Control networks and neuromodulators of early development

In adults, most cognitive and emotional self-regulation is carried out by a network of brain regions, including the anterior cingulate, insula, and areas of the basal ganglia, related to executive attention. We propose that during infancy, control systems depend primarily upon a brain network involved in orienting to sensory events that includes areas of the parietal lobe and frontal eye fields. Studies of human adults and alert monkeys have shown that the brain network involved in orienting to sensory events is moderated primarily by the nicotinic cholinergic system arising in the nucleus basalis. The executive attention network is primarily moderated by dopaminergic input from the ventral tegmental area. A change from cholinergic to dopaminergic modulation would be a consequence of this switch of control networks and may be important in understanding early development. We trace the attentional, emotional, and behavioral changes in early development related to this developmental change in regulative networks and their modulators.     

Executive attention and self-regulation in infancy

This study investigates early executive attention in infancy by studying the relations between infant sequential looking and other behaviors predictive of later self-regulation. One early marker of executive attention development is anticipatory looking, the act of looking to the location of a target prior to its appearance in that location, a process that involves endogenous control of visual orienting. Previous studies have shown that anticipatory looking is positively related to executive attention as assessed by the ability to resolve spatial conflict in 3–4-year-old children. In the current study, anticipatory looking was positively related to cautious behavioral approach in response to non-threatening novel objects in 6- and 7-month-old infants. This finding and previous findings showing the presence of error detection in infancy are consistent with the hypothesis that there is some degree of executive attention in the first year of life. Anticipatory looking was also related to the frequency of distress, to looking away from disturbing stimuli, and to some self-regulatory behaviors. These results may indicate either early attentional regulation of emotion or close relations between early developing fear and later self-regulation. Overall, the results suggest the presence of rudimentary systems of executive attention in infants and support further studies using anticipatory looking as a measure of individual differences in attention in infancy.     

Attraction, personality, and prejudice: liking none of the people most of the time

Unfavorable evaluations of others reflect both specific prejudice and generalized negativity. Study 1 examined self-reported norms and personal endorsement of prejudices to various social groups. Study 2 used judgments of overweight persons to examine links among prejudice, personality, and prosocial motives. Study 3 examined negative evaluations and social distancing during interpersonal interaction. Study 4 observed the translation of negative evaluations into overt discrimination. Study 5 experimentally manipulated the behavior of the target and observed its interactive effects with weight, personality, and prosocial motives. Results suggest that prejudice can emerge from otherwise unprejudiced persons when situations permit justification. Patterns in negative evaluations are linked distinctively to (a) the Big Five dimension of Agreeableness, (b) proximal social cognition and motives, and (c) discrimination.     

Attention genes

A major problem for developmental science is understanding how the cognitive and emotional networks important in carrying out mental processes can be related to individual differences. The last five years have seen major advances in establishing links between alleles of specific genes and the neural networks underlying aspects of attention. These findings have the potential of illuminating important aspects of normal development and its pathologies. We need to learn how genes and experience combine to influence the structure of neural networks and the efficiency with which they are exercised. Methods for addressing these issues are central to progress in the decade ahead.     

The anterior cingulate gyrus and the mechanism of self-regulation

The midfrontal cortex, and particularly the anterior cingulate gyrus, appears active in many studies of functional imaging. Various models have competed to explain the functions of the anterior cingulate in relation to its patterns of activation. We believe that the concept of self-regulation is valuable in considering the role of the cingulate. The sensitivity of the cingulate to both reward and pain, and evidence for cingulate coupling to cognitive and emotional areas during task performance, support this identification. Self-regulation is a very broad concept that does not lend itself very well to specific models or tests, but it does provide a framework for examining development. We trace the role of the midfrontal cortex in evolution and infant development. Both genes and environment influence self-regulation. The presence of both genetic and environmental effects raises the issue of their interaction, which we discuss in relation to the dopamine 4 receptor gene and parenting methods. The role of the midfrontal cortex in self-regulation allows us to consider both brain networks common to all people and network efficiency underlying individual differences in behavior. This research was supported by NIMH Grant HD5801 to Georgia State University and by a grant from the Dana Foundation for the study of the arts.     

Emotional expression in cyberspace: searching for moderators of the Pennebaker disclosure effect via e-mail.

Research has shown that writing about emotional topics can positively influence physical and mental health. The current study tested the efficacy of an e-mail-based writing treatment and shows how such an implementation can aid in the search for moderators. Participants (N = 546) were randomly assigned to either a long- or short-interval traumatic writing condition or to a nonemotional writing control condition. In contrast to previous disclosure research, participants received and submitted their writing responses via e-mail. Health outcomes were assessed weekly for 5 weeks after treatment and were reported at the conclusion of the study. Results supported the effectiveness of an e-mail-based writing treatment in producing positive health outcomes and successfully identified several moderators of the writing treatment effect. The moderators implicated varied depending on the nature of the health outcome assessment.     

Prospective associations between marital adjustment and life satisfaction

Actor and partner effects for the 2‐year longitudinal associations between marital adjustment and life satisfaction were evaluated in a population‐based sample of middle‐aged and older adults (N = 1,385 couples). Results showed that (a) higher marital adjustment at baseline predicted higher life satisfaction at follow‐up, (b) higher life satisfaction at baseline predicted higher marital adjustment at follow‐up, (c) marital adjustment more strongly predicted life satisfaction than life satisfaction predicted marital adjustment for women, and (d) higher partner marital adjustment at baseline predicted higher life satisfaction at follow‐up. Results suggest that marital adjustment and life satisfaction influence one another in a bidirectional fashion and that the direction is predominantly from marital adjustment to life satisfaction in women.     

Deciding to defect: the effects of video-game violence on cooperative behavior

This experiment examined the effect of video-game violence on cooperative decision making. Participants (N= 48) were randomly assigned to play either a violent or a nonviolent version of the video game Doom in dyads. Following the video-game task, participants were separated and given an opportunity to choose to cooperate with their partner for mutual gain, withdraw from the interaction, or exploit their partner for their own benefit. Participants in the violent condition were significantly more likely to choose to exploit their partners than participants in the nonviolent condition. These findings suggest that playing violent video games may undermine prosocial motivation and promote exploitive behavior in social interactions.     

Agreeableness, empathy, and helping: a person x situation perspective

This research program explored links among prosocial motives, empathy, and helping behavior. Preliminary work found significant relations among components of self-reported empathy and personality (N = 223). In Study 1, the authors examined the generality of prosocial behavior across situations and group memberships of victims (N = 622). In Study 2, empathic focus and the victim's outgroup status were experimentally manipulated (N = 87). Study 3 (N = 245) replicated and extended Study 2 by collecting measures of prosocial emotions before helping. In Study 4 (N = 244), empathic focus and cost of helping as predictors of helping behavior were experimentally manipulated. Overall, prosocial motivation is linked to (a) Agreeableness as a dimension of personality, (b) proximal prosocial cognition and motives, and (c) helping behavior across a range of situations and victims. In persons low in prosocial motivation, when costs of helping are high, efforts to induce empathy situationally can undermine prosocial behavior.