Elevated responding to safe conditions as a specific risk factor for anxiety versus depressive disorders: evidence from a longitudinal investigation

The current study evaluated the degree to which startle reflexes (SRs) in safe conditions versus danger conditions were predictive of the onset of anxiety disorders. Specificity of these effects to anxiety disorders was evaluated in comparison to unipolar depressive disorders and with consideration of level of neuroticism. A startle paradigm was administered at baseline to 132 nondisordered adolescents as part of a longitudinal study examining risk factors for emotional disorders. Participants underwent a repetition of eight safe-danger sequences and were told that delivery of an aversive stimulus leading to a muscle contraction of the arm would occur only in the late part of danger conditions. One aversive stimulus occurred midway in the safe-danger sequences. Participants were assessed for the onset of anxiety and unipolar depressive disorders annually over the next 3 to 4 years. Larger SR magnitude during safe conditions following delivery of the aversive stimulus predicted the subsequent first onset of anxiety disorders. Moreover, prediction of the onset of anxiety disorders remained significant above and beyond the effects of comorbid unipolar depression, neuroticism, and subjective ratings of intensity of the aversive stimulus. In sum, elevated responding to safe conditions following an aversive stimulus appears to be a specific, prospective risk factor for the first onset of anxiety disorders.     

A latent variable model approach to estimating systematic bias in the oversampling method

The method of oversampling data from a preselected range of a variable’s distribution is often applied by researchers who wish to study rare outcomes without substantially increasing sample size. Despite frequent use, however, it is not known whether this method introduces statistical bias due to disproportionate representation of a particular range of data. The present study employed simulated data sets to examine how oversampling introduces systematic bias in effect size estimates (of the relationship between oversampled predictor variables and the outcome variable), as compared with estimates based on a random sample. In general, results indicated that increased oversampling was associated with a decrease in the absolute value of effect size estimates. Critically, however, the actual magnitude of this decrease in effect size estimates was nominal. This finding thus provides the first evidence that the use of the oversampling method does not systematically bias results to a degree that would typically impact results in behavioral research. Examining the effect of sample size on oversampling yielded an additional important finding: For smaller samples, the use of oversampling may be necessary to avoid spuriously inflated effect sizes, which can arise when the number of predictor variables and rare outcomes is comparable.     

The relationship between anxiety sensitivity and latent symptoms of emotional problems: A structural equation modeling approach

A large body of research suggests that common and specific psychopathology dimensions underlie the symptoms that occur within mood and anxiety disorders. As of yet, it is unclear precisely how the facets of Anxiety Sensitivity (AS), or fear of the symptoms of fear and anxiety, relate to these latent factors. Using data from 606 adolescents participating in the baseline phase of a longitudinal study on risk factors for emotional disorders, we modeled the facets of AS as measured by the Anxiety Sensitivity Index-Expanded Form (ASI-X) and related these facets to a hierarchical model of latent symptoms of psychological distress. Results suggest that one facet of AS is associated with a broad General Distress factor underlying symptoms of most emotional disorders while others relate to intermediate-level and conceptually-meaningful narrow factors representing aspects of psychological distress specific to particular emotional disorders.     

Examining the long-term stability of overgeneral autobiographical memory

Overgeneral autobiographical memory (OGM) is a proposed trait-marker for vulnerability to depression, but relatively little work has examined its long-term stability. This study investigated the stability of OGM over several years in 271 late adolescents and young adults participating in a larger longitudinal study of risk for emotional disorders. The Autobiographical Memory Test (AMT) was administered twice, with test–retest intervals ranging from approximately 3 to 6 years. There was evidence of significant but modest stability in OGM over several years. Specifically, Spearman rank correlations (ρs) between the proportions of specific and categoric memories generated on the two AMTs were .31 and .32, respectively. We did not find evidence that the stability of OGM was moderated by the length of the test–retest interval. Furthermore, the stability coefficients for OGM for individuals with and without a lifetime history of major depressive disorder (MDD) were relatively similar in magnitude and not significantly different from one another (ρs=.34 and .42 for the proportions of specific and categoric memories for those with a history of MDD; ρs=.31 for both the proportions of specific and categoric memories for those without a history of MDD). Implications for the conceptualisation of OGM are discussed.     

Evaluating the Invariance of the Factor Structure of the EPQ–R–N Among Adolescents

We examined the factor structure of the Neuroticism scale of the Eysenck Personality Questionnaire (EPQ–R–N; S. B. G. Eysenck, Eysenck & Barrett, 1985) and its factor invariance across sex and racial/ethnic groups in a sample of 1,979 adolescents. Using confirmatory factor analyses, we compared a hierarchical model to previous models of the EPQ–R–N and to single-factor and 3-factor structures. The hierarchical factor structure in which a general factor coexists with 3 group factors (depression, social concerns, and worry) was superior to alternative models. The general factor accounted for more than 60% of the variance in EPQ–R–N total scores and was invariant across sex and ethnicity. The 3 group factors varied across ethnicity and sex. We discuss the implications of these findings for conceptualization and assessment of neuroticism using the EPQ–R–N.     

Overgeneral autobiographical memory and chronic interpersonal stress as predictors of the course of depression in adolescents

This study investigated whether overgeneral autobiographical memory (OGM) predicts the course of depression in adolescents. As part of a larger longitudinal study of risk for emotional disorders, 55 adolescents with a past history of major depressive disorder or minor depressive disorder completed the Autobiographical Memory Test. Fewer specific memories predicted the subsequent onset of a major depressive episode (MDE) over a 16-month follow-up period, even when covarying baseline depressive symptoms. This main effect was qualified by an interaction between specific memories and chronic interpersonal stress: Fewer specific memories predicted greater risk of MDE onset over follow-up at high (but not low) levels of chronic interpersonal stress. Thus, our findings suggest that OGM, in interaction with chronic interpersonal stress, predicts the course of depression among adolescents, and highlight the importance of measuring interpersonal stress in OGM research.     

Dyadic predictors of outcome in a cognitive-behavioral program for patients with generalized anxiety disorder in committed relationships: a "spoonful of sugar" and a dose of non-hostile criticism may help

The present study tested whether pre-treatment levels of partner hostility and non-hostile criticism predicted outcome in an individual cognitive-behavioral therapy package for generalized anxiety disorder (GAD). Eighteen patients with a principal or co-principal diagnosis of GAD were randomly allocated to a treatment condition (n=8) or a delayed treatment condition (n=10). In addition, the patients and their partners were videotaped discussing the patients’ worries. These videotapes were later coded for levels of partner hostility and non-hostile criticism directed at the patients. Treatment resulted in statistically and clinically significant change at post-test. Finally, partner hostility predicted worse end-state functioning whereas partner non-hostile criticism predicted better end-state functioning.     

Coefficients Alpha,Beta, Omega,and the glb: Comments on Sijtsma

There are three fundamental problems in Sijtsma (Psychometrika, 2008): (1) contrary to the name, the glb is not the greatest lower bound of reliability but rather is systematically less than ω _t (McDonald, Test theory: A unified treatment, Erlbaum, Hillsdale, 1999), (2) we agree with Sijtsma that when considering how well a test measures one concept, α is not appropriate, but recommend ω _t rather than the glb, and (3) the end user needs procedures that are readily available in open source software.     

Evaluating the invariance and validity of the structure of dysfunctional attitudes in an adolescent population

Form A of the Dysfunctional Attitude Scale (DAS-A), a self-report measure of depressive beliefs, is widely used to test Beck's cognitive model of depression. The present study is the first to evaluate the DAS-A factor structure in an adolescent population of 542 high school juniors and the first to examine a hierarchical model. Findings support the existence of a hierarchical structure consisting of two conceptually meaningful group factors (Dysfunctional Attitudes About Achievement and Dysfunctional Attitudes About Needing Approval), a method factor consisting of reverse-worded items, and a general factor, which accounts for 65% of the variance in total scores. The general factor is related to sociotropy, autonomy, and neuroticism, whereas the Dysfunctional Attitudes About Achievement and Dysfunctional Attitudes About Needing Approval factors demonstrate convergent and discriminant validity with respect to autonomy and sociotropy. The structure displays partial metric invariance in female and male students as well as in Caucasian and Non-Caucasian students.