Limiting the role of the family in discontinuation of life sustaining treatment

In matters of discontinuation of life-sustaining treatment, traditional role of the family to speak on behalf of the incompetent patient is questionable. We explore the reasons why physicians perceive patient autonomy to be transferrable to family members. Principle of patient autonomy may not suffice when futile treatment is demanded and may serve to erode the ethical integrity of medical profession. An enhanced role for bioethics committees is proposed when physicians propose to discontinue life-sustaining treatment against the wishes of the patient or their families.     

Does Partisan Bias Modulate Neural Processing of Political Information? An Analysis of the Neural Correlates of Corruption and Positive Messages

Daily worldwide newspapers print articles exposing government corruption. Yet these messages do not lead to a loss of votes for the corrupt parties. Sympathizers’ partisan bias, which respectively minimizes and maximizes corruption and positive messages of their own parties respectively, is widely considered the main cause of the loss of effectiveness of political communications. Despite the well-established existence of such bias when processing political information, little is known as to its psychological origin. Through the use of neuroscience (fMRI), this study explores the underlying brain mechanisms of negative (corruption) and positive political messages related to a conservative and a socialist Spanish political party, as well as the differences between their sympathizers. The findings reveal that negative (vs. positive) political messages exert the greatest neuroimaging impact on the electorate, as shown in aversive, risk, and disappointment-related brain regions. Interestingly, we show that there exists a main partisan bias against opposite parties (and not a positive bias toward one’s own party) that stems from a higher risk, ambiguity, and disbelief provoked by both positive and negative information about rival parties. Furthermore, this bias was more pronounced among conservative supporters. The current findings provide valuable insights for political parties to improve their communication campaigns.     

Error monitoring dysfunction across the illness course of schizophrenia

Response monitoring abnormalities have been reported in chronic schizophrenia patients, but it is unknown whether they predate the onset of psychosis, are present in early stages of illness, or are late-developing abnormalities associated with illness progression. Response-synchronized event-related potentials (ERP) recorded during a picture-word matching task yielded error-related negativity (ERN), correct-response negativity (CRN), and error positivity (Pe) from 84 schizophrenia patients (SZ), 48 clinical high risk patients (CHR), and their age-matched healthy controls (HC; n = 110 and 88, respectively). A sub-sample of 35 early illness schizophrenia patients (ESZ) was compared to 93 age-matched HC and the CHR patients (after statistically removing the effects of normal aging). Relative to HC, 1) SZ, ESZ, and CHR had smaller ERNs, and 2) SZ and ESZ had larger CRNs and smaller Pes. Within the SZ, longer illness duration was associated with larger CRNs but was unrelated to ERN or Pe. CHR and ESZ did not differ on ERN or CRN, although Pe was smaller in ESZ than CHR. These results indicate that while ERN, CRN, and Pe abnormalities are present early in the illness, only the ERN abnormality is evident prior to psychosis onset, and only the CRN abnormality appears to worsen progressively over the illness course. Brain regions subserving response monitoring may be compromised early in the illness and possibly during its clinical prodrome.     

Cross-Cultural Evaluation of the International Affective Picture System on an Indian Sample

The International Affective Picture System (IAPS) is widely used in emotion and attention research. Currently, there is neither a standard database of affective images for use in research with Indian population nor data on the way people from India respond to emotional pictures in terms of different dimensions. In the present study, we investigated whether self-reported Indian ratings are comparable to the original normative ratings (based on a North American sample) to evaluate its usability in Indian research context. The ratings were obtained from a sample of eighty Indian participants (age range?=?18 to 29 years, M _age?=?23.7, SD?=?2.67, 45 % females) on a stratified representative sample of 100 IAPS pictures. Similar to the normative data collected from the North American sample in the original IAPS database, the ratings were collected across three dimensions – valence (how pleasant/attractive or unpleasant/aversive), arousal (how calm or excited was the intensity of activation), and dominance (how controlling). Our results indicate similarities in valence ratings, but differences in arousal and dominance ratings between the Indian and the North American samples. The relationship between arousal and valence showed a similar (but less curved) boomerang shaped distribution seen with the North American sample. Unlike the North American sample, slopes were higher and intercepts were different for the Indian sample. However, the Indian sample also showed positivity offset and negative bias like the North American sample. These affective ratings show a fair amount of similarity but care is needed especially with arousal values in using these pictures for research with Indian population. While there are subtle differences in the relationship between different affective dimensions, there are also major similarities across cultures in affective judgments.     

Smarter than we think: when our brains detect that we are biased

Human reasoning is often biased by stereotypical intuitions. The nature of such bias is not clear. Some authors claim that people are mere heuristic thinkers and are not aware that cued stereotypes might be inappropriate. Other authors claim that people always detect the conflict between their stereotypical thinking and normative reasoning, but simply fail to inhibit stereotypical thinking. Hence, it is unclear whether heuristic bias should be attributed to a lack of conflict detection or a failure of inhibition. We introduce a neuroscientific approach that bears on this issue. Participants answered a classic decision-making problem (the "lawyer-engineer" problem) while the activation of brain regions believed to be involved in conflict detection (anterior cingulate) and response inhibition (lateral prefrontal cortex) was monitored. Results showed that although the inhibition area was specifically activated when stereotypical responses were avoided, the conflict-detection area was activated even when people reasoned stereotypically. The findings suggest that people detect their bias when they give intuitive responses.     

“Now We Will Have the Dalit Perspective”

This article seeks to resolve the present impasse within Dalit theology generated by an overreliance on and undertheorizing of the question of Dalit identity. It argues that the implicit location of Dalit theology as a theology of identity does a disservice to Dalit theology itself. Rather, what is needed is to nuance the question of Dalit identity and then flesh out what we mean when we speak of “the Dalit perspective.” Key to doing this is to reconceptualize Dalit identity as a fluid identity: that is, an identity that both destabilizes and allows for the assemblage of alliances among all afflicted.