大鼠作业成绩与脑内亮氨酸脑啡肽含量变化的相关性研究

本工作采用穿梭式电击回避反应法和脑啡肽的放射免疫测定法,分析比较了大鼠作业成绩与脑内壳氨酸脑啡肽(Leu-enkephalin,LEK)含量的关系,在本实验条件下,观察到作业成绩不良组纹状体内LEK含量显著高于成绩优良组和对照组,并由实验证明,它们之间的差异不是由于在实验中接受电击的次数或电击总量不同造成的。这一结果提示,内源性亮氨酸脑啡肽可能参与记忆获得的调制。     

不同学习方式下习得性长时程突触增强形成的特点

一般认为,突触传递的长时程增强(Long-term potentiation,LTP)可能是学习和记忆的神经基础。我室的系列工作表明,大鼠在条件性行为的建立中,海马齿状回、CA_3、CA_1区均出现LTP样变化,并将之称为习得性LTP(Learning-de-pendent LTP),而且发现每次训练作业后突触效应的增强,经一段时间(4小时)后就     

乳头体和隔区在大鼠条件性味觉痕迹的形成和保存中的作用

本工作是在前一工作的基础上,进一步研究分别电损毁有关回路的乳头体、隔区,对以糖精水为条件刺激。氯化锂腹腔注射引起中毒作为非条件刺激的条件性糖精厌恶痕迹的形成和保存的影响。结果表明,无论是损毁乳头体,或者隔区,对条件性糖精厌恶痕迹的形成和保存均无影响。说明在本实验条件下,这种条件性味觉痕迹的形成与保存,不依赖边缘系统的乳头体、海马、隔区这些回路的参与,这就进一步说明味觉信号的记忆确有其不同于视、听觉信号的记忆的机制的。     

Predication and Hume's Conceivability Principle

In this paper, I will make the case that an associative account of predication in Hume seems to allow for impossible predicative conceptions—that is, the conceiving of impossible states of affairs involving subjects instantiating properties or qualities—which violate his Conceivability Principle. The natural response is to argue that such conceptions are not clear and distinct, but substantive worries are raised about a number of attempted solutions along these lines. This poses a predicament for Hume scholars: either we must modify or abandon the Conceivability Principle, or reject an associative account of predication, or concede that Hume faces a difficulty he cannot solve.     

海马CA_3区习得性LTP的进一步探讨

分辨学习中大鼠ＰＰ－ＣＡ_３突触效应有习得性ＬＴＰ产生,进一步观察到ＭＦ－ＣＡ_３及Ｃｏｍｍ－ＣＡ_３也同步地产生习得性ＬＴＰ,表明几种输入突触都产生习得性ＬＴＰ,而ＭＦ－ＣＡ_３突触效应增强的程度则较Ｃｏｍｍ－ＣＡ_３的为大（Ｐ＜０．０１）。海马ＣＡ_３注入印防己毒素能易化ＰＰ－ＣＡ_３突触习得性ＬＴＰ的产生,工作发现一侧海马ＣＡ_３注印防己毒素,易化对侧ＭＦ－ＣＡ_３突触习得性ＬＴＰ的产生,表明两侧海马ＣＡ_３区在其习得性ＬＴＰ的形成上是相互协同的。     

乳头体对海马齿状回习得性长时程突触增强的影响

用高频电脉冲刺激大鼠乳头体（ＭＢ）,可一过性抑制由刺激穿通纤维（ＰＰ）诱发的海马齿状回（ＤＧ）群体锋电位（ＰＳ）。训练作业前先刺激ＭＢ,导致ＤＧ的习得性长时程突触增强（ＬＤＬＴＰ）的形成显著延缓,相应地延缓了条件性饮水反应的建立。电刺激ＭＢ对ＰＰ─ＤＧＰＳ的这种抑制作用在训练所产生的ＰＳ增大达最高水平时显著减弱,刺激ＭＢ对ＬＤＬＴＰ的保持及相应地对条件反应的巩固没有明显影响。结果表明ＭＢ对ＤＧＬＤＬＴＰ的形成有抑制性调制作用。     

Word Order Variation is Partially Constrained by Syntactic Complexity

Previous work suggests that when speakers linearize syntactic structures, they place longer and more complex dependents further away from the head word to which they belong than shorter and simpler dependents, and that they do so with increasing rigidity the longer expressions get, for example, longer objects tend to be placed further away from their verb, and with less variation. Current theories of sentence processing furthermore make competing predictions on whether longer expressions are preferentially placed as early or as late as possible. Here we test these predictions using hierarchical distributional regression models that allow estimates of word order and word order variation at the level of individual dependencies in corpora from 71 languages, while controlling for confounding effects from the type of dependency (e.g., subject vs. object), and the type of clause (main vs. subordinate) involved as well as from trends that are characteristic of individual languages, language families, and language contact areas. Our results show the expected correlations of length with position and variation only for two out of six dependency types (obliques and nominal modifiers) and no difference between clause types. These findings challenge received theories of across-the-board effects of complexity on word order and word order variation and call for theoretical models that relativize effects to specific kinds of syntactic structures and dependencies.     

Visual attention shift to printed words during spoken word recognition in Chinese: The role of phonological information

The aim of this study was to investigate the extent to which phonological information mediates the visual attention shift to printed Chinese words in spoken word recognition by using an eye-movement technique with a printed-word paradigm. In this paradigm, participants are visually presented with four printed words on a computer screen, which include a target word, a phonological competitor, and two distractors. Participants are then required to select the target word using a computer mouse, and the eye movements are recorded. In Experiment 1, phonological information was manipulated at the full-phonological overlap; in Experiment 2, phonological information at the partial-phonological overlap was manipulated; and in Experiment 3, the phonological competitors were manipulated to share either fulloverlap or partial-overlap with targets directly. Results of the three experiments showed that the phonological competitor effects were observed at both the full-phonological overlap and partial-phonological overlap conditions. That is, phonological competitors attracted more fixations than distractors, which suggested that phonological information mediates the visual attention shift during spoken word recognition. More importantly, we found that the mediating role of phonological information varies as a function of the phonological similarity between target words and phonological competitors.     

流动儿童疏离感的特点及其与应对方式、学校态度的关系

采取整群抽样的方法,对成都及重庆两地591名流动儿童和272名城市儿童进行问卷调查,考察流动儿童疏离感的特点及其与应对方式和学校态度的关系。结果发现:(1)流动儿童疏离感各维度显著高于城市儿童;流动初中生的疏离感显著高于流动小学生,且男生的疏离感显著高于女生;(2)流动儿童疏离感的三个维度之间存在显著差异,其中社会疏离感最高,其次是环境疏离感,人际疏离感最低;(3)流动儿童疏离感对学校喜欢有显著的负向影响,而对学校回避有显著的正向影响;应对方式在流动儿童疏离感对学校态度的影响中起着部分中介作用。     

Electrodeposition,assisted by abrasive polishing,of crack-free hard chromium with compressive stress

Crack networks and residual tensile stresses are general characteristics of electrodeposited hard chromium coatings. In this paper, crack-free hard chromium coatings with compressive stresses have been obtained by an electrodeposition process assisted by abrasive polishing. The deposited coatings had mirror-like smooth surfaces, values of hardness in the range 800–1000 HV and compressive stresses between 1000 and 1600 MPa. A model involving hydrogen disentanglement from the lattice is proposed to explain the effects of abrasive polishing on the complete elimination of cracks and the generation of a compressive stress. This explanation is discussed in terms of the variations in properties of the coating with the rotation speed of the cathode.