内侧前额皮层-伏隔核环路在决策冲动中的作用：基于动物模型的研究

注意缺陷多动障碍(attentiondeficit/hyperactivitydisorder,ADHD)行为控制不足与决策冲动密切相关,后者受内侧前额皮层(medial prefrontal cortex, mPFC)与伏隔核(nucleus accumbens, NAc)调节。为调查ADHD决策冲动与m PFC-NAc间功能耦合的关系,研究采用ADHD模型SHR (spontaneously hypertensive rat, SHR)大鼠,结合延迟折扣任务和在体电生理,研究发现,与对照Wistar (WIS)大鼠相比, SHR大鼠对延迟大奖赏的选择百分比降低; WIS大鼠m PFC-NAc的Theta频段相干值表现为延迟选择时显著大于立即选择时、首次选择时大于连续选择时、转换试次时大于连续试次时,而SHR大鼠在上述条件均低于WIS大鼠。回归分析发现m PFC-NAc的相干差值与延迟大奖赏选择率显著正相关。结果表明m PFC-NAc间功能联系减弱是ADHD决策冲动缺陷的重要环路基础,该缺陷与其深度信息加工以及策略转换能力受损有关,扩展了ADHD决策冲动的认知和神经机制的认识。     

Refuting the unfolding-argument on the irrelevance of causal structure to consciousness

The unfolding argument (UA) was advanced as a refutation of prominent theories, which posit that phenomenal experience is determined by patterns of neural activation in a recurrent (neural) network (RN) structure. The argument is based on the statement that any input–output function of an RN can be approximated by an “equivalent” feedforward-network (FFN). According to UA, if consciousness depends on causal structure, its presence is unfalsifiable (thus non-scientific), as an equivalent FFN structure is behaviorally indistinguishable with regards to any behavioral test. Here I refute UA by appealing to computational theory and cognitive-neuroscience. I argue that a robust functional equivalence between FFN and RN is not supported by the mathematical work on the Universal Approximator theorem, and is also unlikely to hold, as a conjecture, given data in cognitive neuroscience; I argue that an equivalence of RN and FFN can only apply to static functions between input/output layers and not to the temporal patterns or to the network’s reactions to structural perturbations. Finally, I review data indicating that consciousness has functional characteristics, such as a flexible control of behavior, and that cognitive/brain dynamics reveal interacting top-down and bottom-up processes, which are necessary for the mediation of such control processes.     

Investigating temporal variations in pedestrian crossing behavior at semi-controlled crosswalks: A Bayesian multilevel modeling approach

“Semi-controlled” crosswalks are unsignalized, but have clear pavement markings and “yield to pedestrian” signs. At these locations, pedestrians and motorists frequently interact to determine who should proceed first. When interacting with drivers, pedestrian crossing decisions are complex events that involve a variety of human responses, as well as vehicle dynamics, traffic characteristics, and environmental conditions. In addition, these complexities can be subject to temporal effects. Without considering temporal variations in pedestrian-motorist interaction, statistical methods could lead to biased coefficient estimates and inaccurate conclusions.The study developed a Bayesian multilevel logistic regression (BMLR) model to capture heterogeneities in pedestrian interaction behavior during four different time periods. The proposed method incorporates time-specific effects that vary randomly between time-periods based on a weakly informative prior. The results indicate significant factors, some of which confirm previous research and some that are new ways to explain pedestrian behavior at the individual level. The identification of variables such as FlowOn and FlowWait sheds light on the interactions between pedestrians – providing more information than the single GroupSize measure.Some consequent safety implications are discussed from the perspectives of vehicle dynamics, vehicle flow rate and pedestrian volume. The more detailed metrics developed in this paper will provide a valuable starting point. for the design of crosswalk controls that will foster a higher degree of compliance and less delay.     

A two-part evaluation approach for measuring the usability and user experience of an Augmented Reality-based assistance system to support the temporal coordination of spatially dispersed teams

One key predictor of team performance and productivity is the teams’ ability to coordinate its subtasks as precisely as possible over time. Thereby, the quality of the temporal coordination in teams is highly dependent on several cognitive team skills, like for instance the ability to build a precise and stable mental model of the situation (shared situation awareness) and of the team task process (task state awareness/ TSA). To support these cognitive skills in teams, various methods and trainings already exist. However, considering teams that work de-located, the prerequisites and therefore the requirements for team supportive methods change. This work presents the results of an empirical usability and user experience (UX) study of an interface for an Augmented Reality-based assistance system for spatially dispersed teams, called Ambient Awareness Tool (AAT). The AAT interface consists of graphical information about the teamwork process and aims at enhancing the TSA of the team, thereby supporting its temporal coordination. Within the framework of a participatory design process we conducted a two-part expert-user-study, comprising a laboratory experiment for the evaluation of the interface usability and a follow-up online survey to additionally investigate the UX. By means of the usability scores we first inferred three interface configuration clusters. A subsequent UX evaluation then allowed us to designate the configuration cluster with the highest usability and UX scores. As a result, we defined one interface configuration that will be investigated concerning its actual impact on the temporal coordination of spatially dispersed teams in a further study.     

Timing the “magical number seven”: Presentation rate and regularity affect verbal working memory performance

The informative value of time and temporal structure often remains neglected in cognitive assessments. However, next to information about stimulus identity we can exploit temporal ordering principles, such as regularity, periodicity, or grouping to generate predictions about the timing of future events. Such predictions may improve cognitive performance by optimising adaptation to dynamic stimuli. Here, we investigated the influence of temporal structure on verbal working memory by assessing immediate recall performance for aurally presented digit sequences (forward digit span) as a function of standard (1000 ms stimulus-onset-asynchronies, SOAs), short (700 ms), long (1300 ms) and mixed (700–1300 ms) stimulus timing during the presentation phase. Participant's digit spans were lower for short and mixed SOA presentation relative to standard SOAs. This confirms an impact of temporal structure on the classic “magical number seven,” suggesting that working memory performance can in part be regulated through the systematic application of temporal ordering principles.     

Psychometric adaption of the impulsive driver behavior scale in a Chinese sample

Impulsivity plays an important role in aberrant driving behavior and crash involvement. The purpose of this study was to evaluate the reliability and validity of the Impulsive Driver Behavior Scale (IDBS, Bıçaksız & Özkan, 2016a) with a Chinese sample. Two hundred and ninety-nine drivers completed the Chinese version of the Impulsive Driver Behavior Scale, the Driver Behavior Questionnaire, the Big Five Inventory and some social-demographic and traffic violation items. A confirmatory factor analysis indicated that a four-factor solution with 20 items yielded a better fit to the data than other solutions. The reduced IDBS showed good reliability and a stable structure. Drivers’ functional impulsivity was positively correlated with positive driver behavior and some ordinary violations. Meanwhile, the other three dimensions of dysfunctional impulsivity showed negative correlations with positive driver behavior and positive associations with aberrant driving behavior and penalty points and fines. Impulsive driver behavior is also associated with agreeableness and conscientiousness. These results provide evidence supporting the IDBS as a reliable and valuable instrument for measuring driving impulsivity in the Chinese traffic environment.     

Is inhibition of return a reflexive effect?

The inhibition of return (IOR) phenomenon is routinely considered an effect of reflexive attention because the paradigm used to generate IOR employs peripheral cues that are uninformative as to where a target will appear. Because the cues are spatially unreliable it is thought that there is no reason for attention to be committed volitionally to them, and hence, the IOR effect is considered reflexive. What has been generally overlooked, however, is that the cues provide reliable temporal information as to when a target will occur. This predictive information is used by participants to prepare volitionally for when a target is likely to appear. We investigated whether the IOR effect is a product of the volitional application of attention to peripheral cues for the use of their temporal information. To test this idea we rendered the temporal information provided by peripheral cues unreliable. While this eliminated participants using the cues volitionally, it did not abolish the IOR phenomenon. These data demonstrate two new findings. First, the IOR effect is fundamentally a reflexive phenomenon. Second, when peripheral cues are not used volitionally, the IOR effect is attenuated. Together, the present findings indicate that the IOR effect can be modulated by volitional (top-down) processes but it is not the product of them. We argue that an intimate link between fronto-parietal regions and the superior colliculus provide a functional neural mechanism for this volitional effect to impact IOR.     

Measuring Impulsivity in School-Aged Boys and Examining Its Relationship with ADHD and ODD Ratings

Seven different laboratory measures of impulsivity were administered to a group of 165 school-aged boys. Parents' and teachers' ratings of Attention Deficit and Hyperactivity Disorder and Oppositional/Defiant Disorder were also obtained. Factor analyses of impulsivity measures revealed the existence of a strong Inhibitory Control Factor including measures derived from Stop Task, the Continuous Performance Test, the Matching Familiar Figures Test, and the Circle Tracing Task. Other forms of impulsivity like resistance to interference, the Wisconsin Card Sorting Test and efficiency in the DRL Task loaded on a second independent factor. The Inhibitory Control factor was correlated with ADHD ratings, whereas the second factor was slightly related to the presence of ODD symptoms. Discussion is focused on the relevance of inhibitory control in impulsivity and ADHD research.