Renewal of cue-elicited urge to smoke: implications for cue exposure treatment

The effects of cue exposure therapy are limited, because renewal after extinction is an important source of relapse. In this study, 33 smokers were exposed to a cue predicting smoking availability and a cue predicting smoking unavailability in one context (acquisition context A). Following extinction in another context (extinction context B), a test for renewal took place in the original acquisition context A (i.e. ABA renewal). Urge to smoke was measured using a Visual Analogue Scale. Renewal of differential conditioned urge responding occurred when participants were tested in the acquisition context, while differential urge responding remained extinguished when tested in the extinction context. This experiment provides evidence that ABA renewal occurred in smokers. Clinical implications are discussed.     

Within-subject renewal in sign tracking

Three sign-tracking experiments using pigeon subjects examined the contextual dependence of extinction after conditioning. Renewal of extinguished responding occurred when testing occurred in a different context, using a variety of different renewal designs. In each case, a within-subject design ensured that the various contexts were equivalent in their general treatment histories and differed only in whether or not a particular stimulus had been extinguished in their presence. These results strengthen the view that extinction is relatively context specific.     

Dissociations among ABA, ABC, and AAB recovery effects

In a human predictive learning experiment, the strengths of ABA, ABC, and AAB recovery effects after discrimination reversal learning were compared. Initially, a discrimination between two stimuli (X+, Y−) was trained in Context A. During Phase 2, participants received discrimination reversal training (X−, Y+) either in Context A (Group AAB) or in Context B (Group ABA, Group ABC). Testing occurred in the reversal context and in a neutral context (Group AAB, Group ABC) or in the reversal context and in the acquisition context (Group ABA). Recovery effects were similar in ABA and ABC procedures, whereas no AAB recovery effect occurred. Furthermore, the rate of discrimination reversal learning during Phase 2 was unaffected by whether training was conducted in the same or in a different context as initial learning. Results indicate that contextual stimuli are processed before interfering information is presented. These representations, however, do not acquire the ability to control performance.     

“For a New World”: On the practical impulse of Husserlian theory

The thesis of this article is that in Husserlian phenomenology there is no opposition between theory and praxis. On the contrary, he understands the former to serve the latter, so as to usher in a new world. The means for doing is the phenomenological reduction or epoché. It gives the phenomenologist access to the starting point, the “first things,” and orients his/her striving towards reason and the renewal of humanity. Careful attention to the significance of the epoché also sheds light on Husserl’s understanding of the relationship of phenomenology not only to philosophy but also to the other sciences. Though an exposition of the “phenomenology of the philosophical vocation” which Husserl sketched in the 1920s, e.g., in his Kaizo articles and lectures on first philosophy, the author seeks to shore up his thesis. For Walter Biemel     

The resistance of renewal to instructions that devalue the role of contextual cues in a conditioned suppression task with humans

The renewal of extinguished conditioned behaviour appears to reflect context-dependent learning. The present research used a conditioned suppression task with humans to examine whether instructions concerning the context could influence renewal. Pairings of a conditional stimulus (CS) and unconditional stimulus (US) were made in one context, followed by extinction trials of CS alone in a second context, and test trials of CS alone upon return to the original learning context. Four experiments tested whether the renewal of conditioned suppression observed during test would be attenuated if participants were instructed that the context changes were irrelevant to the predictive relationship between the CS and US. Using a differential conditioning design, no attenuation was found when the instructions were given prior to conditioning (Experiment 1) or immediately prior to the test trials (Experiment 2). The latter result was replicated with a single-cue conditioning design and further controls for exposure to the extinction contexts (Experiment 3). The collection of on-line ratings about the relationship between the contextual changes and the predictive nature of the CS indicated that participants did attend to and believe the instructions (Experiment 4). The results point to the resistance of renewal to explicit instructions that attempt to devalue the role of the contextual cues.     

Stronger renewal in human fear conditioning when tested with an acquisition retrieval cue than with an extinction retrieval cue

It was previously demonstrated in our laboratory that conditioned fear in humans can renew after extinction, when this procedure took place in a different context (ABA-renewal [Vansteenwegen et al. (2005). Return of fear in a human differential conditioning paradigm caused by a return to the original acquisition context. Behaviour Research and Therapy, 43(3), 323–336]). Using the same experimental design, we now tested the power of retrieval cues to interact with this contextual renewal phenomenon. Two groups went through acquisition and extinction (in a different context). They were then tested in the original acquisition context and in the presence of a retrieval cue. In the acquisition-cue group, this cue previously featured during the acquisition procedure; in the extinction-cue group, the cue previously featured during the extinction procedure. As expected, renewal of conditioned electro-dermal responding and retrospective expectancy ratings was strongest in the acquisition-cue group. Theoretical and clinical implications of this finding are discussed.     

Survival of the partial reinforcement extinction effect after contextual shifts

The effects of contextual shifts on the partial reinforcement extinction effect (PREE) were studied in autoshaping with rats. Experiment 1 established that the two contexts used subsequently were easily discriminable and equally salient. In Experiment 2, independent groups of rats received acquisition training under partial reinforcement (PRF) or continuous reinforcement (CRF). Significant PREEs were observed whether extinction occurred in the same or in a different context. In Experiment 3, after PRF or CRF acquisition training, each group received extinction of the same conditioned stimulus in both the same and different contexts. PREEs were observed under both conditions, although extinction was accelerated after a contextual shift. These results were discussed in relation to the role of mediational states in the PREE.     

Conditioned craving cues elicit an automatic approach tendency

In two experiments, we used a Pavlovian differential conditioning procedure to induce craving for chocolate. As a result of repeated pairing with chocolate intake, initially neutral cues came to elicit an automatic approach tendency in a speeded stimulus-response compatibility reaction time task. This automatic approach tendency, moreover, seemed to be sensitive to manipulations of extinction and renewal in the Pavlovian conditioning procedure. These findings corroborate and extend previous reports of automatic approach tendencies elicited by substance-relevant cues in addiction, while controlling for alternative accounts for such observations. Moreover, our data lend support to and extend learning models of cue-induced craving and addiction. Finally, we argue that the procedure we present here provides an ecologically valid behavioural tool that allows studying processes involved in cue-induced craving, addiction and relapse without relying on verbal report.     

All we need is a cue to remember: the effect of an extinction cue on renewal

In the present study, it was investigated by employing a human fear conditioning paradigm whether an extinction retrieval cue can attenuate renewal of conditioned responding after an extinction treatment procedure, and if so, what the precise role of such an extinction cue comprises. It was hypothesized that such a cue can attenuate renewal and would function as a safety signal capable of directly inhibiting the expectancy of an aversive outcome and conditioned skin conductance responding to a conditioned stimulus. The results demonstrated that the extinguished expectancy of an aversive outcome was renewed when the CS was presented outside the extinction context and that an extinction cue attenuated this effect. This extinction cue, however, only transferred its inhibitory properties to other, non-extinguished stimuli when there was no contextual switch. This safety signal function was not observed after a switch in context. Possible functions of the extinction cue and its application in extinction-based exposure treatments are discussed.     

Role of context similarity in ABA, ABC, and AAB renewal paradigms: Implications for theories of renewal and for treating human phobias

Using barpress conditioned suppression, we studied the renewal of conditioned fear in rats, an animal model for the relapse of human fears and phobias. We demonstrated ABA renewal when the only differences between Contexts A and B included (1) their odor, (2) their location (i.e., side of room), and (3) unintended differences between copies of the same box at the two sites. Removing either the odor or location cues abolished the renewal effect. We then directly compared the effects of ABA and AAB procedures under two levels of context similarity. Although AAB renewal occurred, ABA renewal was stronger. Adding multiple context distinctions to the three listed above did not significantly enhance either form of renewal. Finally, we directly compared the strengths of AAB, ABC, and ABA renewal. AAB renewal, though again significant, was weaker than ABA and ABC renewal, which did not differ significantly. Fear renewal (relapse) can thus be reduced by extinguishing the fear in the acquisition context, regardless of the nature of the test context.