Cognitive impairment and whole brain diffusion in patients with neuromyelitis optica after acute relapse

The objective of this study investigated cognitive impairments and their correlations with fractional anisotropy (FA) and mean diffusivity (MD) in patients with neuromyelitis optica (NMO) without visible lesions on conventional brain MRI during acute relapse. Twenty one patients with NMO and 21 normal control subjects received several cognitive tests to assess cognitive function. Head diffusion tensor imaging (DTI) of all patients with NMO were collected with a 3-T MR system. Correlations of cognitive test scores and whole brain FA and MD were examined by voxel-based analysis. Region-of-interest analysis was applied to the significantly correlated regions which the most frequently appeared. We found that NMO patients without visible brain lesions had significantly impaired learning and memory, decreased information processing speed, and damaged attention compared with normal control subjects. These impaired cognitive domains were significantly correlated with FA and MD in local regions of corpus callosum, anterior cingulate and medial frontal cortex. In corpus callosum of NMO patients, mean FA was significantly lower and mean MD higher than normal control subjects. Our findings suggest that cognitive impairments in learning and memory, information processing speed and attention occur in NMO patients without visible brain lesions during acute relapse. The impairments in immediate and short-term memory in NMO patients may be due to information encoding deficits in the process of information acquisition. The corpus callosum of such patients may have local microscopic damages that play a role in cognitive impairments during acute relapse.     

情绪感染的发生机制

原始性情绪感染理论认为, 情绪感染是一个“情绪觉察-无意识模仿-生理反馈-情绪体验”的过程, 情绪感染是一个由生理诱发情绪的过程。早在1884年, 詹姆士和兰格就提出了情绪外周学说, 同样描述了从身体变化到情绪变化的关系路径, 但没有描述从刺激事件到外周身体变化的发生机制。对情绪感染的发生机制的研究能揭示这一“自下而上”的情绪产生机制。研究选取有效大学生被试62名, 参与下列研究：(1) 在眼动实验中使用情绪图片作为感官情绪信息, 以考察觉察者的情绪觉察水平。(2) 在生物反馈实验中, 使用仿真课堂教学视频作为感官情绪信息, 以考察觉察者的无意识模仿水平和生理反馈水平。使用路径分析证实了情绪感染的路径机制, 在真实情境的诱发下, 这种通过生理唤醒而诱发情绪的机制是可能的。     

New insight into Mencius’ theory of the original goodness in human nature

In Mencius’ theory of the original goodness in human nature, fate is the original source of xing (nature). Heart is the appearance of nature. There are two aspects to nature and heart: ti (form) and yong (function). From the perspective of form, nature is liangzhi (the goodness in conscience) and liangneng (the inborn ability to be good) in human beings and heart is human’s conscience and original heart. From the perspective of function, nature is the four things of benevolence, righteousness, propriety and wisdom, and heart consists in compassion, shame, respect, right and wrong. As the foundation for the theory of the original goodness in human nature, conscience and heart are a combination of human moral instinct, moral rationality and moral volition, whereas moral instinct gradually rises to moral volition and passes through moral rationality. Mencius’ theory of the original goodness in human nature is not a theory of future goodness, but a theory of original goodness.     

Special Topic: Filial Piety: The Root of Morality or the Source of Corruption?

In recent years, Liu Qingping 劉清平 has published a series of articles criticizing Confucian ethics in its modern context (see various articles by Liu), which has drawn the attention of many scholars. My friends and I have debated with him and his allies on this issue (See Guo 2002, Yang Haiwen 2002, Yang Zebo 2003, 2004a, 2004b, Ding 2003, 2005a, 2005b, Gong 2004, Guo and Gong 2004, and Wen 2005). Most of the important articles in the debate are now collected in a volume I edited, A Collection of Contentions about Confucian Ethics: Focusing on the Mutual Concealment among Family Members (Guo 2005 [ed.]). In the following, I attempt to respond to some of Liu’s criticisms of Confucian ethics.     

牟宗三先生以"自律道德"的理论诠释儒学之蠡测

Mou Zongsan uses the highest moral principle “autonomy” to interpret Confucius’ benevolence and Mencius’ “inherent benevolence and righteousness”, focuses on the self-rule of the will. It does not do any harm to Mencius’ learning, on the contrary, it is conducive to the communication between Chinese and Western philosophies. If we stick to Kant’s moral self autonomy and apply it to interpreting Zhu Xi’s moral theory, similarly we will discover the implications of Zhu Xi’s “autonomy” in his moral learning. Therefore, it is inappropriate for Mou Zongsan to say that Zhu Xi’s ethics belongs to the autonomous one. __________ Translated from Zhexue Yanjiu 哲学研究 (Philosophical Researches), 2005, (6): 33–39     

论熊十力对佛教唯识学的批评

熊十力《新唯识论》与唯识学者争论的第一个枢纽是关于“性体”之“性觉”与“性寂”的问题。在心性本净的理解上,唯识学主张自性涅槃,强调离染转依和修行工夫。熊十力抓住佛教唯识学的“性空”“寂静”做文章,以儒家的立场,强调“心性”不是“空”的,而是“实”的,不是“寂”的,而是“创”的,不是“静”的,而是“动”的,由“体”生发出“大用”,展开了“内圣外王”的系统,肯定了文化的建构。第二个枢纽是:“心体”是整全的、有机一体的,还是零碎的、拼凑集聚的;与此相关,道德理性的显发,道德意识的修养,是简易直捷、当下即是,还是繁琐复杂、委婉迂曲的?对于唯识学的繁复的“心”的分析,熊十力的评论可以说是一种创造性的误读。他的思想路数是华严与禅宗,特别是宋明儒的。熊的目的是创造“仁心本体”“体用不二”“即体即用”的哲学体系,讲主宰,讲大用,确立德性本体的至上性、唯一性、真实性、能动性、创造性,当然不便讲缘起、依他,而必须讲本有、依自。     

情绪感染问卷的中国化修订与信效度检验

该研究旨在编制情绪感染问卷并探讨问卷的信度与效度,问卷以Doherty编制的《情绪感染问卷》(the emotional contagion scale)作为蓝本,删除了不适合东方文化的项目,增加了符合中国人的情绪情境和展现情绪方式的项目,经过预测修订后,最终问卷包含5个维度25个项目,正式施测共回收747份有效问卷,并对数据进行了信效度检验。结果表明,探索性因素分析KMO为0.802,总问卷的标准化的Cronbach’sα系数为0.852,项目分析表明项目的鉴别指数D值在0.340~0.479之间,验证性因素分析具有较好的模型拟合度,问卷的重测信度与效标关联效度均达到显著水平。情绪感染问卷的信效度均达到了测量学的要求。     

On Confucian Political Philosophy and Its Theory of Justice

Traditional Confucian political culture (including its concepts, systems, practices and folk customs) has a legacy that deserves careful reconsideration today. Its theories, institutions, and practices address the source, legitimacy, division and balance, and restriction of political power. Confucian politics is a type of “moral politics” which sticks to what ought to be and what is justifiable, and holds that political power comes from Heaven, mandate of Heaven or Dao of Heaven, which implies that justification and standards rest with the people referring to scholars peasants, workers and merchants. This type of justification is rooted in the public space and the autonomous strength of the people, and it finds guidance in the involvement, supervision, and criticism of the class of scholar-bureaucrats (shi 士). In this article, Western political philosophy will be taken as a frame of reference for evaluating Confucian conception of justice as well as Confucian ideas of distribution, fairness of opportunity, caring kindness for “the least advantaged,” and institutional construction. It will argue that the leading characteristic of Confucian political theory is that of “substantive justice.”     

An exposition of Zhou Yi studies in modern Neo-Confucianism

The representatives of modern Neo-Confucianism all greatly value Yi Zhuan and regard it as one of their spiritual resources, and give their own creative interpretations and transformations. Xiong Shili’s ontological-cosmological theory takes “qian yuan” as its center; Ma Yifu has a theory of ontology-cultivation centered on “nature-principle”; Fang Dongmei has a metaphysics of production and reproduction; Mou Zongsan takes the view of “completely knowing the fathomless and understanding transformation” as a moral metaphysics; and in Tang Junyi there is a theory of the harmony of doctrines on Heaven and man in which “the knowledge of divine understanding” is its key concept. They employ modern philosophical concepts and thinking to illustrate the cosmology, ontology, theory of life, theory of human nature, theory of spiritual worlds, axiology and their connections in Zhou Yi. They affirm that the characteristics of Chinese philosophy that are different from Western philosophy consist in a naturalist view of vital life, a harmonious view of totality, an axiological view that values exist in natural universe and the world of fact, the pursuit of Good and Beauty, and intuitive experience of inner world. __________ Translated from Zhou Yi Yanjiu 周易研究 (Zhou Yi Studies), 2004 (4) by Hao Changchi     

The Values of Confucian Benevolence and the Universality of the Confucian Way of Extending Love

The spirit of Confucianism, which holds benevolence as its core value, has positive significance in the dialogue between civilizations and in the construction of global ethics. The values represented in Confucian benevolence are similar to the values in Christian Charity. Confucian values such as the doctrine of magnanimity, the idea of putting oneself in the place of another, and the Confucian way of extending love and favors, are crucial resources to hold in close connection with the relationship between human beings and nature, individuals and society, self and others, and one and oneself. The Confucian idea of “differentiated love” is a concrete and practical idea, which can be extended to be “universal love.” Furthermore, the Confucian way of extending love can also be interpreted as eco-ethical: On the one hand, Confucianism affirms the intrinsic value of the universe and calls for a universal moral concern for the ecological world; on the other hand, it recognizes a distinction between human beings and the nature, revealing an eco-ethical awareness of distinction and a consciousness of the differentiation between different ethical spheres. In extracting the instrumental value of ecological resources, Confucians never disregard the intrinsic value of animals and plants. Confucianism puts emphasis on subjectivity, especially the subjectivity of morality. Relationships between man and himself, between self and others, however, are inter-subjective. For Confucians, the universe exists and grows in the process of perfecting oneself, others, and the world. Such an understanding is of modern significance for the exchange and dialogue between civilizations, and the growth of personality and the mental regulation of gentleman today.