Reinstatement of latent inhibition following a reminder treatment in a conditioned taste aversion paradigm.

Reminder treatments have been shown to facilitate the retrieval of a variety of conditioned responses. Whether or not similar results would occur with an experimental paradigm which involves primarily memory for a stimulus, i.e., where no particular response is specified, is unclear. Accordingly, using Sprague-Dawley rats, we employed a latent inhibition paradigm with a long (10 days) retention interval between sucrose (CS) preexposure and sucrose-illness pairing (training). The results demonstrated a loss of latent inhibition following the 10-day retention interval suggesting "forgetting" of the CS preexposure. However, placing a single reminder exposure to the CS within the preexposure-to-training interval reinstated the preexposure effect. Controls indicated that in the absence of the initial preexposure the reminder per se did not produce latent inhibition. Thus, a reminder can reinstate a stimulus attribute (flavor representation) and explicit conditioned responses.     

祖辈协同教养与幼儿错误信念理解能力的关系:亲子依恋与祖辈同住的作用

为考察祖辈协同教养与幼儿错误信念理解之间的关系以及幼儿亲子依恋的中介作用,采用方便抽样的方法,调查了某城市三所幼儿园345名小班至大班的祖辈协同教养幼儿及其家庭教养人。对幼儿使用操作任务考察错误信念理解能力,对其家庭教养人利用自陈式问卷收集家庭教养方式和亲子依恋等数据。结果显示：(1)祖辈协同教养类型显著影响幼儿的错误信念理解水平和亲子依恋,“有祖辈同住”协同教养幼儿的错误信念理解水平以及依恋的安全性均显著低于“无祖辈同住”协同教养幼儿;(2)亲子依恋在祖辈协同教养的民主信任和教养冲突两个维度与幼儿错误信念理解能力之间分别存在显著的中介作用;(3)祖辈协同教养类型在教养冲突、亲子依恋、错误信念理解能力的中介模型中起调节作用,在“有祖辈同住”条件下,协同教养冲突显著负向预测幼儿的亲子依恋安全感。     

Long-term effects of prior experience in attenuating amnesia

In Experiment I, prior experience with passive-avoidance training followed by latent extinction was given 1, 3, 5, or 15 days before criterion (re) training and an amnesic treatment. It produced nearly complete protection from retrograde amnesia at the three shorter intervals; at the longest interval, amnesia was present but less severe than in a control group without the familiarization. In Experiment II, prior experience was given 1, 5, or 15 days before a noncontingent shock and an amnesic treatment. Evidence of a reactivation of memory was obtained only at the longest interval. Thus, familiarization and reactivation seem to represent different processes. The results are interpreted as consistent with explanations stressing the disruption of retrieval in retrograde amnesia.     

从个体到集体：心理学视角下的集体记忆

基于拓展思维的社会互动主义视角, 采用流行病学研究思路, 记忆的形成与维护构成了集体记忆心理学研究的核心问题。相关研究一方面以“对话”为研究语境, 系统阐释了集体记忆形成中的社会传染、检索诱发遗忘、共享现实和网络聚合等心理机制; 另一方面, 聚焦于既存的记忆, 阐释了集体记忆有效性的心理原则, 同时, 记忆的身份关联性得到了确证。集体记忆心理学研究仍需拓展视野, 加强对文化记忆的有效性研究, 密切关注媒介技术变革引发的记忆变化, 积极推进本土化研究。     

Homeostatic disruption and memory: effect of insulin administration in rats

The present study examined the effect of insulin-induced hypoglycemia on 24-h retention of passive avoidance in rats. In the initial experiment, rats received either insulin (50 U/kg) or saline injections 30 min prior to training and testing. Impairments in retention were observed when animals were trained with insulin and tested with saline. This anterograde memory loss was attenuated, however, when insulin was administered prior to both training and testing. A subsequent experiment further explored the disruptive effect of hypoglycemia on memory. Data from this study indicated that lower doses of insulin at training (5 and 10 U/rat) yielded impairments in 24-h retention of passive avoidance. It is concluded that disruption of glucoregulation can produce state-dependent anterograde memory losses in rats. Possible implications for the effects of hypoglycemia on cognitive functioning in humans are discussed.     

Postural orientation: age-related changes in variability and time-to-boundary

The relation between age-specific postural instability and the detection of stability boundaries was examined. Balance control was investigated under different visual conditions (eyes open/closed) and postural orientations (forward/backward lean) while standing on a force platform. Dependent variables included center of pressure variability and the time-to-contact of the center of pressure with the stability boundaries around the feet (i.e., time-to-boundary). While leaning maximally, older individuals (ages 55-69) showed increased center of pressure variability compared to no lean, while younger subjects (ages 24-38) showed a decrease. These significant differences were found only in anterior-posterior direction. No significant age-specific differences were found between eyes open and eyes closed conditions. Time-to-boundary analysis revealed reduced spatio-temporal stability margins in older individuals in both anterior-posterior and medio-lateral directions. Time-to-boundary variability, however, was not significantly different between the groups in both medio-lateral and anterior-posterior direction. These results show the importance of boundary relevant center of pressure measures in the study of postural control, especially concerning the lateral instability often observed in older adults.     

Reconsolidation Reconsidered

Some of the considerations that led to a consolidation interpretation of retrograde amnesia (RA), which states that RA results from the disruption of memory processing and storage when neural activity is interrupted by a brain insult, are reviewed here. The time-dependent gradient of memory loss (i.e., new memories are more vulnerable to amnesia than old memories) that characterizes RA seemed to fit nicely with the notion of a cascade of cellular events occurring during the immediate post-acquisition period that would transform a labile representation into a more stable form (i.e., consolidate the memory). However, a variety of observations came to challenge the storage-disruption model, and among these was the finding of amnesia for old but reactivated memories. A recent study by Nader, Schafe, and LeDoux (2000) provides an important analytic extension of the work on "reconsolidation" by showing that inhibition of protein synthesis in the lateral and basal nuclei of the amygdala immediately following the reactivation of old memory will induce retrograde amnesia. We offer a retrieval-oriented conceptualization to account for the temporal gradient and the "reconsolidation" phenomena.