenment and to give a place to human subjectivity. Added to this, evidence from Descartes’ correspondence with Princess Elisabeth of Bohemia supports the conclusion that Descartes did in fact believe in the unity of mind and body although he could not reconcile this rationally with the certainty from personal experience that they were separate substances. In this Descartes was engaged in just the same dilemma as that of current thinkers and researchers, a conflict which still is yet to be resolved.     

ŚŪNYATĀ AND KOKORO: SCIENCE–RELIGION DIALOGUE IN THE JAPANESE CONTEXT

When we read books or essays about the dialogue between “religion and science,” or when we attend conferences on the theme of “religion and science,” we cannot avoid the impression that they actually are dealing, almost without exception, not with a dialogue between “religion and science,” but with a dialogue between “Christianity and science.” This could easily be affirmed by looking at the major publications in this field. But how can the science–religion dialogue take place in a world where conventional Christian concepts of God, religion, and science are foreign and unfamiliar? Is the critique that the scientist plays God still valid when there is no “God” at all? This article tries to answer the questions mentioned above, and seeks to sketch out some aspects of the science–religion dialogue in Japan which I believe could contribute a new paradigm for understanding and describing ultimate reality.     

An appreciative response to Niels Henrik Gregersen's JKR research conference lecture

Abstract

Using human embryos in research remains a controversial issue, especially in Christian bioethics. Although the official Catholic stance rejects human embryonic stem cell research, Christian thinkers T. Peters, K. Lebacqz and G. Bennett support it. They endorse the 14-day Rule and argue that ex vivo embryos lack moral worth. I examine and challenge the 14-day Rule and location argument (in vivo/ex vivo). I develop a theory of holistic anthropology and intrinsic moral value for human embryos. I conclude that intrinsic moral value is not equal to full moral value, and therefore use of embryos in biomedical research is morally permissible.     

Lutherans in Need of Self‐Discipline: Japanese Shugyō and the Art of Sanctification

Abstract : Lutherans have a reputation for not attending well to the life of sanctification. Whether or not this is deserved, it is clear that all believers should make greater efforts to live in conformity with the will of God. Distinctly lacking in the Lutheran heritage, however, are disciplines of self‐cultivation. Such methods could play a larger role in the spiritual lives of believers, not for the sake of one's own salvation, but for the benefit of others. With that in mind, this article considers the practice of shugyō in Japanese Buddhism. This concept of self‐cultivation can form a model for how we in the West might seek to attend to our own maturing in the Christian life, attending to a greater stewardship of our bodies and minds.     

脂多糖受体mCD14定量研究的方法探讨

本文通过横断面研究,时100例正常人群（一次性）采集外周全血2ml,选用流式细胞技术测定单核细胞群、mCD14平均荧光强度值,行盲法测定。观察正常人群外周血mCD14的表达水平,探讨正常人群mCD14定量研究的方法。结果显示单核细胞与淋巴细胞的比值比单个读取mCD14的平均荧光强度值更具可重复性,集中趋势较好,有利于临床应用和比较研究。此方法可作为流式细胞仪定量检测数据校正的方法参考。     

The effect of anxiety,reinforcement, and intelligence on the learning of a difficult task

The effects of anxiety, reinforcement, and intelligence were studied on the learning of a difficult task (paired associates with 1% association values) in 252 subjects studying in class IX in Chandigarh schools (mean age, 14.7 years). A 2 × 3 × 3 factorial design was used with two anxiety groups (high and low), three reinforcement conditions (praise, reproof, and praise + reproof), and three levels of intelligence (high, middle, and low). In general, the results were in line with the Sarasonian theoretical framework that anxiety shows its debilitating effects under certain conditions, but not all. At upper levels of intelligence, neither anxiety nor reinforcement was found significant. At lower levels of intelligence, anxiety was found to interfere with learning under all the reinforcement conditions. It was found further that the most affected group was the middle intelligencehigh anxiety group. This group performed better under praise than under praise + reproof and reproof alone.