Male-related chemical cues promote sexual receptivity in the female musk shrew

The role of conspecific chemical cues in the activation of sexual behavior was investigated in the female musk shrew (Suncus murinus). In Experiment 1, virgin female musk shrews were exposed to either clean cages or cages recently vacated by an adult male. Regardless of whether the male used for the sexual behavior test was "familiar" to the female (having spent the 24 h exposure in his vacant cage) or "unfamiliar," females exposed to male-related cues received mounts from males significantly sooner than females exposed to clean cages. In Experiment 2, females housed for 24 h in a cage soiled by an adult male allowed males to mount significantly sooner than females housed in a cage soiled by a castrated male, another female, or a clean cage. These results demonstrate that chemical cues, produced exclusively by adult males, promote sexual receptivity in female musk shrews.     

Functional connectivity during working memory maintenance

Neurophysiological experiments with monkeys have demonstrated that working memory (WM) is associated with persistent neural activity in multiple brain regions, such as the prefrontal cortex (PFC), the parietal cortex, and posterior unimodal association areas. WM maintenance is believed to require the coordination of these brain regions, which do not function in isolation but, rather, interact to maintain visual percepts that are no longer present in the environment. However, single-unit physiology studies and traditional univariate analyses of functional brain imaging data cannot evaluate interactions between distant brain regions, and so evidence of regional integration during WM maintenance is largely indirect. In this study, we utilized a recently developed multivariate analysis method that allows us to explore functional connectivity between brain regions during the distinct stages of a delayed face recognition task. To characterize the neural network mediating the on-line maintenance of faces, the fusiform face area (FFA) was defined as a seed and was then used to generate whole-brain correlation maps. A random effects analysis of the correlation data revealed a network of brain regions exhibiting significant correlations with the FFA seed during the WM delay period. This maintenance network included the dorsolateral and ventrolateral PFC, the premotor cortex, the intraparietal sulcus, the caudate nucleus, the thalamus, the hippocampus, and occipitotemporal regions. These findings support the notion that the coordinated functional interaction between nodes of a widely distributed network underlies the active maintenance of a perceptual representation.     

Social variables influence female sexual behavior in the musk shrew (Suncus murinus)

The role of social variables in the mediation of sexual behavior was examined in the female musk shrew (Suncus murinus). Two social variables were manipulated: amount of reproductive experience and exposure to male-related chemical cues. Virgin females took significantly longer to achieve receptivity than did sexually experienced females. In addition, exposure to soiled bedding taken from a male's cage for 24-hr prior to testing reduced receptivity latencies in all females. Even a brief (30 min) exposure to male-related cues was effective in facilitating receptivity in virgins. The converse was noted for female aggressive behavior. Virgin females attacked more frequently than experienced females, and preexposure to male-related cues reduced aggressiveness. These findings suggest that social variables play an important role in female sexual behavior in this primitive eutherian mammal.     

Value-based modulation of memory encoding involves strategic engagement of fronto-temporal semantic processing regions

A number of prior fMRI studies have focused on the ways in which the midbrain dopaminergic reward system coactivates with hippocampus to potentiate memory for valuable items. However, another means by which people could selectively remember more valuable to-be-remembered items is to be selective in their use of effective but effortful encoding strategies. To broadly examine the neural mechanisms of value on subsequent memory, we used fMRI to assess how differences in brain activity at encoding as a function of value relate to subsequent free recall for words. Each word was preceded by an arbitrarily assigned point value, and participants went through multiple study–test cycles with feedback on their point total at the end of each list, allowing for sculpting of cognitive strategies. We examined the correlation between value-related modulation of brain activity and participants’ selectivity index, which measures how close participants were to their optimal point total, given the number of items recalled. Greater selectivity scores were associated with greater differences in the activation of semantic processing regions, including left inferior frontal gyrus and left posterior lateral temporal cortex, during the encoding of high-value words relative to low-value words. Although we also observed value-related modulation within midbrain and ventral striatal reward regions, our fronto-temporal findings suggest that strategic engagement of deep semantic processing may be an important mechanism for selectively encoding valuable items.     

Temporal aspects of female musk shrew (Suncus murinus) sexual behavior

The effects of testing condition on sexual behavior were examined in female musk shrews (Suncus murinus). Females were tested in 2 conditions, a pair test and a paced test. The pair test was similar to traditional sex test conditions in which the female and male are placed into the same chamber together until mating occurs. The paced condition allowed the female to leave the male's chamber and revisit him at will, thus "pacing" the interaction. Females displayed receptivity continuously for 14 days in both conditions. In the paced condition, females were less likely to become receptive within 30 min and mate to ejaculation. However, few additional differences were found between test conditions. Because this is the 1st experiment to use a pacing test paradigm in a species with induced ovulation, the authors speculate that the absence of pacing behavior during mating may be shown by other species that have induced ovulation.     

The role of lexical competition and acoustic-phonetic structure in lexical processing: evidence from normal subjects and aphasic patients

This study examined the effects that the acoustic-phonetic structure of a stimulus exerts on the processes by which lexical candidates compete for activation. An auditory lexical decision paradigm was used to investigate whether shortening the VOT of an initial voiceless stop consonant in a real word results in the activation of the lexical-semantic network of its voiced competitor, i.e., does acoustically modified time prime penny via dime. Results for normal subjects showed semantic priming for related pairs and mediated priming for voiced competitors, consistent with cascade models of language processing allowing for interaction between phonological and semantic levels of processing. Although Broca's aphasics showed semantic priming (dime primed penny), they failed to show priming in the context of a lexical competitor. These results are consistent with the hypothesis that these patients have a lexical processing deficit characterized by an overall reduction in lexical activation.     

Thematic roles: Core knowledge or linguistic construct?

Psychonomic Bulletin & Review - The status of thematic roles such as Agent and Patient in cognitive science is highly controversial: To some they are universal components of core knowledge, to...