The relationship of affiliative arousal to dopamine release

Higher levels of affiliation motivation after exposure to affiliative films are significantly related to higher dopamine concentrations in saliva in one study of 61 college students of both sexes, and in plasma in another study of 47 adults of both sexes. Individuals high in dispositionaln Affiliation, if they also reported high life stress, showed high gains in dopamine concentration in plasma after exposure to an affiliative film significantly more often than other individuals. Since aroused affiliation motivation was not associated with higher concentrations of norepinephrine, epinephrine, or cortisol in either study, it appears likely that dopamine is especially associated with arousal of affiliation motivation, just as norepinephrine has been found to be associated with arousal of power motivation. Thus, different motives may be subserved by different hormones, making it unlikely that all motives lead to the same state of physiological arousal.This research was carried out when all the authors were connected with the Department of Psychology and Social Relations at Harvard University. We acknowledge with thanks the support of the John D. and Catherine T. MacArthur Foundation through a grant to the senior author.     

Feeding violence: A reply

Genetic Screening: Ethical Issues, Nuffield Council on Bioethics, 1993, 115 pages, pb £6.00 from Nuffield Foundation, 28 Bedford Sq. London W1.

Draft Convention for the Protection of Human Rights and the Dignity of the Human Being with Regard to the Application of Biology and Medicine: Bioethics Convention and Explanatory Report, DIR/JUR (94) 2, Strasbourg: Council of Europe, July 1994.

UNESCO International Bioethics Committee: Report of the subcommittee on genetic screening and testing, Paris; November 1994.     

Socioeconomic Status and Psychological Function in Children with Chromosome 22q11.2 Deletion Syndrome: Implications for Genetic Counseling

The purpose of this study is to examine the association between parental socio-economic status (SES) and childhood neurocognition and behavior in children with chromosome 22q11.2 deletion syndrome (22q11DS). Although undoubtedly, the deletion of genes in the 22q11.2 interval is primarily responsible for the psychological manifestations, little is known about the role of the environment in either mitigating or contributing to these problems. We examined the association of parental socio-economic status (SES) with cognition and behavior in children with 22q11DS (n = 65) and matched healthy control subjects (n = 52), since SES is a component of family resources. We found that in children with 22q11DS, higher SES correlated with better overall functioning (p < .01) and social skills (p < .01), and less frequent oppositional defiant behavior (p < .001). These findings were in contrast to the control subjects in whom SES correlated with cognition and achievement, but not behavior. Our results indicate that environmental factors influence the behavioral phenotype in children with 22q11DS, providing a framework for developing appropriate interventions. As such, genetic counseling for families with 22q11DS may include consideration of family resources and inclusion of other health professionals, such as social workers, to explore with the family available social supports and resources.     

Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia

Exposure to high altitude is known to cause impairment in cognitive functions in sojourners. The molecular events leading to this behavioral manifestation, however, still remain an enigma. The present study aims at exploring the nature of memory impairment occurring on chronic exposure to hypobaric hypoxia and the possible role of glutamate in mediating it. Increased ionotropic receptor stimulation by glutamate under hypobaric hypoxic conditions could lead to calcium mediated excitotoxic cell death resulting in impaired cognitive functions. Since glutamate is cleared from the synapse by the Glial Glutamate Transporter, upregulation of the transporter can be a good strategy in preventing excitotoxic cell death. Considering previous reports on upregulation of the expression of Glial Glutamate Transporter on ceftriaxone administration, the therapeutic potential of ceftriaxone in ameliorating hypobaric hypoxia induced memory impairment was investigated in male Sprague Dawley rats. Exposure to hypobaric hypoxia equivalent to an altitude of 7600 m for 14 days lead to oxidative stress, chromatin condensation and neuronal degeneration in the hippocampus. This was accompanied by delayed memory retrieval as evident from increased latency and pathlength in Morris Water Maze. Administration of ceftriaxone at a dose of 200 mg/kg for 7 days and 14 days during the exposure on the other hand improved the performance of rats in the water maze along with decreased oxidative stress and enhanced neuronal survival when compared to hypoxic group without drug administration. An increased expression of Glial Glutamate Transporter was also observed following drug administration indicating faster clearance of glutamate from the synapse. The present study not only brings to light the effect of longer duration of exposure to hypobaric hypoxia on the memory functions, but also indicates the pivotal role played by glutamate in mediating excitotoxic neuronal degeneration at high altitude. The therapeutic potential of ceftriaxone in providing neuroprotection in excitotoxic conditions by increasing Glial Glutamate Transporter expression and thereby enhancing glutamate uptake from the synapse has also been explored.     

LOEVINGER'S SENTENCE COMPLETION TEST OF EGO DEVELOPMENT: A USEFUL TOOL FOR CROSS-CULTURAL RESEARCHERS

This study examined the validity of Loevinger's ego development model and method from a cross-cultural perspective. Loevinger's Sentence Completion Test was administered to 171 Australian and 110 Indian tertiary students. The results strongly supported Loevinger's claims for the universality of her model.     

An empirical investigation of Garnets and Pleck's Sex Role Strain Analysis

This study is an empirical investigation of Garnets and Pleck's conceptual analysis — the Sex Role Strain Analysis — which sought to explain the contradictory findings in regard to the relationship between sex role identity and self-esteem. Garnets and Pleck (Sex Role Identity, Androgyny, and Sex Role Transcendence: A Sex Role Strain Analysis, Psychology of Women, 1979, 3(3), 270–283) argued that, while much of previous research assumed that sex role identity has a direct effect on self-esteem, the relationship between the two is actually moderated by the same-sex ideal and sex role salience. This paper adapted the model by considering the effect of sex role salience at the individual and at the cultural levels. More specifically, the revised model was tested within two societies (India and Australia) that differ markedly in the level of sex role salience at the cultural level. The results revealed that sex role salience at the cultural level is an important moderating variable. In the Indian sample, for example, the relationship between sex role ientity and self-esteem is moderated by individual's perception of the sam-sex ideal. In societies (e.g., Australia) that emphasize individuality, however, the relationship between sex role identity and self-esteem is probably moderated by other variables such as individuals' perception of the image that they desire for themselves. The implications of these findings for sex role identity research are discussed.     

Implicit memory for phonological processes in visual stem completion

Four experiments were conducted investigating the role of phonology in repetition priming. Experiment 1 used a cross-modal priming paradigm in which participants made semantic judgments about spoken words and then performed a visual stem completion task. In Experiments 2–4, both the primes and the test stems were presented visually. The results of the first three experiments revealed that priming transfers across interpretations of a homophone. That is, seeing or hearingweek primes bothweek andweak. The results of Experiment 4 showed that homophone priming cannot be attributed to the orthographic similarity of homophonic words. Together, these results indicate that repetition priming on a visual word completion task includes a phonological component.     

Exploring the Impact of Parental Military Deployment/Field Posting on Adolescents in Indian Military Families

The purpose of this study was to explore the consequences of parental deployment for adolescents and to identify the risk and protective factors which may affect their well- being. The study being exploratory in nature, focus group was chosen for data collection. Three focus groups were held with boys and girls in the age group 12–18 years who were experiencing the deployment of their father for more than six months. Each group consisted of 6–8 participants. A semi structured interview schedule was prepared for the focus group interviews. Each focus group was audio taped and then transcribed for further analysis. Response themes indicate relocation in the absence of the father, changes in roles and responsibilities, routine changes, not having the parent to help with the homework, participate in activities and provide guidance as major sources of stress. While the relaxation in family rules and discipline is cherished by all, there are reintegration problems when the parent returns. Some adolescents expressed concern about the health and worries of the at-home parent, for most of them the mother or the at home parent is the central figure who helps steer through the multiple deployments.     

Psychopathology in Children with Thalassemia Major

The present work investigated the prevalence and spectrum of psychopathology in children with thalassemia. Childhood psychopathology measurement schedule (CPMS), adapted from Child Behavior Checklist was administered on children with thalassemia major receiving regular blood transfusion. Age and sex matched children with other chronic illness (bronchial asthma) served as controls. 46.7% of children with thalassemia had a CPMS score of > 10 as against 17.1% in the control group. Children with thalassemia had higher scores in factors of conduct problems, special symptoms and somatization. This study highlights the significantly higher psychopathology in children with thalassemia major and emphasizes the need for psychosocial support during treatment.