Modeling and estimating recall processing capacity: Sensitivity and diagnostic utility in application to mild cognitive impairment

We investigate the potential for using latency-based measures of retrieval processing capacity to assess changes in performance specific to individuals with mild cognitive impairment (MCI), a reliable precursor state to Alzheimer’s Disease. Use of these capacity measures is motivated in part by exploration of the effects of atrophy on a computational model of a basic hippocampal circuit. We use this model to suggest that capacity may be a more sensitive indicator of the underlying atrophy than speed of processing, and test this hypothesis by adapting a standard behavioral measure of memory (the free and cued selective reminding test, FCSRT) to allow for the collection of cued recall latencies. Participants were drawn from five groups: college-aged, middle-aged, healthy elderly, those with a diagnosis of MCI, and a sample of MCI control participants. The measure of capacity is shown to offer increased classificatory sensitivity relative to the standard behavioral measures, and is also shown to be the behavioral measure that correlated most strongly with hippocampal volume.     

A Family Affair: Examining the Impact of Parental Infidelity on Children Using a Structural Family Therapy Framework

Infidelity has a permeating impact on social systems, but no system is more impacted by infidelity than the nuclear family. This paper examines the impact of parental infidelity on the family using a structural family therapy (SFT) framework. Conceptualizing and treating infidelity from an SFT approach provides a systemic understanding of how interactions between the parental units about infidelity impact parent–child dynamics. Clinical recommendations are outlined for couple and family therapists to help families find healthy and adaptable ways to create and maintain structures that minimize the harmful impact of infidelity on the family system.     

Mild cognitive impairment: an overview

Mild cognitive impairment (MCI) refers to the transitional state between the cognitive changes of normal aging and very early dementia. MCI has generated a great deal of research from both clinical and research perspectives. Several population- and community-based studies have documented an accelerated rate of progression to dementia and Alzheimer's disease in individuals diagnosed with MCI. Clinical subtypes of MCI have been proposed to broaden the concept and include prodromal forms of a variety of dementias. An algorithm is presented to assist the clinician in identifying subjects and subclassifying them into the various types of MCI. Progression factors, including genetic, neuroimaging, biomarker, and clinical characteristics, are discussed. Neuropathological studies indicating an intermediate state between normal aging and early dementia in subjects with MCI are presented. The recently completed clinical trials as well as neuropsychological and nutritional interventions are discussed. Finally, the clinical utility of MCI, and directions for future research are proposed.     

Age-Related Differences in Implicit Learning of Non-Spatial Sequential Patterns

This experiment investigated whether there are age differences in implicit learning of non-spatially arranged sequential patterns. We tested 12 young and 12 old participants for five sessions each in a non-spatial alternating serial reaction time (ASRT) task, in which predictable pattern events alternated with random, unpredictable ones. People of both ages were able to learn the sequence, but older people showed less pattern sensitivity than younger ones. Neither group was able to exhibit declarative knowledge of the pattern or to discriminate between pattern and random sequences on a recognition test, suggesting that the learning was indeed implicit. These findings indicate that the age deficits previously observed in the learning of spatial sequences are not due solely to age-related deficits in visuo-spatial attention or control of eye movements, but rather reflect a more general deficit in the ability to learn subtle sequential regularities.     

Family of Origin Predictors of Marital Outcomes Among Coptic Orthodox Christian Egyptian-American Couples

Despite the importance of family within the Coptic community, the extant literature on Coptic family relationships is remarkably limited. The purpose of this study was to explore parental marital quality and family of origin (FOO) quality as predictors of marital satisfaction and marital stability among Coptic Orthodox Christian Egyptian-American couples. Self-report survey data from 255 married Coptic couples living in the United States were analyzed using an actor-partner interdependence model. Results indicated husband FOO quality predicted both marital satisfaction (β =.51, SE?=?.18, p?=?.005) and marital stability (β?=?.51, SE?=?.22, p?=?.022) among Coptic husbands but not among Coptic wives. Results further indicated wife parental marital quality, wife FOO quality, and husband parental marital quality were not predictive of marital satisfaction or marital stability among Coptic husbands or wives. Clinical implications, limitations, and recommendations for future research are discussed.