Cortical morphology associated with language function in neurofibromatosis,type I

Neurofibromatosis, type I (NF-I) is associated with verbal and nonverbal neuropsychological deficits and neuroanatomical anomalies. Few relationships between CNS abnormalities and cognitive function in this population, however, have been found. Reading disabilities and developmental language impairments in the general population have been associated with particular morphologic features in inferior frontal gyrus (IFG) and Heschl's gyrus (HG). We compared the morphology of these regions in children with NF-I and controls. Verbal skills in NF-I were related to IFG morphology, such that individuals with NF-I who showed "typical" gyral patterns in the right hemisphere performed worse across language measures than those showing an extra "atypical" gyrus. A doubling of HG in the left and right hemispheres was also significantly associated with performance on several neuropsychological measures. This is the first study to link regional gyral morphology with language function in NF-I. A possible molecular basis for the observed relationships is discussed.     

Using Principal Components as Auxiliary Variables in Missing Data Estimation

To deal with missing data that arise due to participant nonresponse or attrition, methodologists have recommended an “inclusive” strategy where a large set of auxiliary variables are used to inform the missing data process. In practice, the set of possible auxiliary variables is often too large. We propose using principal components analysis (PCA) to reduce the number of possible auxiliary variables to a manageable number. A series of Monte Carlo simulations compared the performance of the inclusive strategy with eight auxiliary variables (inclusive approach) to the PCA strategy using just one principal component derived from the eight original variables (PCA approach). We examined the influence of four independent variables: magnitude of correlations, rate of missing data, missing data mechanism, and sample size on parameter bias, root mean squared error, and confidence interval coverage. Results indicate that the PCA approach results in unbiased parameter estimates and potentially more accuracy than the inclusive approach. We conclude that using the PCA strategy to reduce the number of auxiliary variables is an effective and practical way to reap the benefits of the inclusive strategy in the presence of many possible auxiliary variables.     

Developmental patterns in priming and familiarity in explicit recollection

Developmental trajectories of two classes of human memory, implicit and explicit memory, appear to diverge. We examined how developmental differences in perceptual and conceptual priming, two types of implicit memory, coincide with differences between familiarity and recollective responses on explicit memory tests that employ the Remember/Know paradigm ( Tulving, 1985 ). Both types of priming were characterized by developmental invariance in 52 children and adolescents ages 8-19 years. Contrary to Komatsu, Naito, and Fuke (1996) results, few age-group differences in perceptual priming were observed following a levels-of-processing encoding manipulation. In contrast, age group differences were found for "Remember" but not "Know" responses. Neither levels of awareness nor strategies influenced priming. Adult levels of performance appear earlier in development on perceptual and conceptual priming tests compared to explicit memory tests. Similar developmental dissociations exist between explicit and implicit memory performance as between "Remember" and "Know" recollective responses.     

Harnessing growth mindsets to help individuals flourish

Psychologists are uniquely positioned to help with our collective obligation to advance scientific knowledge in ways that help individuals to flourish. Growth mindsets may offer one such tool for improving lives, yet some research questions the potential to replicate key findings. The aims in the current work are to help explain mixed results and outline ways to improve intervention impact. To reach these goals, we first offer a brief overview of the links between growth mindsets and psychological flourishing. Second, we outline key theories of causal mechanisms and summarize sources of meaningful heterogeneity in growth mindset interventions, with a focus on those designed to improve mental health. Third, we provide cautionary notes that highlight nuances of growth mindset messaging in contexts with stigmatized social identities. Fourth, to conclude, we suggest areas for future research aimed at understanding how to most powerfully harness growth mindsets to help individuals reach optimal psychological functioning.     

Childhood exposure to emotional abuse and later life stress among Kenyan women: a mediation analysis of cross-sectional data

Background and objective: We explore whether perceived stress among Kenyan mothers is predicted by childhood exposure to emotional abuse – both witnessed among parents and experienced directly. Further, we explore whether this association is mediated by social support, family functioning and polygynous marriage.

Design: We used cross-sectional data from a systematic random sample (n?=?1974) of mothers in semi-rural Kenya.

Methods: Data were collected using validated scales and trained interviewers. Analyses were conducted using bootstrapped structural equation models and fixed-effects linear regression models, controlling for age and household wealth.

Results: Reported experience of emotional abuse – both directly experienced and observed among household adults – was high in the present population (72.5% and 69%, respectively). Perceived stress among women was significantly higher if they were exposed to more emotional abuse during childhood (p?<?.001). Lower social support, worse family functioning and higher rates of polygynous marriage mediated pathways between emotional abuse exposure during childhood and adult perceived stress.

Conclusion: Future research should investigate whether social integration, identity formation and self-esteem underlie observed dynamics in sub-Saharan Africa. Efforts to promote social integration and support should target children currently experiencing emotional abuse, and may include child-targeted high quality television programing and adult-targeted media and celebrity campaigns.     

The Role of Emotional Distress Tolerance on Fear Responding in a Heights-Fearful Sample: Perceived Versus Actual Behavior

Emotional distress tolerance (EDT)—or the ability to withstand negative emotional states—is considered a transdiagnostic risk factor for psychopathology. Although EDT is theorized to play a role in anxiety development and maintenance, research aiming to delineate the relationship between anxiety and EDT is lacking. The current study tested whether self-reported EDT predicted self-reported and actual avoidance in the presence of feared stimuli using a heights-fearful sample. Moreover, the study tested whether EDT predicted other in-the-moment fear responses, such as peak anxiety, anxious cognitions, and bodily sensations. Participants (N = 128) completed questionnaires assessing fear of heights, negative affect, anxious cognitions, and bodily sensations, as well as two heights behavioral avoidance tasks (BATs). Results demonstrated that EDT did not predict actual avoidance or other in-the-moment fear responses, except for peak anxiety in one BAT. However, EDT predicted self-reported avoidance of heights beyond fear of heights and negative affect. Taken together, results suggest that perception of ability to tolerate emotional distress predicts perception of avoidance of heights, but not actual avoidance of heights or reactions to heights (with the exception of peak anxiety in one BAT). Given these findings, self-reported EDT may not adequately predict how individuals react in anxiety-provoking situations.     

Burnout and psychiatric “cases”: Early evidences of an association

This exploratory study extends the phase model of burnout in a critical direction by assessing whether individuals assigned to eight progressive phases will present escalating mental health symptoms. Despite the small convenience population (N = 161), the present affirmative results encourage early replications for three basic reasons. Thus the associations with mental health reported here are consistent with numerous other tests of the concurrent validity of the phase model. Moreover, substantial proportions of the variance are explained here by data supporting the view that the progressive phases are associated with accelerating proportions of “cases,” here defined as respondents to the General Health Questionnaire (GHQ) who report four or more non-psychotic psychiatric symptoms. The GHQ form used here is modified for U.S. contexts. In addition, this basic conclusion is reinforced in three ways: by factor analysis of GHQ items; by rejecting several variables alternative to the phases as GHQ variants; and by using canonical discriminant functions to compare phase assignments with the actual group memberships of “normals” and “cases” assigned by the GHQ.     

A growth mindset intervention to improve mental health in adolescents during COVID-19

COVID-19 poses a considerable threat to adolescent mental health. We investigated depression rates in teens from pre to post-COVID. We also explored if leveraging a growth mindset intervention (“Healthy Minds”) could improve adolescent mental health outcomes during the pandemic, especially for adolescents experiencing the most distress. In Study 1, we recruited youth from schools in a rural southern community (N = 239) and used a pre-post design. In Study 2, we recruited an online sample (N = 833) and used a longitudinal randomized control trial design to test the effectiveness of Healthy Minds. Across both studies, there is evidence of higher rates of depression in youth during COVID-19, relative to pre-pandemic numbers. In Study 1, the intervention effectively changed psychological and behavioral processes related to mental health, especially for adolescents experiencing greater COVID-19 stress. However, in Study 2, the intervention failed to impact depression rates or symptoms at follow-up.     

Intelligence profiles in children and adolescents with left temporal lobe epilepsy: relationship to language laterality

Pre- and postoperative IQ profiles were examined in children and adolescents with left temporal-lobe epilepsy. Participants were grouped according to their pattern of speech dominance, as indicated by the intracarotid sodium amobarbital procedure. Seven participants with typical (left hemisphere) speech representation were matched for age and sex to seven participants with atypical (bilateral or right hemisphere) speech representation. The group with atypical speech representation tended to perform worse pre- and postoperatively on several verbal and nonverbal subtests. Unlike Strauss et al.'s (1990) sample, however, the groups did not differ significantly on pre- or postoperative Performance IQ. The results suggest that when individuals are matched closely for age and sex, there may only be limited support for a nonverbal "crowding" hypothesis. Atypical speech representation in children and adolescents with early temporal-lobe epilepsy appears to be associated with lowered performance on both verbal and nonverbal IQ subtests.