Deep dyslexia in childhood?

Deep dyslexia is an acquired reading disorder in which semantic substitutions (e.g., city read as town) are made in reading single isolated words. In this paper, evidence for deep dyslexic-type errors is presented from the word-recognition responses of six children, aged 7 years and 0 month to 8 years and 9 months, with severe reading disorders. These semantic substitutions occur in the absence of phonological skills. Therefore, it appears that there exists a small subset of developmental dyslexics who at the beginning of acquisition of reading skills are able to engage in semantic processing, but who show severe impairment of phonological processing. The existence of these reading errors indicate that the use of a phonological code is not necessary to extract meaning from the printed word.     

A study of some conditions relating to the retarded adult's stereotyped responding in a binary-choice task

This study was a longitudinal one that examined the effects of certain conditions on alternation and perseveration in a binary-choice task. The conditions manipulated included: (1) lapse of time (stability of the pattern), (2) stimulus dissimilarity, (3) spatial location of the two alternatives, (4) time-out (time away from the task), (5) delay between responses, and (6) differential reinforcement of the two choices. Eight mentally retarded adults, identified as “pure” alternaters or perseveraters, served as subjects. Perseveration was “disrupted” only by differential reinforcement. Alternation was affected by all experimental manipulations with the exception of stimulus dissimilarity.     

Developmental differences in cognitive mapping: Configurational knowledge of familiar large-scale environments

In order to investigate the development of cognitive mapping of familiar large-scale environments. First-, fifth-, and eighth-grade children were asked to make bearing and distance estimates to six targets from three sighting locations in their school. Correlations between estimated and actual bearings and distances were extremely high at all grade levels, indicating that (a) children at all grade levels could reliably make such estimates, and (b) route knowledge of even the youngest children was quite high. Bearing accuracy increased between first- and fifth-grade and showed little improvement thereafter. Increases in a measure of configurational accuracy were found between first- and fifth-grade and between fifth- and eighth-grade. Differential accuracy as a function of the demands of particular sighting locations was found only for the younger children.     

fMRI responses to Jung's Word Association Test: implications for theory,treatment and research

Jung's Word Association Test was performed under fMRI conditions by 12 normal subjects. Pooled complexed responses were contrasted against pooled neutral ones. The fMRI activation pattern of this generic ‘complexed response’ was very strong (corrected Z scores ranging from 4.90 to 5.69). The activation pattern in each hemisphere includes mirror neurone areas that track ‘otherness’ (perspectival empathy), anterior insula (both self‐awareness and emotional empathy), and cingulated gyrus (self‐awareness and conflict‐monitoring). These are the sites described by Siegel and colleagues as the ‘resonance circuitry’ in the brain which is central to mindfulness (awareness of self) and empathy (sense of the other), negotiations between self awareness and the ‘internal other’. But there is also an interhemispheric dialogue. Within 3 seconds, the left hemisphere over‐rides the right (at least in our normal subjects). Mindfulness and empathy are central to good psychotherapy, and complexes can be windows of opportunity if left‐brain hegemony is resisted. This study sets foundations for further research: (i) QEEG studies (with their finer temporal resolution) of complexed responses in normal subjects (ii) QEEG and fMRI studies of complexed responses in other conditions, like schizophrenia, PTSD, disorders of self organization.     

Extinction of morphine analgesic tolerance

It has been suggested that the analgesic effect of morphine becomes attenuated over the course of successive administrations by a conditional, compensatory, hyperalgesic response elicited by the administration procedure, thus accounting (in part) for analgesic tolerance. On the basis of this associative model of tolerance, it would be predicted that established tolerance would be extinguished by placebo sessions. In experiments of apparently similar design (but conducted by different experimenters in different laboratories), data both confirming and refuting this prediction have previously been published. The present experiment, conducted jointly by the experimenters who reported the divergent findings, was designed to determine the reasons for the different results. It was found that placebo sessions do consistently attenuate morphine analgesic tolerance. Such extinction is not limited to the experimenter, drug preparation, rat strain, or apparatus used in the original, successful demonstration of the phenomenon, but rather is also demonstrable under conditions similar to those used in subsequent experiments which failed to demonstrate extinction of tolerance. Results of the present experiment suggest that the failures to demonstrate extinction of tolerance were attributable to insufficient extinction training.     

The use of the cumulative rehearsal strategy: A developmental study

This study was designed to address two issues: (1) At what age do children spontaneously use a cumulative rehearsal strategy; and (2) What effect does the use of the strategy have on their performance?Twenty-eight children at each of five grade levels (nursery, kindergarten, 1, 3, and 5) were tested in a serial-position recall task. Stimuli were pictures of common objects and animals whose labels were one or two syllables in length. Following testing, the children were asked to report the memory strategy they had used.The assumption was made that children who were using a cumulative rehearsal strategy would perform better on series of one-syllable items than on series of two-syllable items. As predicted, nursery, kindergarten, and first-grade subjects correctly recalled as many two-syllable as one-syllable items: Both third- and fifth-graders recalled significantly more one-syllable than two-syllable items. Results indicated that (1) young children do not spontaneously use a cumulative rehearsal strategy until after first grade, and (2) the use of rehearsal did not facilitate overall performance of the rehearsers relative to the nonrehearsers at any grade level. Results are discussed in terms of their theoretical implications for the study of memory development.