Effects of chronic variable stress and antidepressant drugs on behavioral inactivity during an uncontrollable stress: interaction between both treatments.

Rats submitted to a chronic variable stress regime exhibited more inactivity during inescapable shock as compared with unstressed rats. Besides, chronic treatments with desipramine, imipramine, clomipramine, or phenelzine reduce the amount of inactivity exhibited during this aversive experience. Furthermore, the combination of both chronic treatments--stress and antidepressants--resulted in a potentiation of the antidepressant effect alone. This higher antidepressant efficacy may result from the interaction of the neural mechanisms triggered by chronic stress exposure and antidepressant drugs.     

Motion aftereffects with rotating ellipses

Summary The perceptual outcome and the motion-aftereffect duration generated by the rotation on the frontal plane of an ellipse with a bar depend on whether the bar is placed along the major or the minor axis. When the bar is placed along the minor axis, a stereokinetic transformation occurs, and the pattern looks like a tilting ring with a perpendicular bar moving rigidly with it. Placing the bar along the major axis prevents the stereokinetic transformation: subjects report deformations and relative motion of the bar with respect to the ellipse. We found that motion aftereffects last longer when the bar is placed along the minor rather than along the major axis. A series of experiments was carried out to investigate whether differences in aftereffect duration are related to the stereokinetic transformation. Results seem to suggest that they are not.The authors' names are in alphabetical order.     

Differential ethanol olfactory experiences affect ethanol ingestion in preweanlings but not in older rats

Preweanling (21 days old) and adult (60-80 days old) rats were exposed to ethanol odor either paired with the early stages of apomorphine-induced toxicosis, paired with the recovery from toxicosis, or unpaired with the induction of distress. Twenty four hours later, ethanol preferences were measured in a spatial olfactory test (ethanol vs lemon odor) or a drinking test (5.6% v/v ethanol vs 0.25% w/v citric acid solutions). During the olfactory test both young and adult rats expressed substantial ethanol odor aversions when previously exposed to this odor paired with toxicosis. However, changes in ethanol intake became apparent only in preweanling subjects. Preweanlings which received the ethanol odor paired with illness drank significantly less of the ethanol solution relative to controls, while subjects experiencing the odor paired with recovery from distress significantly increased their consumption of the ethanol solution. These prior aversive and appetitive olfactory experiences had no effect upon ethanol intake in adult rats. These results implicate both an ontogenetic and a sensorial factor in the regulation of ethanol intake.     

Weanlings' transfer of conditioned ethanol aversion from olfaction to ingestion depends on the unconditioned stimulus

Weanling (21-day-old) rats were exposed to an alcohol odor paired with either an interoceptive (apomorphine-induced illness) or exteroceptive (footshock-induced distress) reinforcer. Twenty-four hours later, ethanol preferences were measured in a locational olfactory test (ethanol vs lemon odor) or an ingestion test (5.6% v/v ethanol vs 0.25% v/v citric acid solution). Weanling rats expressed substantial olfactory aversions, independent of the reinforcer employed in conditioning. During the drinking test, however, only rats that had experienced the ethanol odor paired with internal malaise showed a significant reduction in the intake of the ethanol solution when compared to unpaired controls. Furthermore, rats that had experienced the ethanol odor paired with external distress drank significantly more of the ethanol solution than their controls. These results provide further evidence that olfactory experiences with ethanol can lead to changes in ethanol ingestion, and indicate that the nature of the unconditioned stimulus is critical in establishing the ingestive effect.     

“You're overreacting!”: The ambiguity of Asian American microaggressions delegitimizes collective action

Asian Americans are lauded as the model minority who are intelligent and industrious. Simultaneously, they are deemed as perpetual foreigners. The current research examines how racial microaggressions expressed by a White American source toward an Asian American target affect perceptions of the perpetrator and target. White Americans and Asian Americans read about an interaction between two college students, where the racial microaggression made was either an ambiguous expression of the model minority myth (MMM; all studies), an ambiguous perpetual foreigner stereotype (all studies), an unambiguous MMM (all studies), or no racial bias (Studies 2 and 3). Findings indicate that both Whites and Asian Americans respond differently—when exposed to the aforementioned conditions—regarding perceived racism of the White perpetrator and appropriateness of response by the Asian American target; however, they respond similarly regarding perceived legitimacy of collective action by the target. Nevertheless, Whites and Asian Americans deemed the ambiguous microaggression against the target as a model minority not racist relative to unambiguous MMM. Our findings show that ambiguous forms of bias toward Asian Americans go “under the radar” of both Whites and Asian Americans as being racist and contribute to the maintenance of the racial status quo.     

Revisitation of the luminance conditions for the occurrence of the achromatic neon color spreading illusion

This paper develops the idea (Bressan, 1993) that neon spreading derives from the perceptual scissioning of ordinary assimilation color, a process identical to that occurring with nonillusory colors in phenomenal transparency. It is commonly held that the critical elements in achromatic neon spreading patterns must be of luminance intermediate between that of the embedding lines and of the background. The interpretation of neon spreading on the basis of color scissioning, however, predicts that neon spreading should also be observed for different luminance hierarchies, provided that these are compatible with transparency. This prediction found experimental support in the present work. The results suggest that (1) the widespread notion that chromatic and achromatic neon spreading must be mediated by separate mechanisms is unwarranted; (2) the widespread notion that color spreading in ordinary assimilation patterns and color spreading in neon patterns must be mediated by separate mechanisms is unwarranted; and (3) other than pointing to the way in which the overall organization of a scene affects the mode of color appearance, the neon spreading effect may not convey any extra theoretical relevance.     

Ethanol-mediated taste aversions and state-dependency in preweanling (16-day-old) rats

Requirements for conditioning of an ethanol-mediated taste aversion in 16-day-old rat pups were examined. Experiment 1 demonstrated that preweanling rats are capable of acquiring, in two trials, an aversion to a 15% sucrose solution when followed by intragastric intubation of a 1.2 g/kg dose of 17% v/v ethanol, but not when followed by a 0.4 g/kg dose. Comparison was with control animals given sucrose followed by an equivalent volume isocaloric Half and Half. When the 0.4 g/kg dose of ethanol preceded sucrose presentation by 30 min (Experiment 2), the aversion was learned, suggesting that the effective delay between the sucrose and the critical consequences of the ethanol had been too long with the former procedure. Expression of the sucrose aversion required, however, the reinstatement of the context of intoxication--state-dependent retention. Finally, the results of Experiment 3B indicated that, in addition to the association between the sucrose and the aversive consequences of alcohol intoxication, the orosensory cues resulting from alcohol's direct elimination, via such processes as respiration and salivation, became associated with the appetitive properties of the sucrose. This was evidenced by a conditioned increase in preference for ethanol odor. Possible age-related differences in the ability to associate stimuli with alcohol's unconditioned consequences, and in state dependency are discussed.     

In Vitro Fertilization: A Pastoral Taboo?

Journal of Religion and Health - Scholars have shown how the moral limitations and caveats that many religions pose against new assisted reproductive technologies have hindered women’s...