A meta-analytic review of stopping performance in attention-deficit/hyperactivity disorder: deficient inhibitory motor control?

This review discusses whether deficient inhibitory motor control is the core deficit of attention-deficit/hyperactivity disorder (ADHD). Inhibitory motor control is commonly assessed using the stop-signal paradigm. Since the last meta-analysis that was performed, 33 new studies have appeared. The current meta-analysis revealed a significant difference between ADHD patients and matched controls in stop latency (stop-signal reaction time) in both children and adults. Basic reaction time was significantly longer in children with ADHD, but not in adults, and there was a significant interaction between the elongation of the latency to stop and to respond in adults, but not in children. Deficient inhibitory motor control may be less crucial in children than in adults with ADHD.     

HIV-related stigma in African and Afro-Caribbean communities in the Netherlands: manifestations, consequences and coping

HIV-related stigma in African and Afro-Caribbean diaspora communities in the Netherlands was investigated. Interviews with HIV-positive and HIV-negative community members demonstrated that HIV-related stigma manifests as social distance, physical distance, words and silence. The psychological consequences of HIV-related stigma among those diagnosed with HIV reported were emotional pain, sadness, loneliness, anger, frustration and internalised stigma. The social consequences included decreased social network size, limited social support and social isolation, and resulted from not only enacted stigma but also self-imposed social withdrawal. Also, poor treatment adherence was a health-related consequence. People living with HIV employed both problem-focused and emotion-focused coping strategies to mitigate the negative consequences of stigma. Problem-focused coping strategies included selective disclosure, disengagement, affiliating with similar others, seeking social support and, to a lesser extent, activism. Emotion-focused strategies included distraction, positive reappraisal, religious coping, external attributions, disidentification and acceptance. HIV-related stigma clearly permeates African and Afro-Caribbean communities in the Netherlands, and should be targeted for intervention.     

Reducing the risk of bias in health behaviour change trials: Improving trial design,reporting or bias assessment criteria? A review and case study

Objective: It has been suggested that randomised controlled trials (RCTs) of health behaviour change (HBC) interventions are less rigorously designed than – for example– drug trials. This study presents an approach to clarifying whether this is due to poor trial design, incomplete trial reporting and/or the inappropriateness of commonly applied risk of bias assessment criteria.

Design: First, a framework of key sources of bias and common strategies for reducing bias risk is developed based on a literature review. Second, we describe the design of a multi-site RCT evaluating the cost-effectiveness of an HIV-treatment adherence intervention (case study). The choices made by the multidisciplinary team trying to minimise the risk of bias are compared against the risk of bias framework.

Main outcome measures: Implementation of common strategies for reducing the risk of bias in the case study; alternative or additional strategies applied; a justification for each deviation from the risk of bias framework.

Results: Most of the common strategies for reducing the risk of bias could be implemented. Alternative strategies were developed for minimising the risk of performance bias and contamination. Several additional, domain-specific risk of bias strategies were implemented.

Conclusions: The literature provides useful guidance for reducing the risk of bias in HBC trials. Yet, the case study suggests that HBC trial designers may face specific challenges that require alternative/additional measures for reducing the risk of bias. Using the risk of bias justification table (RATIONALE) could lead to better-designed HBC trials, more comprehensive trial reports and the data necessary for evaluating the appropriateness of commonly applied risk of bias assessment criteria to HBC trials.     

How highlighted utensils influence consumption in a dark setting

Abstract

Objective: Previous research has shown that people consume less food in the dark compared to normal vision conditions. While this effect is commonly attributed to increased attention to internal cues, it could also be caused by increased difficulty to maneuver in a dark setting. This study investigated this potential alternative explanation.

Design: A 2 (dark versus normal vision setting)?×?2 (highlighted versus non-highlighted utensils) between-subjects design was employed.

Main outcome measures: Perceived difficulty of maneuvering and consumption of yoghurt were assessed as main outcome measures.

Results: Participants consumed marginally less in dark compared to normal vision conditions, and experienced higher difficulty of maneuvering. Importantly, both effects were qualified by a significant interaction with highlighting, which increased consumption and reduced perceived difficulty compared to no highlights. Difficulty of maneuvering did not mediate the interactive effect of vision and highlighting on consumption.

Conclusion: Difficulty to maneuver should be considered when investigating eating behaviour under dark conditions. In line with an embodied cognition account, results also reveal the necessity of visual information for interaction with objects in the environment and imply that detail-deprived object information may be sufficient for activation of the motor system.     

Reference frame preferences in haptics differ for the blind and sighted in the horizontal but not in the vertical plane

We investigated which reference frames are preferred when matching spatial language to the haptic domain. Sighted, low-vision, and blind participants were tested on a haptic-sentence-verification task where participants had to haptically explore different configurations of a ball and a shoe and judge the relation between them. Results from the spatial relation "above", in the vertical plane, showed that various reference frames are available after haptic inspection of a configuration. Moreover, the pattern of results was similar for all three groups and resembled patterns found for the sighted on visual sentence-verification tasks. In contrast, when judging the spatial relation "in front", in the horizontal plane, the blind showed a markedly different response pattern. The sighted and low-vision participants did not show a clear preference for either the absolute/relative or the intrinsic reference frame when these frames were dissociated. The blind, on the other hand, showed a clear preference for the intrinsic reference frame. In the absence of a dominant cue, such as gravity in the vertical plane, the blind might emphasise the functional relationship between the objects owing to enhanced experience with haptic exploration of objects.     

Verbal fluency over time as a measure of automatic and controlled processing in children with ADHD

The performance of ADHD children on semantic category fluency (SCF) versus initial letter fluency (ILF) tasks was examined. For each participant, word production was recorded for each 15-s time slice on each task. Performance on both fluency tasks was compared to test the hypothesis that children with ADHD are characterized by a performance deficit on the ILF task because performance on this task is less automated than performance on the SCF. Children classified with ADHD (N = 20) were compared to children with other psychopathology (N = 118) and healthy controls (N = 130). Results indicated that the groups could not be differentiated by the total number of words produced in 60 s in either fluency task. As hypothesized, a significant interaction of group by productivity over time by type of fluency task was found: ADHD children had more problems finding words in the first 15 s of the IFL than did children in the other two groups, and as compared with their performance on the SCF. Results were taken to indicate that children with ADHD symptoms show a delay in the development of automating skills for processing abstract verbal information.     

Neurocognitive performance of 5- and 6-year-old children who met criteria for attention deficit/hyperactivity disorder at 18 months follow-up: results from a prospective population study

The aim of this prospective study was to examine whether neurocognitive performance of children aged 5–6 years distinguished children who were later diagnosed with attention deficit/hyperactivity disorder (ADHD) or borderline ADHD from children without ADHD after adjustment for behavioral measures and to examine the influence of comorbid psychopathology. Out of a general population of 1,317 children, 366 children were selected on the basis of their scores on the Child Behavior Checklist (CBCL). Eighteen months later, the parents were interviewed using a standardized child psychiatric interview: 33 children were classified as ADHD and 75 children as borderline ADHD, and there were 258 children without ADHD. Children with rated ADHD were significantly impaired on measures of visuomotor ability and working memory compared to children without ADHD after adjustment for CBCL results. The performance of borderline ADHD children was in between that of children with and without ADHD. In addition, 4 groups of children were analyzed: 9 ADHD, 24 ADHD with comorbid oppositional defiant disorder/conduct disorder (ODD/CD), 59 ODD/CD, and 274 controls. Children with rated comorbid ADHD and ODD/CD performed significantly worse on these tasks compared to children with rated ODD/CD and control children while they did not differ from ADHD children. Our results imply that neurocognitive measures can contribute to the early identification of ADHD with and without comorbid ODD/CD.     

The Child Behavior Checklist for Group Care Workers: A Study Regarding the Factor Structure

In this study we examined the factor structure of the Child Behavior Checklist (CBCL) filled out by group care workers. Group care workers' judgements were collected on 846 children and adolescents treated in various residential settings in The Netherlands. Using confirmatory factor analysis, we were able to show that the original CBCL factor model based on parental judgments of child behavior also fits for the judgments of group care workers. This means that the well known 8 narrow-band syndromes (Withdrawn, Somatic Complaints, etc.) as well as the 2 broad-band syndromes (Internalizing and Externalizing) can be used to interpret the CBCL scores of group care workers. This confirmation of the CBCL factor structure is a first step to add a group care worker version to the CBCL family. However, as a second step, normative data need to be gathered to further enhance the use of the CBCL for group care workers.     

A Semantics for Means-end Relations

There has been considerable work on practical reasoning in artificial intelligence and also in philosophy. Typically, such reasoning includes premises regarding means–end relations. A clear semantics for such relations is needed in order to evaluate proposed syllogisms. In this paper, we provide a formal semantics for means–end relations, in particular for necessary and sufficient means–end relations. Our semantics includes a non-monotonic conditional operator, so that related practical reasoning is naturally defeasible. This work is primarily an exercise in conceptual analysis, aimed at clarifying and eventually evaluating existing theories of practical reasoning (pending a similar analysis regarding desires, intentions and other relevant concepts). “They were in conversation without speaking. They didn’t need to speak. They just changed reality so that they had spoken.” Terry Pratchett, Reaper Man     

The power of regression to the mean: A social norm study revisited

This research follows up on a study by Schultz et al. ( 2007 ), in which the effect of a social norm intervention on energy consumption was examined. The present studies included control groups to examine whether social norm effects would persist beyond regression to the mean. Both studies had a 2 (baseline consumption: below mean versus above mean) × 2 (message condition: no‐message control versus norm message) design . Based on baseline fruit ( Study 1 ) or unhealthy snack ( Study 2 ) consumption, students were classified as above mean or below mean for consumption. One week later, half of the students in the above‐mean and below‐mean groups received normative feedback; control groups did not. Neither study showed an effect of norm messages on behavior relative to control, providing evidence for regression to the mean as an alternative explanation. Findings highlight the importance of control groups to distinguish social norm intervention effects from mere regression to the mean.