The symmetrical maze: An automated closed-field test series for rats

An automated “intelligence” test for rats is described. Supporting data indicate that this maze-problem series is sensitive to hypothyroidism-induced learning deficit and sex differences. Comparisons between this new problem set and the Rabinovitch-Rosvold (1951) closed-field tests are presented with respect to difficulty, internal consistency, and test-retest reliability.     

The development of beliefs about spelling and their relationship to spelling performance

This study examined relations among spelling performance and students' beliefs about spelling, including self-efficacy for spelling ability, outcome expectancy for spelling, and attributions for good spelling across grades 4, 7, and 10. Spelling self-efficacy remained relatively constant across grades. Spelling outcome expectancies for adult life and school declined across grades, as did effort and ability attributions for spelling success, with a disproportional decrease in ability attributions between grades 4 and 7. Self-efficacy was the strongest predictor of spelling performance at all grade levels; attribution for ability entered into the regression for grade 4 students, while outcome expectancies for school and writing were more important in grades 7 and 10. Cluster analyses on the grade 10 sample showed that students with high efficacy as spellers and high outcome expectancy of spelling for writing were the best spellers, with the highest performance reserved for those who attributed good spelling more to effort than ability. The impact of spelling instruction on developing beliefs is discussed.     

Alcohol dependence,beliefs and the priming effect

Twenty hospitalized alcoholics served as their own controls in a study which sought to compare psychophysiological and cognitive factors as mediating influences on the priming effect of alcohol. Ten subjects were independently assessed by a psychiatrist as being severely dependent on alcohol and ten as mildly or moderately alcohol dependent. Physiological, behavioural and subjective indices of the motivation to drink alcohol were employed 15 and 60 min after subjects had consumed beverages on four separate occasions corresponding to four priming conditions. These priming drinks contained either 60 ml vodka in heavy dilution or just tonic water, and in each of these conditions subjects were either led to believe that the beverages contained alcohol or they had no alcohol. The severely-dependent group displayed a degree of concordance between the indices of motivation to drink, and the levels of these tended to be significantly higher than in the less-dependent subjects. The results suggest that severely alcohol-dependent subjects were more disposed to drink 60 min after consuming alcoholic drinks than after soft drinks, regardless of whether they believed that the priming drinks had contained alcohol. Cognitive factors assumed greater importance for the drinking behaviour of less-dependent subjects, although there was evidence of discordance across behavioural, physiological and subjective measures for this group.     

Can alcohol reduce tension?

The Tension Reduction Hypothesis of alcohol use is examined in the light of recent criticism. Contrary to the conclusions of Cappell and Herman (1972) it is argued that the hypothesis is supported by evidence from animal research in most cases where an appropriate paradigm has been employed.     

A new group-training procedure for habituation demonstrates that presynaptic glutamate release contributes to long-term memory in Caenorhabditis elegans

In the experiments reported here we have developed a new group-training protocol for assessing long-term memory for habituation in Caenorhabditis elegans. We have replicated all of the major findings of the original single-worm protocol using the new protocol: (1) distributed training produced long-term retention of training, massed training did not; (2) distributed training at long interstimulus intervals (ISIs) produced long-term retention, short ISIs did not; and (3) long-term memory for distributed training is protein synthesis-dependent as it could be blocked by heat shock during the inter-block interval. In addition, we have shown that long-term memory for habituation is graded, depending on the number of blocks of stimuli in training. The inter-block interval must be >40 min for long-term retention of training to occur. Finally, we have tested long-term memory for habituation training in a strain of worms with a mutation in a vesicular glutamate transporter in the sensory neurons that transduce tap (eat-4). The results from these eat-4 worms indicate that glutamate release from the sensory neurons has an important role in the formation of long-term memory for habituation.     

Working Memory Demands and Semantic Sensitivity for Prose in Mild Alzheimer's Disease

The debate continues with regard to whether degradation of semantic knowledge or deficits in information processing lead to impaired memory performance in patients with Alzheimer's disease (AD). This study examined the effects of semantic content and working memory demands on the recall and recognition abilities of patients with mild AD. Nineteen patients with probable AD and 19 demographically matched normal control participants were asked to remember prose passages that varied in semantic content (high, medium, and low level of idea importance) and working memory demands (narrative and expository passages). Compared to the controls, patients with mild AD lost the ability to recall prose in a manner consistent with the semantic structure of the passages as the demands on working memory increased. Furthermore, as the demands on working memory increased, patients recognized information in a manner that suggested their initial processing was of isolated details rather than by semantic structure. This study provides support for the hypothesis that information processing deficits contribute to impaired semantic processing in patients with mild AD.