FACTORS THAT INFLUENCE DEPRESSIVE SYMPTOMS IN MOTHERS OF INFANT

This study explored the association between interpersonal factors and depressive symptoms in first-time mothers over the first two years of parenthood. An interpersonal style characterized by dependency, recollections of rejection in childhood, and current relationship characteristics was assessed in a nonclinical sample of 133 women. The final model explained 52% of the variance in depressive symptoms at 24 months. Controlling for initial symptom levels, interpersonal variables explained 24% of the outcome variance. The findings suggest that two interpersonal attributes, peer rejection in childhood and a dependent interpersonal style, are particularly important to our understanding of depressive symptomatology.     

BEHAVIORAL MOMENTUM IN THE TREATMENT OF NONCOMPLIANCE

Behavioral momentum refers to the tendency for behavior to persist following a change in environmental conditions. The greater the rate of reinforcement, the greater the behavioral momentum. The intervention for noncompliance consisted of issuing a sequence of commands with which the subject was very likely to comply (i.e., high-probability commands) immediately prior to issuing a low-probability command. In each of five experiments, the high-probability command sequence resulted in a “momentum” of compliant responding that persisted when a low-probability request was issued. Results showed the antecedent high-probability command sequence increased compliance and decreased compliance latency and task duration. “Momentum-like” effects were shown to be distinct from experimenter attention and to depend on the contiguity between the high-probability command sequence and the low-probability command.     

Functional activity in the brain of socially deprivated rats produced by an active avoidance test after razobazam (Hoe 175) treatment: a 2-deoxyglucose study

The 2-deoxyglucose (2-DG) autoradiographic method was used to map metabolic activity in the brain of socially deprivated rats during an active avoidance test. The method investigated the effects of razobazam during this learning test. The animals were socially deprivated for 5 weeks. On the first experimental day the animals were trained to avoid a footshock by jumping onto a platform. During training and testing, the total number of avoidance responses was scored. On the second day during one 2-DG session of 40 min, razobazam increased the avoidance score by 18% as compared to controls. Autoradiographs were analyzed using a two-dimensional densitometric method. The analysis of the brain structures showed a 22% reduction of optical density in the nucleus habenularis lateralis, a 25% increase in the caudal part of the nucleus accumbens, and a 13% increase in the frontal cortex in rats treated with razobazam, but no change in the amygdala. These results provide a preliminary concept to explain how the new compound razobazam produced a better learning performance in socially deprivated rats.     

The effect of phonemic processing on the retention of graphemic representations for words and nonwords

The three experiments reported in this study were each conducted in two phases. The first phase of Experiment 1 involved a same-different comparison task requiring “same” responses for both mixed-case (e.g., MAIN main) and pure-case (e.g., near near) pairs. This was followed by Phase 2, a surprise recognition test in which a graphemic effect on word retention was indicated by the superior recognition accuracy obtained for pure-case compared with mixed-case pairs. The first phases of Experiments 2 and 3 involved pronounceability and imageability judgment tasks, respectively. Graphemic retention was assessed by contrasting recognition accuracy for letter strings presented, during Phase 2, in their original Phase 1 case, with letter strings presented, during Phase 2, in. a graphemically dissimilar new case. The experiments provided evidence that there was minimal retention of the graphemic representations from which the phonemic representations of words are generated and, further, that the locus of this effect is probably postlexical. Nonwords were recognized more accurately than words in all three experiments. The latter result was attributed to differences between nonwords and words in both graphemic retention and semantic distinctiveness.     

Cholinergic system in the toad's (Bufo bufo L.) visual system

The brain structures mediating the prey-catching behavior of the toad have been described in earlier studies but none of these studies has identified the transmitter systems in the optic tectum responsible for this behavior. Behavioral tests with different test compounds provide evidence that the cells responsible for the orienting, jumping, and snapping behaviors associated with feeding in toads are normally inhibited by cholinergic synapses.     

Age differences in the temporal locus of memory organization in children's recall

Age differences in when (i.e., at input or output) children organize information for recall were investigated in terms of a model specifying that information organized at input is more resistant to forgetting over time than information not organized at input. In Experiment 1, recall of items from categorically related and unrelated lists was assessed either immediately or after a 4-min delay. For 9-year-olds, the effect of delay was comparable for the related and unrelated lists, indicative of spontaneous organization at time of output. In contrast, 13-year-olds showed a significantly smaller delay effect with related than with unrelated lists, indicative of spontaneous organization at time of input. Experiments 2 and 3 demonstrated that, for 9-year-olds, high levels of clustering in and of themselves do not eliminate effects of delayed testing characteristic of output organization, and that when 9-year-olds are biased to organize information at input, delay effects are reduced only when measures are taken to ensure that all the category labels are retrieved.     

Interaction between catecholaminergic and opioid systems in an active avoidance task

Male NMRI mice were given intravenous injections of the noradrenergic neurotoxin DSP4 or the vehicle 24 to 72 h prior behavioral testing. Animals were given 2 days of training on a one-way active avoidance task. Naloxone was given in one of three doses prior to training on Day 1 and Day 2 or prior to training on Day 1 only (saline was given prior to training on Day 2). There was a dose-dependent impairment of acquisition by naloxone in the vehicle-pretreated groups; 10 mg/kg naloxone produced a significant impairment of acquisition. Naloxone also modulated retention (Day 2) performance of the active avoidance task. For vehicle-pretreated mice, 1 mg/kg naloxone facilitated and 10 mg/kg naloxone-impaired performance on Day 2. DSP4 alone produced an impairment of acquisition of this task but had no effect on retention; Day 2 scores were slightly higher in the DSP4-pretreated group than in the vehicle-pretreated group. Naloxone produced somewhat different effects in DSP4-pretreated animals than in vehicle-pretreated animals. Naloxone (1 mg/kg) ameliorated the DSP4-induced impairment of acquisition; 10 mg/kg naloxone did not significantly alter the acquisition performance of this group. For the DSP4-pretreated mice that received naloxone before training on both days, the dose-response characteristics for retention scores were similar to those of vehicle-pretreated mice; 1 mg/kg naloxone was the facilitatory dose. However, for DSP4-treated mice that received naloxone before training on Day 1 only, there was a shift to the right in the effective facilitatory dose of naloxone. For these animals, 10 mg/kg naloxone but not 1 mg/kg naloxone significantly enhanced retention performance. We discuss these results in the context of a possible state-dependent modulation by naloxone in the DSP4-treated animals.     

Coping with threat and memory for ambiguous information: testing the repressive discontinuity hypothesis

Two studies examined the influence of coping dispositions (repression, sensitization, and nondefensiveness) and anxiety on the encoding and memory representation of ambiguous threat-related stimuli. In Study 1, memory was tested shortly after encoding. Study 2 contrasted immediate and delayed testing. Repressers showed evidence of "mixed" affective reactions to ambiguous stimuli at encoding, accompanied by weak memory representation of potentially threatening implications of these stimuli. In contrast, sensitizers and anxious individuals manifested a processing bias in favor of threatening implications of ambiguous stimuli. Influences of coping on memory were most pronounced for delayed testing. Anxiety influences on memory were weak. An expectancy-based account of individual differences in processing ambiguous stimuli is discussed.     

Detection of counter-changing contrast: second-order apparent motion without postrectification motion-energy analysis or salience mapping/feature tracking

The perception of 2nd-order, texture-contrast-defined motion was studied for apparent-motion stimuli composed of a pair of spatially displaced, simultaneously visible checkerboards. It was found that background-relative, counter-changing contrast provided the informational basis for the perception of 2nd-order apparent motion; motion began where contrast changed toward the contrast value of the background checkerboard and ended where contrast changed away from the background value. The perceived apparent motion was not attributable to either postrectification motion-energy analysis or salience-mapping/feature-tracking mechanisms. Parallel results for 1st-order, luminance-defined motion (H. S. Hock, L. A. Gilroy, & G. Harnett, 2002) suggest that counter-changing activation provides a common basis for the perception of both luminance- and texture-contrast-defined apparent motion.     

Construct validity of the Anxiety Sensitivity Index-3 in clinical samples

Using two clinical samples of patients, the presented studies examined the construct validity of the recently revised Anxiety Sensitivity Index-3 (ASI-3). Confirmatory factor analyses established a clear three-factor structure that corresponds to the postulated subdivision of the construct into correlated somatic, social, and cognitive components. Participants with different primary clinical diagnoses differed from each other on the ASI-3 subscales in theoretically meaningful ways. Specifically, the ASI-3 successfully discriminated patients with anxiety disorders from patients with nonanxiety disorders. Moreover, patients with panic disorder or agoraphobia manifested more somatic concerns than patients with other anxiety disorders and patients with nonanxiety disorders. Finally, correlations of the ASI-3 scales with other measures of clinical symptoms and negative affect substantiated convergent and discriminant validity. Substantial positive correlations were found between the ASI-3 Somatic Concerns and body vigilance, between Social Concerns and fear of negative evaluation and socially inhibited behavior, and between Cognitive Concerns and depression symptoms, anxiety, fear of negative evaluation, and subjective complaints. Moreover, Social Concerns correlated negatively with dominant and intrusive behavior. Results are discussed with respect to the contribution of the ASI-3 to the assessment of anxiety-related disorders.