Attenuation of Hippocampal 11beta-Hydroxysteroid Dehydrogenase Type 1 by Chronic Psychosocial Stress in the Tree Shrew

11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) catalyses the interconversion of active cortisol and corticosterone with inert cortisone and 11-dehydrocorticosterone, thus regulating glucocorticoid access to intracellular receptors. In rats, chronic glucocorticoid excess or stress increases 11beta-HSD-1 in the hippocampus, producing suggestions that it may attenuate the deleterious effects of chronic glucocorticoid excess. However, 11beta-HSD-1 predominantly catalyses 11beta-reduction in the intact liver and hippocampal cells, thus regenerating active glucocorticoids from inert substrate. We studied 11beta-HSD activity in the tissues of male tree shrews following 28 days of sustained psychosocial stress or exogenous administration of cortisol. In the hippocampus, chronic psychosocial stress attenuated 11-HSD-1 activity (69 +/- 9% of control), whereas cortisol alone had no effect. In the liver, both chronic stress and cortisol administration decreased 11beta-HSD-1 activity (47 +/- 11% and 49 +/- 4% fall, resp.). Attenuation of 11beta-HSD-1 within tissues may reflect a homeostatic mechanism designed to minimise the adverse effects of prolonged stress and/or glucocorticoid excess.     

Effects of limited peripheral vision on shuttle sprint performance of soccer players

This study examined the effect of limited peripheral vision on the shuttle sprint performance of soccer players. Participants were 14 male soccer players of a student soccer club (M age = 22.1 yr., SD = 1.3 yr.). They performed a repeated shuttle sprint with full and limited peripheral vision. Mean total sprint time and mean turning time increased significantly with limited peripheral vision. It is concluded that only turning during shuttle sprint performance decreases when sprinting with a restricted peripheral field of view, indicating the use of peripheral vision for the control of directional changes while sprinting.     

Interval endurance capacity of talented youth soccer players

The purpose of this study, in which 113 talented youth soccer players (M = 16.0 yr., SD = 1.5), selected by their age and level of performance participated, was to investigate interval endurance capacity needed to play at the highest level of competition in the age-category 12 through 18. Multivariate analyses of covariance with factors of level of performance and age category showed that players ages 16 through 18 years outscored the players ages 12 through 15 years on the interval endurance capacity (p < .05). In both age categories, elite players outscored less skilled players (p < .05). In the age category 12-15 years, the elite players participated more in soccer training than less skilled players (p < .05), whereas less skilled players participated more in additional training than the elite players (p < .05). No differences were found for total training (p > .05). In conclusion, development of the interval endurance capacity seems crucial for a talented youth soccer player to be successful.     

Is there still a cognitive cost of being a twin in the UK?

ObjectiveTo investigate whether twins still perform below singletons in cognitive ability tests and in national educational attainment examinations in a recent UK cohort of 11-year-olds.DesignPopulation-based cohort study, using a validated method of twin extraction.SettingEnglish state schools.Participants178,599 pupils (mean age 11 years) attending English state schools in 2004, representing 93% of local educational authorities.Main outcome measuresVerbal, quantitative and nonverbal reasoning measured by the Cognitive Abilities Test — Third Edition (CAT3), and educational attainment in English, maths and science from Key Stage 2 national curriculum tests.ResultsTwin-singleton differences in cognitive ability were of negligible effect size. Mean performance of twins was 1% of a SD below singletons on general cognitive ability, 3% lower on verbal reasoning, and less than 1% of a SD lower on quantitative and nonverbal reasoning, with and without adjustment for sex. Almost identical proportions of twins and singletons attained the expected standards of educational performance in English (80.4% versus 80.5%, respectively), maths (77.4% versus 77.3%), and science (90.1% versus 88.8%). There were no differences in rates of twins and singletons achieving higher or lower performance levels.ConclusionThe cognitive cost of being a twin reported in previous cohorts of UK children no longer exists in a large, contemporary and population-representative sample.     

Normative data for a brief neuropsychological screening battery. Multicenter AIDS Cohort Study.

This study reports normative data for a group of 733 homosexual/bisexual men stratified by age (range 25 to 54 years) and by education on the following six neuropsychological tests: (1) Digit Span (WAIS-R), (2) Rey Auditory Verbal Learning Test, (3) Symbol Digit Modalities Test, (4) Controlled Oral Word Association Test, (5) Grooved Pegboard, and (6) The Trail Making Test. Analysis demonstrates that both age and education are important determinants of performance for several of these measures.     

Support Groups for Suicide Survivors: Results of a Survey of Group Leaders

To update and expand Rubey and McIntosh's (1996) survivors of suicide support groups report, SPAN USA completed a survey of U.S. support group leaders (n = 100; 24% completion). There are now more survivor groups (from 280 to 417), and the majority of groups now have a survivor leader (78% vs. 25%). Groups continue to be small (88% < 10 members per session) and meet on a monthly basis (55%). Sharing continues to be a universal experience in groups, which tend to be open‐ended (85%). Current groups are newer, and more operate without a sponsor. Further research is needed to examine group member perspectives and effectiveness of groups.     

Youth Media Lifestyles

In this article, the concept of “media lifestyles” is adopted in order to develop a comprehensive approach toward youth engagement in communication media. We explore how 503 Dutch eighth grade students with full access to new technology combine a broad range of media by focusing on their engagement with media while taking various contexts of use into account. Four different media lifestyles of media omnivores, networkers, gamers, and low‐frequency users are described. Furthermore, we show how the methodology we used is able to provide more insight into how the distinguished media lifestyles were codetermined by particular media, functions and social contexts. Finally, the implications for the Uses & Gratifications theory are discussed.     

Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932

Apolipoprotein E (APOE) genotype is a possible influence on nonpathological cognitive aging. The authors studied 462 community-dwelling, 79-year-old people born in 1921, whose childhood IQ had been assessed in the Scottish Mental Survey of 1932 (Scottish Council for Research in Education, 1933). Adjusting for sex, childhood IQ, and self-reported illnesses, the authors found that those with an APOE e4 allele had significantly lower Wechsler Logical Memory (D. Wechsler, 1987) scores than those without an e4 allele. Those people with APOE s2/e3 genotypes had significantly higher Wechsler Logical Memory scores than e3/s3, who were significantly higher than e3/e4. Neither nonverbal reasoning nor verbal fluency were affected. In this sample, APOE genotype contributed to verbal memory in old age.     

Effect of intermittent exercise on multiple-choice reaction times of soccer players

The influence of intermittent exercise on a choice-response time task was investigated. Two groups of 8 male soccer players (M age = 20.9, SD = 2.0) participated. They spent 4.4 (SD = 1.3) weekly hours on soccer training and had been playing soccer for 13 (SD = 3.3) years. Multiple-choice reaction speed and response accuracy were measured four times. Between measurements, one group performed 8-min. blocks of intermittent exercise on a bicycle ergometer and one group rested. Analysis showed that reaction speed and response accuracy were not significantly different between the two groups. Furthermore, there were significant faster reaction times and a larger number of correct reactions through Block 2 in both the exercise and control group (p < .05), probably a result of learning processes and familiarization with the task procedures. Further research towards the specific influence of mode of exercise, intensity, work-rest ratio and duration of intermittent exercise, and the sensitivity of reaction time tasks will be necessary to clarify the relationship between intermittent exercise and cognitive performance.