惊反射在创伤后应激障碍研究中的应用:高唤醒与恐惧抑制

创伤后应激障碍(PTSD)是唯一在诊断标准中包含惊反射改变的精神疾病.相比自我报告法,对惊反射的实验室测量与总体症状关联更紧密,并已积累了较多神经机制研究成果,可作为连接前临床与临床研究的桥梁.在惊反射应用于PTSD研究的初期,它主要作为PTSD患者高唤醒症状的客观指标,但是尚未发现惊反射强度的变化与总体症状的明确关系.近年来,惊反射与情境性焦虑、恐惧抑制等新范式结合,发现特定情境下惊反射改变是PTSD患者特有的表现.惊反射在创伤应激障碍研究中所取得的新进展对PTSD病理机制的探索和临床诊断都有所启发和推进.     

行动语义、客体背景和判断任务对客体动作承载性的影响

客体动作承载性指人们知觉客体时同时激活的针对客体的行动。当Gibson最初提出动作承载性概念时, 他认为客体的这种属性是可以自动激活的。然而近年来越来越多的证据显示, 在知觉和行动的关系中, 行动语义知识和客体所处背景对客体动作承载性具有调节作用, 表现在人们可以根据这些自上而下的信息选择针对客体的适当的行动。此外, 不同的判断任务在引发客体动作承载性效应上具有特异性, 表现在若判断任务仅需知觉客体表层属性时, 不能激活对客体的动作, 进而不能产生客体动作承载性; 若判断任务需要对客体进行深层加工时, 才会激活对客体的动作。未来研究还需要进一步探究行动语义知识和客体所处背景影响客体动作承载性发生的原因和机制, 以及不同判断任务中出现结果特异性的原因。     

创伤后应激障碍中的非适应性泛化现象

过度泛化现象是区分普通心理问题和严重心理问题的重要指标。创伤后应激障碍(posttraumatic stress disorder, PTSD)患者在创伤事件后会出现非适应性的泛化。现有研究结果表明非适应性泛化(maladaptive generalization)可能是PTSD发生发展的一个重要因素, 但也有研究支持PTSD是导致了泛化从适应性向非适应性化转变的原因。虽然泛化现象的变化与PTSD症状的发展有相同趋势, 且具有共同的生理基础：记忆相关神经结构, 但二者之间的关系尚无明确定论。阐明PTSD与非适应性泛化之间的关系对PTSD的预测、诊断和治疗均有推进作用。     

两种亚型ADHD儿童的促进和抑制加工

采用图片Stroop任务,对两种亚型ADHD儿童的促进和抑制加工进行了研究。结果发现,不论在反应时还是错误率上,ADHD儿童和正常儿童在促进效应上的表现模式相似,但ADHD儿童在错误率上比正常儿童表现出更大的抑制效应,混合型ADHD儿童的抑制效应更大于注意缺陷型儿童。由于ADHD儿童仅选择性地在抑制加工上受损,而促进加工正常,这一结果提示,促进和抑制可能是具有不同机制的、分离的加工过程。     

Attentional spreading in object-based attention: The roles of target–object integration and target presentation time

What is the best account to explain the object-based attentional benefit—that is, the spread of attention within an attended object or prioritization of search across possible target locations within an attended object? Using a task in which the location of the target was known with certainty, in the present study we systematically manipulated the type (letters or bites) and the presentation time (long or short) of the target and flankers in order to test the effects of target–object integration and target presentation time on object-based attention. The results showed that an object-based effect could appear when the target was a bite, no matter whether the target presentation time was long or short; but when the target was a letter, an object-based effect was only observed when the target presentation time was short enough. These findings provide additional evidence supporting the argument of attentional spreading in object-based attention. However, this spreading is moderated jointly by target–object integration and the target presentation time.     

Why Do you Often Stop your Impulsive Behavior at the Last Moment?

Psychonomic Bulletin & Review - Intentional inhibition, a critical ability of human cognitive control, is the capacity to internally withhold a to-be-performed action. In the voluntary...     

纳络酮、地卓西平(MK-801)对大鼠食物渴求的影响

实验以条件性位置偏爱（CPP）的表达为渴求模型观察纳络酮及MK-801对大鼠食物CPP表达,探讨摄食行为调控的心理机制。48只SD大鼠分成食物组（24）与对照组（24）,3轮食物匹配训练后,在CPP表达前分别注射生理盐水、纳络酮（1.0 mg˙kg -1）及MK-801(0.1 mg˙kg -1),观察各组动物在食物匹配训练侧停留时间的变化。结果发现,MK-801促进食物CPP的表达,但纳络酮对食物CPP的表达没有显著影响。以上结果表明MK-801（0.1mg˙kg -1）增强动物的食物渴求至少是其增加摄食量的原因之一,而1.0 mg˙kg -1的纳络酮降低动物的摄食量并不是由于食物渴求的下降导致的。MK-801与纳络酮调节动物摄食行为的心理机制可能不一致。     

Action representations activated by task‐irrelevant information: Is it really irrelevant?

Accessing action knowledge is believed to rely on the activation of action representations through the retrieval of functional, manipulative, and spatial information associated with objects. However, it remains unclear whether action representations can be activated in this way when the object information is irrelevant to the current judgment. The present study investigated this question by independently manipulating the correctness of three types of action‐related information: the functional relation between the two objects, the grip applied to the objects, and the orientation of the objects. In each of three tasks in Experiment 1, participants evaluated the correctness of only one of the three information types (function, grip or orientation). Similar results were achieved with all three tasks: “correct” judgments were facilitated when the other dimensions were correct; however, “incorrect” judgments were facilitated when the other two dimensions were both correct and also when they were both incorrect. In Experiment 2, when participants attended to an action‐irrelevant feature (object color), there was no interaction between function, grip, and orientation. These results clearly indicate that action representations can be activated by retrieval of functional, manipulative, and spatial knowledge about objects, even though this is task‐irrelevant information.     

Mechanisms for the object-based negative compatibility effect: voluntary versus involuntary inhibition

This study investigates whether the object-based negative compatibility effect (NCE) originates from involuntary or voluntary inhibition. We hypothesised that both supraliminally presented primes (the prime is a mug with its handle pointing either left or right) and experimental instructions (i.e., ignoring the prime) in previous studies might induce participants to develop a voluntarily inhibitory strategy that is responsible for the object-based NCE. To test this hypothesis, we conducted 3 experiments. Experiment 1 confirmed a suitable paradigm. Experiment 2 altered participants’ strategies by varying the frequency of compatible trials across blocks. The results revealed a significant NCE for the low-frequency condition, which suggested that voluntary strategy might be primarily responsible for the object-based NCE. Experiment 3 combined a free-choice target with an object-based NCE paradigm. The results showed equivalent frequencies and mean response times between the free-choice responses that corresponded to or were opposite from the orientations of the mug handle. Combined with the results of response time quartiles, which revealed NCEs in fast responses (Q1–Q3) but no compatibility effect in slow (Q4) responses, we concluded that the object-based NCE might be primarily based on voluntary inhibition. Moreover, this inhibition might take effect earlier than that of the arrow-based NCE.