How the mind hurts and heals the body

The author reviews some of the social and behavioral factors acting on the brain that influence health, illness, and death. Supported with data from several areas of research, his proposal for understanding health and illness provides both the concepts and the mechanisms for studying and explaining mind-body relationships. The brain is the body's first line of defense against illness, and the mind is the emergent functioning of the brain. This mind-body approach incorporates ideas, belief systems, and hopes as well as biochemistry, physiology, and anatomy. Changing thoughts imply a changing brain and thus a changing biology and body. Belief systems provide a baseline for the functioning brain upon which other variables act and have their effects.     

Creation and Implementation of an Environmental Scan to Assess Cancer Genetics Services at Three Oncology Care Settings

An environmental scan (ES) is an efficient mixed-methods approach to collect and interpret relevant data for strategic planning and project design. To date, the ES has not been used nor evaluated in the clinical cancer genetics setting. We created and implemented an ES to inform the design of a quality improvement (QI) project to increase the rates of adherence to national guidelines for cancer genetic counseling and genetic testing at three unique oncology care settings (OCS). The ES collected qualitative and quantitative data from reviews of internal processes, past QI efforts, the literature, and each OCS. The ES used a data collection form and semi-structured interviews to aid in data collection. The ES was completed within 6 months, and sufficient data were captured to identify opportunities and threats to the QI project’s success, as well as potential barriers to, and facilitators of guideline-based cancer genetics services at each OCS. Previously unreported barriers were identified, including inefficient genetic counseling appointment scheduling processes and the inability to track referrals, genetics appointments, and genetic test results within electronic medical record systems. The ES was a valuable process for QI project planning at three OCS and may be used to evaluate genetics services in other settings.     

The timing of brain events: authors' response to Libet's 'reply'

A commentary in response to B. Libet: 'The timing of brain events: Reply to the "Special Section" in this journal of September 2004, edited by Susan Pockett' ().     

On-line Homework/Quiz/Exam applet: Freely available Java software for evaluating performance on line

The Homework/Quiz/Exam applet is a freely available Java program that can be used to evaluate student performance on line for any content authored by a teacher. It has database connectivity so that student scores are automatically recorded. It allows several different types of questions. Each question can be linked to images and detailed story problems. Three levels of feedback are provided to student responses. It allows teachers to randomize the sequence of questions and to randomize which of several options is the correct answer in multiple-choice questions. The creation and editing of questions involves menu selections, buttonpresses, and the typing of content; no programming knowledge is required. The code is open source in order to encourage modifications that will meet individual pedagogical needs.     

异体造血干细胞移植问题、发展与思考

异体造血干细胞移植(Allo-HSCT)已成为治疗恶性血液病及其他各种疾病的有效方法之一。在Allo-HSCT中由于供体和受体免疫屏障的存在。从而一开始就是一个供受体矛盾的对立统一的过程。对其中矛盾的研究和解决充满了辩证唯物的哲学思想。也促使Allo-HSCT技术不断发展。新的方法和理念不断出现。使Allo-HSCT治疗白血病的疗效不断提高。     

Backward conditioning in the rabbit (Oryctolagus cuniculus).

Backward conditioning of the nictitating membrane response of rabbits was studied. The prior exposure to unconditional stimulus-conditional stimulus (US-CS) pairings retarded subsequent forward conditioning. Control procedures eliminated latent inhibition and forward safety-signal effects as accounting for the data. The relevance of this report to other recent studies of backward conditioning is discussed.     

The reductio argument against epistemic infinitism

Synthese - Epistemic infinitism, advanced in different forms by Peter Klein, Scott Aikin, and David Atkinson and Jeanne Peijnenburg, is the theory that justification of a proposition for a person...     

How to Release Oneself from an Obligation: Good News for Duties to Oneself

In some cases, you may release someone from some obligation they have to you. For instance, you may release them from a promise they made to you, or an obligation to repay money they have borrowed from you. But most take it as clear that, if you have an obligation to someone else, you cannot in any way release yourself from that obligation. I shall argue the contrary. The issue is important because one standard problem for the idea of having duties to oneself relies on the impossibility of self-release. The argument (the ‘Release Argument’) is that a duty to oneself would be a duty from which one could release oneself, but that this is an absurdity, and so there can be no duties to oneself. This argument is to be rejected because a duty from which one can release oneself is perfectly possible, and such release occurs quite properly from time to time.