An analysis of some sensitizing agents in the pathogenesis of stress-induced gastric erosive disease

Prior surgical implantation of a venous catheter sensitized rats to coldimmobilization stress. Three of six catheterized females succumbed during the stress. The remaining rats fell into two groups in terms of their core temperature at the end of the stress period: Male uncatheterized rats had higher temperatures than rats in the other three groups. No relation was found between catheter patency and magnitude of hypothermia. Degree of gastric disease paralleled the core temperature findings in that the male uncatheterized rats had significantly fewer gastric erosions than the rats in the other three groups. Additionally, a robust effect of gender was found with uncatheterized females showing more hypothermia and more gastric disease than uncatheterized males. A subsequent experiment was conducted to evaluate whether anesthesia or wearing the protective spring was responsible in part for the sensitization seen. Here, the gender difference was less although females consistently averaged lower core temperatures after stress than did males. Despite similar core temperatures after stress, females that were prepared with the protective spring apparatus developed more gastric disease than female controls or similarly treated males. Thus, the additional sensitization exhibited by females in the first experiment may relate to the fact that both catheterization and the taping procedure were sensitizers while only catheterization was a sensitizer for males.     

Does “Violent” Mean “Bad”? Individual Definitions of Violence

People use the word “violent” to describe a wide range of behaviors. When referring to acts of force, however, past research indicates that people often reserve the word “violent” to refer to acts of force that they define as “bad.” In the current study we use vignettes to explore variation in people’s definitions of a particular instance of the use of force. The findings indicate support for the idea that people reserve the word “violent” to refer to acts of force they view as “bad.” Findings indicate there is variation in perceptions of the level of violence, and whether the incident was even violent. Characteristics of the incident as well as the gender of those involved account for the majority of the variance explained.     

Effect of Age and Level of Cognitive Function on Spontaneous and Exploratory Behaviors in the Beagle Dog

Cognitively characterized young and aged beagle dogs were administered six different spontaneous behavior tests, which provided measures of locomotion, exploration, and social interaction. Consistent with our previous findings, we obtained no overall effect of age on locomotion. We did find, however, that for the aged dogs locomotion correlated with level of cognitive function, being lowest in age-unimpaired dogs and highest in impaired dogs. Exploratory behavior, as measured by response to novelty, varied with age, with young dogs scoring the highest. Young dogs spent more time with novel toys and a person, responded more to a silhouette of a dog, and interacted more with a model dog compared to aged dogs. Among the aged dogs, age-unimpaired dogs spent the greatest amount of time sitting or standing beside a person whereas age-impaired dogs spent the most time reacting to a reflection in a mirror. The age-impaired dogs show undirected, stereotypical types of behavioral patterns. These differences in activity patterns may be linked to underlying age-associated neuropathology.     

A multiple option observation system for experimental studies: MOOSES

The purpose of this article is to outline the development of the Multiple Option Observation System for Experimental Studies (MOOSES), a flexible data collection package for applied behavioral research. Several data collection options are available to users of MOOSES. Event-based recording, interaction-based recording, duration recording, and interval recording are available to the users and can be used individually or together, depending upon the research question. The collection program can incorporate any of the keys on the keyboard. Function keys on the top or side are used for toggle (duration states) type data collection. Types of analysis include frequency and duration of discrete events, frequency of general behavior states, frequency and duration of events within behavioral states, percent interval analysis, sequential analysis, and interobserver agreement. Data obtained from MOOSES is easily incorporated with other data for further statistical analysis with standard statistical packages or popular spreadsheet programs. Applications of MOOSES and its uses in social interaction research are presented. Comparisons with other similar systems are provided.     

A comparison of analysis methods to estimate contingency strength

To date, several data analysis methods have been used to estimate contingency strength, yet few studies have compared these methods directly. To compare the relative precision and sensitivity of four analysis methods (i.e., exhaustive event‐based, nonexhaustive event‐based, concurrent interval, concurrent+lag interval), we applied all methods to a simulated data set in which several response‐dependent and response‐independent schedules of reinforcement were programmed. We evaluated the degree to which contingency strength estimates produced from each method (a) corresponded with expected values for response‐dependent schedules and (b) showed sensitivity to parametric manipulations of response‐independent reinforcement. Results indicated both event‐based methods produced contingency strength estimates that aligned with expected values for response‐dependent schedules, but differed in sensitivity to response‐independent reinforcement. The precision of interval‐based methods varied by analysis method (concurrent vs. concurrent+lag) and schedule type (continuous vs. partial), and showed similar sensitivities to response‐independent reinforcement. Recommendations and considerations for measuring contingencies are identified.