Update: new uses for lithium and anticonvulsants

Anticonvulsants are being used clinically as monotherapy and adjuncts in mental illnesses other than affective disorders. This review focuses on the literature for anticonvulsants and lithium in substance use disorders, anxiety disorders, and schizophrenia. Given the abuse potential and other difficulties with prescribing benzodiazepines for alcohol and benzodiazepine withdrawal, anticonvulsants have been considered as an alternative. Promising therapeutic effects have been demonstrated in many of the anxiety disorders, with the greatest number of trials and positive results in posttraumatic stress disorder. Although anticonvulsant and lithium augmentation for schizophrenia is common in practice and has been studied in double-blind, randomized, controlled trials, the sum of the evidence has been inconclusive.     

Using statistical risk information to assess oral contraceptive safety

The effect of variations in the presentation of oral contraceptive risk information on perceived safety was investigated. Four tests of the hypothesis that consumers focus on the absolute value of the numbers presented when assessing risk probabilities were performed with the following results: (1) when base rates are given, risks are perceived as less likely than when base rates are not given; (2) risks seem smaller when the information provided focuses on the number that will not die than when the number of expected deaths is presented; (3) contrary to our expectation, respondents do not focus on foreground numbers when risk was represented in an ‘X out of Y occurrences’ format; (4) respondents judged a risk of ‘4.15 times greater’ as less likely than when the information was presented as ‘415% greater risk’. We concluded that consumers convert statistical risk information into judgements about the magnitude of the number presented (small or large number) and utilize this more meaningful information when making risk judgements.     

Attributional Discrepancies and Bias in Cross-Cultural Interactions

Cross-cultural interactions are often confounded by differing interpretive frameworks through which meaning is attributed. The construction of an intercultural sensitizer revealed that the consequences of culturally mediated discrepant attributions may be confusion, misunderstanding, and conflict among interactants. Sources of attributional discrepancy and bias that contribute to failure in cross-cultural interactions are described. Critical incidents from A Navajo Intercultural Sensitizer (Salzman, 1991) are analyzed in the light of these common sources of error.