Sensitivity to lexical denotation and connotation in brain-damaged patients: A double dissociation?

Sets of words can be grouped in terms of their denotation (cold and warm both refer literally to temperature) or in terms of their connotation (cold and warm connote remoteness and intimacy, respectively). To assess whether these two facets of meaning are dissociable, unilaterally left- and right-hemisphere-damaged patients were presented with word triads and asked to group together the two words that were closest in meaning. Right-hemisphere-damaged patients showed a preserved sensitivity to denotation, and a selective insensitivity to connotative facets of meanings. In contrast, left-hemisphere-damaged patients exhibited a preserved sensitivity to connotation as well as a selective insensitivity to denotative aspects of meanings. Inasmuch as normal control subjects displayed a flexible sensitivity to both denotative and connotative aspects of meaning, the results suggest that unilateral brain damage selectively curtails use of one or the other major aspect of word meaning.     

The nature of the phonological disorder in conduction aphasia

Sequences of attempts to name pictured objects were used to examine phonological dysfunction in three diagnostic subgroups of aphasia. A prevalence of "phonologically-oriented sequences" (i.e., those sequences that contained only attempts with a phonological resemblance to the target word) was found to be a diagnostic criterion for conduction aphasia. When compared to a group of Broca's (n = 7) and Wernicke's (n = 5) aphasics, all the conduction aphasics (n = 6) produced proportionately more of such phonologically-oriented sequences on a picture naming test. An examination of the phonologically-oriented sequences produced by the conduction aphasics indicates that speech production in conduction aphasia involves dysfunction at an early stage of sound-encoding. The theoretical implications of this view are discussed.     

Aphasics' selective deficits in appreciating grammatical agreements

This study attempted to dissociate in aphasic patients different aspects of grammatical capacity. Subjects were asked to evaluate sentences containing violations of agreements between pronouns and verbs. Agreements which are considered primarily structural in nature were violated (e.g., a surface object case like “them” placed in a surface subject sentential slot) while other violated agreements seemed to involve both structural and semantic information (e.g., lack of agreement between a pronoun and a verb in terms of the number of people performing the act). These violations were couched in one of three types of sentential frames which varied in terms of syntactic complexity (e.g., active declarative vs. passive syntactic voices). The results revealed that Broca's aphasics found agreement violations difficult to detect in complex syntactic frames. They were quite successful at detecting even violations of the largely structural “case” type of agreement, however, when couched in simpler syntactic frames. Fluent aphasics encountered more difficulty detecting violations of agreements involving both semantic and structural information than agreements which were primarily structural in nature, that is, regardless of the syntactic frame. These unique performance profiles suggest that Broca's aphasics may be agrammatic only with respect to certain aspects of a sentence's structure, and that fluent aphasics may also experience some selective—but different—grammatical deficits.     

The effect of syntactic encoding on sentence comprehension in aphasia.

This study compared two levels of syntactic encoding with respect to their effect on aphasics' auditory comprehension. The same informational content was presented either as an embedded sentence or as two contiguous simplé propositions. A similar contrast was utilized to compare sentences containing relational terms of time, comparison, instrumentality, as well as sentences involving conjunction reduction, with parallel messages expressed in expanded, simplified form. A picture-verification paradigm was used. Comprehension was significantly enhanced only in the case of embedded sentences, with a tendency for Broca's aphasics to show the maximum effects.     

Choice times and Spence's discrimination learning theory

In two experiments, rats acquired brightness discriminations in a free-operant circular runway with two response alternatives. Both individual and group choice times revealed continuous changes that were not apparent in the discrete measure of choice. Two major assumptions of Spence's discrimination learning theory were confirmed: (a) learning is continuous, and (b) discriminative stimuli in simple discrimination tasks of both simultaneous and successive types are compounds with position elements as well as elements from the relevant visual dimension. The distinctive, consistent pattern of learning revealed by the choice-time measure suggests that position habits reflect a learning strategy in which the complex task is learned as a series of simpler ones.     

Repetition in the transcortical aphasias

Transcortical aphasic patients were assessed on a repetition task comprised of both well-formed and deviant sentences. The patients faithfully repeated those sentences that were factually incorrect but grammatically well formed, and those sentences that were ungrammatical because of selection restriction violations. In contrast, presented with sentences featuring only minor syntactic violations (e.g., lack of number agreement), the patients spontaneously, and without awareness, resisted exact repetition; moreover, the resultant changes most often served to correct the syntactic deviations. Repetitions of sentences of this latter type also revealed a difference between the patients as a function of level of comprehension. The transcortical motor aphasic patient was influenced by semantic factors in his alterations of the minor syntactic violations, while the transcortical sensory aphasic was not. These findings are discussed in relation to the notion of autonomous syntactic processing. They are taken to suggest that syntactic facts such as number agreement are represented at a level in the processing chain that is distinct from that of semantic representation.     

Aphasia type and aging

We analyzed the relationship between age and clinical type of aphasia in 167 right-handed men who had suffered cerebrovascular accidents. Patients with unequivocal diagnoses as Broca's, Wernicke's, anomic, conduction, and global aphasics were considered. The median age of the Broca's group (51 years old) was significantly lower than that of the total group (55.8 years old), while the median age of the Wernicke's group was significantly higher (63 years old). Moreover the incidence of Wernicke's aphasia increased steadily with age, while incidence of the other types of aphasia peaked in the sixth decade and then diminished with increasing age.     

Dichhaptic hand-order effects with verbal and nonverbal tactile stimulation

The palms of normal right-handed subjects were stimulated dichhaptically, i.e., with competing, bimanually presented tactile stimuli consisting of pairs of letters, pairs of digits, or pairs of line orientations. The subjects were required to identify both stimuli in a particular order, and order of report was compared between hands and across stimulus materials. Results indicated right-hand superiority for letters and left-hand superiority for lines; no hand differences occurred for digits. However, observed differences between hands appeared with second reports only, suggesting that measures of tactile storage are more sensitive to laterality differences than measures closer in time to actual stimulation.