Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Do You See What I See? The Influence of Gender Stereotypes on Student and Royal Canadian Mounted Police (RCMP) Perceptions of Violent Same-Sex and Opposite-Sex Relationships

ABSTRACT

Forty-one men and 67 women undergraduate students, as well as 35 men and 27 women Royal Canadian Mounted Police (RCMP) officers, rated the abusiveness of intimate partner violence (IPV) vignettes portraying each possible gender combination of victim and perpetrator (Harris &; Cook, 1994 Harris, R. J. and Cook, C. A. 1994. Attributions about spouse abuse: It matters who the batterers and victims are. Sex Roles, 30: 553–565. [Crossref], [Web of Science ®] , [Google Scholar]). Rating differences according to victim and perpetrator gender, occupation (student or RCMP officer), and participant gender were anticipated. Analyses found that student and RCMP ratings of abuse severity were both highest for the male-female scenario. However, the RCMP considered the female-male, male-male, and female-female scenarios to be more abusive than did the students. Our findings suggest that, while the RCMP appeared to be more sensitive to male and same-sex victims than students, both groups remain somewhat biased.     

In cold blood: characteristics of criminal homicides as a function of psychopathy

This study investigated the relationship between psychopathy and the characteristics of criminal homicides committed by a sample of 125 Canadian offenders. It was hypothesized that the homicides committed by psychopathic offenders would be more likely to be primarily instrumental (i.e., associated with premeditation, motivated by an external goal, and not preceded by a potent affective reaction) or "cold-blooded" in nature, whereas homicides committed by nonpsychopaths often would be "crimes of passion" associated with a high level of impulsivity/reactivity and emotionality. The results confirmed these predictions; homicides committed by psychopathic offenders were significantly more instrumental than homicides by nonpsychopaths. Nearly all (93.3%) of the homicides by psychopaths were primarily instrumental in nature compared with 48.4% of the homicides by nonpsychopaths.     

Personality and Parenting: Exploring the Mediating Role of Transient Mood and Daily Hassles

ABSTRACT In order to explore the role that transient mood and daily hassles might play in mediating the impact of enduring personality on parenting, naturalistic home observations of mothering and fathering were conducted when firstborn sons were 15 and 21 months of age. Observationally based, behavioral ratings of mothering and fathering were related to three self-report personality scales (Agreeableness, Neuroticism, Extraversion), administered to parents when their children were 10 months of age, and to self-reports of transient mood (positive and negative) and daily hassles obtained prior to each observation of family interaction. Results indicated that (a) mothering was more consistently predicted by personality and mood/hassles than fathering; (b) Extraversion played a larger role in predicting fathering than mothering, with the reverse being true of Agreeableness; (c) Neuroticism was the most consistent predictor of men's and women's parenting; and (d) there was little support for affect-specific linkages between personality, mood/hassles, and parenting. Finally, some evidence of mediation by transient mood and daily hassles emerged, more consistently for mothers than fathers, though more strongly for fathers than mothers. These results are discussed in terms of the primacy of the role of parenting for men and women.     

Wrapping services in an urban setting

Efforts to reform services for children and their families in Baltimore City have included providing Wraparound services to youth returned or diverted from out-of-state residential treatment. We briefly present the history and evolution of the system reform efforts in Baltimore City that were necessary to support the implementation of a Wraparound model of service delivery. The characteristics of the Wraparound service model is presented along with the referral pathway of the youth into the service system, the components of the service delivery system and an overview of step-down services and linkages utilized to transition the youth. Data are presented that demonstrate the level of community adjustment of a subset of the 121 youth served through the Wraparound model in contrast to the level of community adjustment achieved by nonequivalent comparison groups. We discuss the use of report card type of outcome measures, its user-friendly features, limitations, and the developmental steps needed to refine it further.     

Visuomotor tracking abilities of speakers with apraxia of speech or conduction aphasia

This investigation examined the visuomotor tracking abilities of persons with apraxia of speech (AOS) or conduction aphasia (CA). In addition, tracking performance was correlated with perceptual judgments of speech accuracy. Five individuals with AOS and four with CA served as participants, as well as an equal number of healthy controls matched by age and gender. Participants tracked predictable (sinusoidal) and unpredictable signals using jaw and lip movements transduced with strain gauges. Tracking performance in participants with AOS was poorest for predictable signals, with decreased kinematic measures of cross-correlation and gain ratio and increased target-tracker difference. In contrast, tracking of the unpredictable signal by participants with AOS was performed as well as for other groups (e.g. participants with CA, healthy controls). Performance of the subjects with AOS on the predictable tracking task was found to strongly correlate with perceptual judgments of speech. These findings suggest that motor control capabilities are impaired in AOS, but not in CA. Results suggest that AOS has its basis in motor programming deficits, not impaired motor execution.