Regional cerebral blood flow response to recognition memory versus semantic classification tasks

Two randomly assigned groups, N = 7 each, of neurologically normal patients were composed. One group, RM, had regional cerebral blood flow measurements during a recognition memory probe test; the other group, SC, had rCBF measurements during a semantic classification task, using the same stimulus and response features as the RM task. Thus, the groups differed only in the cognitive instruction they were executing. The RM group showed a significantly lower change from resting baseline to activation, in mean left hemisphere initial slope index, than did the SC group. The RM group, but not the SC group, showed a significant inverse correlation between occipital flow and accuracy of memory performance as indicated by d′. Correlations between age and hemispheric initial slope index, and between homologous left and right hemisphere sites, were also described. The results are considered to support an anatomical basis for the distinction between episodic and semantic memory and to suggest that occipital flow may diminish with accurate memory performance because of an upstream demand of blood in the medial temporal lobes.     

Regional cerebral blood flow response in a patient with remitted global amnesia

A case of remitted global amnesia, believed to have residual left medial temporal lobe damage, is tested by the same recognition memory paradigm used by Wood, Taylor, et al. in the previous paper. On two different testing occasions, once using an intentional and once an incidental memory procedure, the patient's right occipital flows were inversely correlated with memory accuracy and the values were very close to the regression line for 10 normals relating occipital flow to memory accuracy. The left occipital flows did not fit the regression line, however. The results were interpreted as consistent with the notion that occipital flow is inversely related to medial temporal lobe activation. Another surprising feature of this case is the unexpected persistence of amnesia for a period from about 5 to 10 years before her episode to about 2 weeks after the episode, with recovery of memory functioning for the period since that time.     

Regional cerebral blood flow response during rest and memory activation in a patient with global amnesia

A college professor with a classical amnesic syndrome is described. He has a WAIS IQ of 130, but dramatic memory loss for episodes ranging from a few seconds ago all the way back to portions of his childhood. The amnesia was of sudden onset, 2 years prior to the current memory tests and regional cerebral blood flow measurements. The etiology is believed, though not conclusively proven, to be medial thalamic infarction. rCBF measurements were taken on six separate occasions, four resting baseline, one memory activation, using the previous procedure of Wood, Taylor, et al., and one carbon dioxide activation. The resting baseline showed extremely low flows throughout the cortex, with some hyperfrontal response on the first baseline. With CO₂ activation, however, there was brisk, uniform reactivity, with all sites showing increased flow. This suggested that there were no prominent areas of impaired vasomotor control or probable ischemic damage in the cortical surface. During memory activation, there was also a generalized increase in flow, especially in the frontal areas. This was in sharp contrast to the pattern for normals, described by Wood, Taylor, et al., which shows a slight overall decrease in flow from baseline to memory activation. The results are interpreted in light of Talland's proposal that the amnesic syndrome reflects an arousal failure, with premature closure and shutdown of memory processing, especially at retrieval. Here the arousal failure is interpreted as an inadequate restriction or focusing of cortical activation, with resulting pathologically diffuse flow increases.     

FREEDOM AND THE SOURCE OF VALUE: KORSGAARD AND WOOD ON KANT'S FORMULA OF HUMANITY

Abstract: This essay examines two interpretations of Kant's argument for the formula of humanity. Christine M. Korsgaard defends a constructivist reading of Kant's argument, maintaining that humans must view themselves as having absolute value because their power for rational choice confers value on their ends. Allen Wood, however, defends a realist interpretation of Kant's argument, maintaining that humans actually are absolutely valuable and that their choices do not confer value but rather reflect their understanding of how the objects of their choices fulfill their needs and wants and contribute to their flourishing. Though Korsgaard's reading is more consistent with Kant's prioritizing of the right over the good, this essay raises a metaethical question regarding her constructivist position, namely, “What is meant by her claim that rational choice ‘confers’ value on objects?” In developing this question, it presents a realist account of goodness that is taken from Peter Geach's “Good and Evil.”     

Durkheim,Sellars, and the Origins of Collective Intentionality

Wilfrid Sellars read and annotated Celestine Bouglé’s Evolution of Values, translated by his mother with an introduction by his father (1926). The book expounded Émile Durkheim's account of morality and elaborated his account of origins of value in collective social life. Sellars replaced elements of this account in constructing his own conception of the relationship between the normative and community, but preserved a central one: the idea that conflicting collective and individual intentions could be found in the same person. These notoriously opaque arguments, which seek to save an element of rationalism from social explanation while granting the claims of behavioural science, are illuminated by comparing them to their original Durkheimian form.     

Christ and the Homosexual: An Early Manifesto for an Affirming Christian Ministry to Homosexuals

In his book Christ and the Homosexual (1960), Rev. Robert Wood presented American Christians with a view of homosexuality that was revolutionary: in short, he argued that homosexuals held a rightful place in church and society and that they should abandon neither Christianity nor the church. More specifically, the author called for the advancement of civil rights for homosexuals; the construction of pro-homosexual theologies; the education, ordination, and career placement of “out” homosexuals; and marriage equality for same-sex couples. This article situates these topics within Wood’s lifelong (and ongoing) ministry of promoting the full acceptance of homosexuals in American society and in The United Church of Christ, his own denomination. The following sources from the Robert Wood Archive at The Congregational Library in Boston, MA, USA, have been used in this article: the author’s notes and early drafts of Christ and the Homosexual; his voluminous correspondence from the 1940s through the 1990s; and an unpublished biography of Wood. In addition, this article’s author draws upon an oral history interview conducted with Robert Wood in July 2012.     

Patterns of regional cerebral blood flow during attempted reading aloud by stutterers both on and off haloperidol medication: Evidence for inadequate left frontal activation during stuttering

Two stutterers, both recent college graduates, were subjected to regional cerebral blood flow measurements while attempting to read aloud. Each one received two measurements, one of which was under the influence of haloperidol, 3 mg daily. Both subjects showed improvement on medication, allowing a stuttering versus essentially no stuttering comparisons for each subject. Both subjects showed higher Broca's area flow in the right compared to the left hemisphere, during stuttering. Both showed higher Wernicke's area flow in the left compared to the right hemisphere, however, during stuttering. During reading aloud without stuttering, however, the Brocas's area flows were reversed, now showing a left hemisphere advantage. The results were interpreted as consistent with H. M. Sussman and P. F. MacNeilage's (1975, Neuropsychologia, 13, 19–26) proposal that stutterers exhibit conventional left cerebral dominance for speech reception, but inadequate left cerebral dominance for speech production.     

伍德对胡萨米:马克思和正义问题之争

伍德与胡萨米关于马克思是否批判资本主义为不正义之争是一场富有启发性的论争。本文从三个方面对这场论争做了简要的述评：(1)马克思批判资本主义社会是否基于某种正义观?(2)马克思是否认为资本主义剥削是不正义的?(3)在马克思的视野中,共产主义是否是一个正义社会?     

Access to attitude-relevant information in memory as a determinant of persuasion: The role of message attributes

Recipients with access to attitude-relevant information in memory were thought to draw on these beliefs and prior experiences to evaluate the validity of message arguments. Consistent with this idea, persuasion for these recipients was largely a function of the perceived validity of message content: Messages containing high-quality arguments were more persuasive than messages containing lowquality arguments, whereas variations in a structural attribute of the message (its length) proved to have little impact on opinion change. In contrast, people who tend to retrieve little attitude-relevant information were believed to be less able to evaluate the validity of message arguments in terms of information accessed from memory. Instead, it was anticipated that they would base their opinion judgments on a more superficial analysis of persuasion cues, focusing on attributes like message length. Consistent with this reasoning, these recipients were more persuaded by long than short messages. Recipients with moderate levels of retrieval functioned much like the high-retrieval subjects.     

A mental-health locus of control scale

The purpose of this study was to develop and seek initial validation of a mental- health locus of control scale. Twenty-six mental-health professionals rated each of the 14 statements of a previously-designed mental-health service request form along a 5-point locus of control scale. Six of the 14 items met the study's criteria for inclusion in the mental-health locus of control scale. Discriminant validity of the scale was provided by a study demonstrating that psychotic patients were more external in their perceived locus of control than were a nonpsychotic patient comparison group. Other validation studies and research are suggested.