Sample size determinations for the two rater kappa statistic

This paper gives a method for determining a sample size that will achieve a prespecified bound on confidence interval width for the interrater agreement measure,. The same results can be used when a prespecified power is desired for testing hypotheses about the value of kappa. An example from the literature is used to illustrate the methods proposed here.     

Risk perceptions and participation in colorectal cancer screening

Compared individuals at high versus average risk for colorectal cancer (CRC) with respect to factors they cited as affecting their risk of developing CRC. We also examined the relationship of these risk-factor perceptions to perceived susceptibility and participation in a CRC screening test. All individuals in the high-risk group were informed that, as a sibling of someone with CRC, they were more likely to get this cancer themselves. We found minimal differences among siblings with respect to perceived susceptibility. Further, although high-risk siblings were more likely to participate in screening, only 20.2% cited heredity as a risk-increasing factor, and, among these siblings, there was no relationship between screening participation and the citation of any specific risk factors, including heredity. These findings demonstrate the need for more research examining how high-risk individuals process risk-relevant information and the effect of this information on health behavior.     

Bullying Victimization and Use of Substances in High School: Does Religiosity Moderate the Association?

Alcohol, tobacco and other drug use continue to pose serious public health concerns among youth. Bullying victimization has been identified as a risk factor and religiosity a protective factor for adolescent substance use. No previous research has examined the potential moderating role of religiosity. We explore the association between bullying victimization and substance use in adolescents with low and high levels of religiosity. A cross-sectional survey was conducted with a representative sample of high school students in greater Beirut. Binary and multinomial logistic models were used, adjusting for demographics, and stratified by level of religiosity. Of the 986 students responding to the survey, 65% were females; 48% had experienced some form of bullying; and 52% self-rated as low in religiosity. Between 10 and 30% were current users of alcohol or tobacco. Students of lower religiosity levels who had been bullied were more likely to use substances than those who self-rated as high religiosity. Religiosity may be a potential moderator of the association between being bullied and substance use, but the exact mechanisms and underlying reasons need further investigation.

     

The impact of uncertainty and communal coping on mental health following natural disasters

Feelings of uncertainty are a central feature of the disaster experience. Surprisingly, though, there is very little systematic quantitative research about the impact of uncertainty on disaster survivors. Moreover, communal coping has increasingly received attention as a potential buffer of the negative effects of stressors but that literature is also limited in its application to disasters. This investigation applies research in the domain of uncertainty, together with the Theoretical Model of Communal Coping to better understand the experience of a community exposed to three wildfires in a one year period. A random-digit dialing procedure was used to gather data from 402 individuals. Participants completed measures of mental health, uncertainty, and communal coping in the context of their experience with the most personally stressful of the three wildfires. All analyses were examined separately for those who were evacuated and those who were not. Results support the negative impact of uncertainty across both evacuated and nonevacuated sub-samples and show a strong buffering role for communal coping among those who evacuated. The implications of these findings for the understanding of wildfire survivors' experiences are noted and future directions are proposed.     

我们应该“创造生命”吗？

人造细胞是现代生物科学技术中的热点问题之一,由人造细胞及其衍生出来人造生命的伦理问题也备受关注,关于是否应该继续研究人造生命,支持者和反对者之间各执其词。以克莱格·文特“创造人造细胞”事件为切入点,回顾了人造生命的历史,简要介绍人造细胞的产生过程,分析人造细胞的正面和负面影响;同时提出马克思主义哲学可以为医学伦理问题的研究提供不同的维度与角度,让人们对人造细胞产生的道德问题做出更全面的判断。     

Capturing Children's Response to Parental Conflict and Making Use of It

To read this article's abstract in both Spanish and Mandarin Chinese, please visit the article's full-text page on Wiley InterScience ( http://interscience.wiley.com/journal/famp ).
The aim of our study is to examine the interface between children's physiological changes and the specificities of parental conflict, and to develop a procedure in which such information can be shared with the family for therapeutic change. Children from 20 families were exposed to parental conflict discussion (CD) while their arousals were measured through skin conductance and heart rate sensors. It was found that regardless of the subject of the argument, 80% of the time they were complaining about each other. Likewise, 80% of the time the children were responding to the parents' own interpersonal tension, including moments of silence. The protocol established for the study, consisting of CD and debriefing, was found to be a powerful tool in moving parents toward conflict resolution.     

Overcoming Barriers to Collaboration Between Basic Behavioral Scientists and Public Health Scientists in Research on Mental Disorders

The behavioral and public health sciences both have a long and rich history supporting basic, translational, and applied research aimed at improving human lives and reducing human suffering. Through the complementary expertise of these disciplines, investigators have contributed to significant, worldwide improvements in mental and physical health. Further gains can be achieved through collaborative research among scientists in these 2 fields. Unfortunately, there are a number of barriers to such collaboration originating in different intellectual traditions, research methods, and the structure and values of academia. We identify these barriers and potential strategies for overcoming them. Several areas for future collaborative research appear promising, especially comorbid mental and physical disorders, adherence to interventions, stigma, and emotional processes. Theory-guided preventive interventions may represent especially fertile areas of collaborative effort.     

Mothers' Impact on Daughters' Cardiovascular Reactivity in a High‐Threat Context: An Immersive Virtual Environment Study

Applying Attachment Theory, research on confirmation, the Entropy Model of Uncertainty, and the Biopsychosocial Model of Challenge and Threat, this investigation examined the role of mothers' communication on adolescents' cardiovascular response to threat. An experimental design allowed for the manipulation of maternal response to daughters experiencing a rapidly approaching wildfire in an immersive virtual environment. Results revealed complexities in the relative benefits of maternal vocalic presence during high‐threat situation, with the mother's history of confirming feedback playing an important role in daughters' cardiovascular response. Implications for knowledge are addressed and methodological possibilities of using immersive virtual environments are noted.     

Examining predictors and consequences of information seeking in close relationships

The management of information in close relationships plays a critical role in our well‐being (e.g., S. Petronio, 2002 ). Since relational partners often desire to be “in the know” about one another, the relative absence of inquiry into the process of information seeking in close relationships is puzzling. Recently, W. Ickes, J. W. Dugosh, J. A. Simpson, and C. L. Wilson (2003) examined that process and showed important ways in which the motivation to acquire relationship‐threatening information may be harmful to relationships. We extend their work and apply the newly developed Theory of Motivated Information Management (W. A. Afifi, & Weiner, 2004 ) to close relationships. In addition, we test the consequences of information seeking for short‐term changes in relationship commitment. Two hundred and twenty‐two participants thought of something that their relational partner did or said for which they wanted more information, then completed 2 surveys, 3 weeks apart, measuring cognitive and behavioral factors related to the information‐management process. Results reveal several factors that influence the seeking of information in close relationships (e.g., issue importance, anxiety, expected outcomes, and perceived efficacy), show benefits of an indirect search for information in the face of negative expectancies, and suggest several directions for future research.     

The Role of Expectations in Effective Genetic Counseling

The goals for this investigation were to assess individuals' expectations for social support from genetic counselors, and to explore how these expectations influence perceptions of genetic counselor effectiveness. Two studies were conducted to address these goals. Results from the first study show that individuals most frequently expect genetic counselors to provide options and support following the disclosure of distressing test results, while data from the second study demonstrate that expectations play a significant role in individuals' assessment of genetic counselor effectiveness. These findings shed light on what individuals expect from genetic counselors following the disclosure of medically positive test results and inform how these expectations influence the success of genetic counseling sessions.