Bacterial Melanin Improves Cognitive Impairment Induced by Cerebral Hypoperfusion in Rats

The effect of bacterial melanin (BM) solution on learning and memory impairment induced by chronic cerebral hypoperfusion in rats was studied. Male rats were injected intramuscularly with BM solution on the second day after bilateral permanent occlusion of the common carotid artery. Rats received 6 mg/ml (170 mg/kg) BM and performed significantly better in cognition tests compared with controls. The present findings demonstrate that the beneficial effects of BM injection on cognitive functions may be due to preventing neuropathological alterations, suppressing the inflammation process, stimulating vascularization and inhibiting oxidative damage. Obtained data suggest that BM has therapeutic potential for the treatment of neurodegeneration caused by ischemia.     

A detection-theoretic model of echo inhibition

A detection-theoretic analysis of the auditory localization of dual-impulse stimuli is described, and a model for the processing of spatial cues in the echo pulse is developed. Although for over 50 years "echo suppression" has been the topic of intense theoretical and empirical study within the hearing sciences, only a rudimentary understanding of its mechanisms has emerged. In this article, psychometric functions and results from matching studies are used in developing a model that specifies the perceived position of the echo pulse as a normal deviate, with an expectation that is a logistic function of the echo delay and a variance that depends on interaural time difference. Loss of information in the echo event is quantified as a decline in the efficiency with which the binaural system receives information from the lag impulse.     

Psychometric and Logometric Properties of the Armenian Version of Augmentative and Alternative Communication Assessment Questionnaire: Assessing Reliability and Validity

Journal of Psycholinguistic Research - The study describes the development of the AAC-Arm questionnaire and its initial psychometric and logometric testing for reliability and validity....