The Neural Bases of Drawing. A Meta-analysis and a Systematic Literature Review of Neurofunctional Studies in Healthy Individuals

Neuropsychology Review - Drawing is a multi-component process requiring a wide range of cognitive abilities. Several studies on patients with focal brain lesions and functional neuroimaging studies...     

BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure

Post-traumatic stress disorder (PTSD) is a syndrome resulting from exposure to a severe traumatic event that poses threatened death or injury and produces intense fear and helplessness. The neural structures implicated in PTSD development belong to the limbic system, an important region for emotional processing. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that serves as survival factor for selected populations of central nervous system (CNS) neurons and plays a role in the limbic system by regulating synaptic plasticity, memory processes and behavior. Impaired BDNF production in the brain can lead to a variety of CNS dysfunctions including symptoms associated with PTSD. However, so far fewer studies have investigated this neurotrophin in patients with PTSD. Furthermore, given the multiple role of BDNF in various CNS disorders, it cannot be excluded that traumatic events per se may influence neurotrophin levels, without a direct association to the PTSD syndrome.     

The scientific turn in metaphysics: a factualist approach

In a recent paper, Cumpa (Am Philos Q 51(4): 319–324, 2014) argues that a scientific turn in metaphysics requires the acceptance of a materialist criterion of fundamentality, according to which the most fundamental metaphysical category is the one that provides us with a reconciliation of the ordinary world and the physical universe. He concludes that the dominant category of substance cannot be the most fundamental category, for it does not satisfy this criterion of fundamentality. The most fundamental category is instead the category of fact. Although convincing, the defense of factualism over substantialism offered by Cumpa takes into account the case of classical physics without considering the physical universe of quantum mechanics. My aim in this paper is to offer a completion to Cumpa’s factualist approach. To achieve my aim, I show that substances cannot provide a satisfactory account of the relationship between the ordinary world and the physical universe even in the case of quantum mechanics, whereas a factualist approach does.

     

Drawing with oblique coordinates: on a single case

We describe a patient with right hemisphere damage affected by mild left visuo-spatial neglect and constructional apraxia. During the rehabilitation, he failed to draw a draught-board using horizontal and vertical trajectories, but he performed it successfully using oblique trajectories. These observations suggested an impairment of vertical/horizontal spatial coordinates system. In copying tasks including figure elements in different orientations he drew more accurately components in oblique orientation, whereas failed to reproduce components in horizontal orientation. The patient performed visuospatial perceptual and perceptual-imaginative tasks successfully. From these findings, it is possible to suggest that the oblique coordinate system of reference operates independently of vertical and horizontal coordinate systems in building a complex figure and that, therefore, cardinal orientation do not constitute a reference norm to define oblique orientation, as previously suggested.     

Assessing the automaticity of the exogenous orienting of tactile attention

We examined whether or not abrupt tactile onsets are capable of exogenously capturing tactile spatial attention when visual spatial attention is focused elsewhere. In experiment 1, we compared performance under dual-task conditions (where participants performed a tactile exogenous cuing task and a rapid serial visual presentation--RSVP--task at the same time) with their performance under single-task conditions (where the participants had to perform only the cuing task, although the RSVP stream was still presented in the background) and to a no-stream condition (where only the cuing task was presented). Tactile cuing was completely suppressed in both the dual-task and single-task conditions, showing that exogenous tactile spatial orienting is modulated by visual-spatial attention, which hence appears to be far from truly automatic. In experiment 2, we demonstrated that the abolishment of exogenous tactile orienting was not caused by the transient presentation of abrupt onset stimuli (letters). These results therefore show that exogenous spatial attentional orienting toward abrupt peripheral tactile stimuli is possible as long as perceptual resources are not depleted by a perceptually demanding (RSVP) task.     

Theory of mind and joint action in Parkinson’s disease

It has been suggested that the Theory of Mind (ToM) may rely on more basic processes of social cognition, such as action control (e.g., joint action), even if little is known about this relationship. The relationship between ToM and joint action can be studied in patients with Parkinson’s disease (PD), because they are characterized not only by a deficit in ToM (and in its cognitive and affective subcomponents) but also by a deficit in the inhibition of competing responses. Sixty PD patients and 60 matched healthy controls (HCs) performed a go/no-go Flanker task in both joint and individual conditions. Cognitive (Advanced Test or AT) and affective (Emotion Attribution Task or EAT) ToM also were measured. Thirty-five PD patients and matched HCs also performed the standard Flanker task, as a control measure. In patients, only individuals with high AT scores exhibited a joint Flanker effect, whereas in HCs the joint effect was found irrespectively of AT score. Patients with low EAT scores showed a greater interference effect than patients with high scores, whereas the opposite pattern was found for HCs. In regression analysis AT and EAT scores predicted the Flanker effect in the joint condition only. In the standard task, both groups showed a Flanker effect. The role of different fronto-striatal circuits, especially in PD patients, could explain the different involvement of cognitive and affective ToM in joint tasks. The Flanker effect is discussed considering the referential coding account and the attention-focus account as possible candidates to explain joint action effects.     

De-polarizing verbal irony

In three studies participants were asked to rate the degree of irony perceived in comments relating to five variations of a scenario, ranging from one pole to the opposite pole and passing through three in-between states. In study 1, the comments pertained to the polar extremes of a dimension, e.g. “It’s uphill!” stated with reference to varying degrees of steepness both uphill and downhill (i.e. steep, slightly steep, flat, slightly sloping downhill and steeply sloping downhill). In study 2, the comments were of an “intermediate” nature (e.g. “This hill is neither uphill nor downhill!”) and, as in Study 1, they were used to refer to the same five varying degrees of the same dimension. Study 3 involved the stimuli from both of the first two experiments in a between-participants design.

The results consistently demonstrated that verbal irony does not only apply to (weakly or strongly) polarised statements and situations, but it can also apply to intermediate comments and experiences. The perceptual structure of the dimensions involved modulates the effect.     

New perspectives in assessing deception: The evolution of the truth machine

In recent years a growing interest has arisen in the development of tools for the detection of deception. Since William M. Marston's first publication (1917) on the use of the polygraph as a lie detector, the application of this tool, commonly known as the truth machine, has evolved. Modern technologies are now trying to push the issue further, investigating brain activity during deception using functional Magnetic Resonance Imaging (fMRI). The aim of this paper is to summarise the evolution of research from the original use of the polygraph to the use of new technologies in detecting deception, in order to provide an overview of the recent developments on the use of measurements of deception, and promote new research in this highly important domain of applied cognitive psychology.     

The suppression of reflexive visual and auditory orienting when attention is otherwise engaged

Two experiments were conducted to examine whether abrupt onsets are capable of reflexively capturing attention when they occur outside the current focus of spatial attention, as would be expected if exogenous orienting operates in a truly automatic fashion. The authors established a highly focused attentional state by means of the central presentation of a stream of visual or auditory characters, which participants sometimes had to monitor. No intramodal reflexive cuing effects were observed in either audition or vision when participants performed either an exogenous visual or auditory orthogonal cuing task together with the central focused attention task. These results suggest that reflexive unimodal orienting is not truly automatic. The fact that cuing effects were eliminated under both unimodal and cross-modal conditions is consistent with the view that auditory and visual reflexive spatial orienting are controlled by a common underlying neural substrate.