Brain weights correlate with behavioral parameters in individual inbred mice housed in a common and enriched environment

Fifty 8-week-old Balb/c mice were individually identified and housed together in a large and enriched environment for 5 months. Maze and open field exploration, response to an aversive noise, swimming, and induced grooming tests were applied to each mouse in an initial search for possible relationships between brain morphology and spontaneous behavior in isogenic individuals living in a complex social and physical environment. The tasks generated 39 quantitative behavioral indices which include locomotion, rearing, still, and grooming bout frequencies, latencies, total, and mean bout durations. At the end of the tests, the 7-month-old mice were sacrificed and the fresh weights of their whole brain, cerebellum, brain stem, diencephalon, telencephalon, and prosencephalon were rapidly obtained. Behavioral data have wide variations and do not adjust to normal population distributions. Means of the same parameter differ between tests. A Spearman correlation matrix of all data yielded many significant correlations between indices of the same task which can be interpreted in terms of time budget and sequence probability. Significant correlations between indices of different tests suggest diverse emotionalities, exploratory strategies, and motor skills. The correlations between body and brain weights and among separate brain regions were not significant. There were several low but significant correlations between brain weights and behavioral indices. Such correlations, the resulting factors, and significant behavioral differences between mice with large and small brains suggest that mice displaying low motor activity in novel environments have larger brains and forebrain/hindbrain ratios than mice with high activity, and that animals with high scores of some specific behaviors have larger brain areas physiologically related to such behaviors.(ABSTRACT TRUNCATED AT 250 WORDS)     

Insincerity and disloyalty

Insincerity is the intentional conflict between a state of mind and a synchronic linguistic act. Three cases have to be distinguished: lying, as the opposition of belief and assertion (the act is untruthful); dishonesty, as the opposition of will and declaration of will (act empty); and simulation, as the opposition of emotion and exclamation (act ungenuine). One of the problems arising is: Are there insincere commands, and if not, why?

Disloyalty, on the other hand, is a diachronic inconsequence, the breach of a linguistic action (act unredeemed) which was binding for the future (such as, e.g. a promise). There is a cross-connection to dishonesty, which can be seen as the will to be disloyal.

     

The psychological cost of waiting

The study of any problem involving waiting situations invariably assumes that people dislike having to wait. The analysis of queueing problems usually prescribes that some costs should be associated with the time people spend waiting to be served. These are usually considered to be of an economic nature, though the existence of other costs of a psychological nature is accepted. It is generally accepted that after having to wait for a certain amount of time, anxiety and stress start to build up in an individual, due both to the sense of waste and the uncertainty involved in a waiting situation. This work provides a theoretical basis for analysing this building up process as it occurs during the waiting period. It is proved that, under very general conditions, the resulting psychological stress accumulated during the process is a marginal increasing function of the waiting time, and some strategies to minimise it are developed. The results obtained give theoretical support to the usual assumptions underlying the development of systems to provide “real time” information to people in waiting situations. This is especially important in the operation of public transportation systems. The results also provide theoretical support to the “convex” treatment usually given to the waiting cost function in queueing problems.     

Social structure features in three inbred strains of mice, C57Bl/6J, Balb/cj, and NIH: a comparative study

Some features of social living were investigated in three inbred strains of mice: C57Bl/6j, Balb/cj, and NIH. Five social behaviors--Aggression, Submission, Allogrooming, Social Rest and Rest Alone, as well as Wheel Running Activity--were recorded 2 h daily for a week, in 26 groups of seven male mice living in an enriched environment. Dominants and subordinates among strains shared some behavioral characteristics, but strain contributions upon social structure were also detected. Similarities among strains included the appearance of a single dominant mouse per group rated as the most aggressive, besides from being the animal presented with most Submissions. Allogrooming was more frequent among subordinates than among dominants and subordinates. Differences among strains were that agonistic behavior among subordinates was higher in the Balb/cj and NIH groups than in the C57Bl/6j mice. NIH mice were recorded in Rest Alone more often than mice from the other strains. C57Bl/6j dominants showed higher rates of Wheel Running Activity than subordinates.     

Three-dimensional perspective drawing of two-dimensional functions with microcomputers

In this paper, we present a BASIC program for Apple II series computers that allows the user to obtain perspective drawings of two-dimensional functions of known analytical expression. Also, we outline a procedure for obtaining perspective representations of two-dimensional arrays of data using the same program. The program should run on any computer with graphics mode with only slight modifications in the graphics commands.     

Existence and the existential quantifier

This paper draws a distinction between the existential quantifier and the symbol ‘∃’ used to express it, on the one hand, and existence and ‘exists’, on the other. It argues that some popular arguments in metaphysics, including arguments against vague existence and arguments against deflationary metaontology (which views ontological disputes as lacking substance), are guilty of fudging this distinction. The paper draws some lessons for metaphysical debate about existence and highlights some heretofore ignored and attractive positions in logical space.     

Finding voice in a year of collective trauma: Case study of an online photovoice project with youth

In this article, we share findings from a qualitative case study of a virtual youth photovoice program implemented across three regions of the United States. The purpose of the program was to engage youth in research on a social issue relevant to them during an unprecedented year marked by two public health crises, COVID-19 and anti-Black racial violence. Results of an analysis of curriculum and archival program materials lend support for online strategies for youth engagement including individualized support and online audiovisual presentations with avatars. Racial justice and trauma-informed adaptations were designed to be responsive to youth needs for flexible programming and safe spaces. Themes captured in the first online gallery of youth photos include (1) tools for mental health, (2) meaningful connection, and (3) community advocacy, bringing attention to structural issues as well as family and community strengths. Findings suggest photovoice can be thoughtfully adapted for youth researchers and support individual and group storytelling in response to collective trauma.     

A review on equivalence-based procedures to teach food-portion estimation skills

This review involved a systematic analysis of equivalence-based instruction (EBI) that aimed to improve food-size interventions in diverse populations. Systematic searches identified seven studies published since 2010 that met inclusion criteria. These studies were analyzed according to their participants, design, setting, content taught, training structures, training protocol, testing format, treatment integrity, and outcomes. Results showed EBI procedures for teaching food estimation skills have been mostly implemented with adults. The type of content taught in the identified studies included carbohydrate ranges, portion size with food and non-food items, measuring cups and nutritional content of calories. Majority of included studies used one-to-many training structure and simultaneous protocols for teaching stimulus relations. Five studies completed a generalization probe and three studies reported treatment integrity data. Overall, all participants demonstrated skill acquisition of novel relations between food and portion measurement aides. Recommendations for future research and clinical applications of EBI in teaching food portion estimation are presented.