Weekends and holidays and acting-out behavior of developmentally delayed women: a reply to Dr. Mark Flynn.

A previous report on the effect of the day of the full moon on the acting-out behavior of 20 developmentally delayed, institutionalized women showed that on the day of the full moon there were significantly more misbehaviors than on any other day during the lunar period. The records were re-evaluated to assess the frequency of acting-out behaviors on weekends and holidays as contrasted with the balance of the month. This re-evaluation indicated there was no significant difference between the weekends and holidays and the balance of the month (t = 1.14). The results were taken as support of the previous findings that on the day of the full moon there were significantly more misbehaviors than on any other day of the lunar period.     

The Chancellor's memory: Rhetoric and truth in discursive remembering

This paper explores the notion of truthfulness in research on conversational remembering. It argues that people's accounts of past events, before they can be taken as data on the cognitive workings of memory, need to be examined as contextualized and variable productions that perform pragmatic and rhetorical work; no one version can be taken as a person's real memory. The consequences of this discourse-analytical perspective are examined first through a critical discussion of Ulric Neisser's study of John Dean's testimony to the senate ‘Watergate’ committee. The issues are then explored more deeply in an analysis of reportings of a different event, in which similar (Watergate-like) issues of memory, truth and accuracy are also at issue. It is argued that: (a) all of Neisser's three kinds of memory–verbatim, gist and ‘repisodic’–involve problematical assumptions concerning their relation to some true, original event; and (b) that Dean's accounts of his memory and his displays of memory should be approached as occasioned productions oriented pragmatically to the assignment of guilt and avoidance of scapegoating. Through an analysis of newspaper reports (based on memory) of a controversial briefing given by the then British Chancellor of the Exchequer, Nigel Lawson, we then examine: (a) how discourse about what could be used as an arbiter of truth was rhetorically organized; (b) how participants' versions of events were constructed rhetorically, as parts of arguments; (c) that both sides in the dispute maintained the coherence of their positions by a form of error accounting similar to that used by Neisser with respect to Dean. It is suggested that cognitive psychologists, whether working in the laboratory or attempting to do real-world studies of everyday remembering, need to avoid simplistic notions of true original events, and can do so by addressing the rhetorical organization of participants' memory accounts.     

Clauses and the semantic representation of words

When a sentence with more than one clause is processed, words of the first clause become less available for recall or recognition once the clause boundary has been passed. One common interpretation of this observation is that the representation of a given word shifts from a predominantly surface form (e.g., phonological or lexical) to a semantic form, after the clause boundary. Two experiments that test that interpretation are reported. In the first experiment, two-clause spoken sentences were followed by spoken word or picture probes. Pictures were intended to provide a fast semantic match to probed words, but a slow surface match. Although response times exhibited a robust main effect of the clause position of the probe, no interaction with probe type was found. Similar results were obtained in a second experiment that compared pictures with written word probes. The faster response to picture than to word probes in the second experiment indicates that subjects did not covertly name the picture, but made a semantic match (as intended). These observations suggest the following reinterpretation of earlier sentence memory experiments: Words in the most recent clause of a sentence are more available than words in an earlier clause because their semantic representations are more active, not because their surface representations are more active.     

Sensitivity to lexical denotation and connotation in brain-damaged patients: A double dissociation?

Sets of words can be grouped in terms of their denotation (cold and warm both refer literally to temperature) or in terms of their connotation (cold and warm connote remoteness and intimacy, respectively). To assess whether these two facets of meaning are dissociable, unilaterally left- and right-hemisphere-damaged patients were presented with word triads and asked to group together the two words that were closest in meaning. Right-hemisphere-damaged patients showed a preserved sensitivity to denotation, and a selective insensitivity to connotative facets of meanings. In contrast, left-hemisphere-damaged patients exhibited a preserved sensitivity to connotation as well as a selective insensitivity to denotative aspects of meanings. Inasmuch as normal control subjects displayed a flexible sensitivity to both denotative and connotative aspects of meaning, the results suggest that unilateral brain damage selectively curtails use of one or the other major aspect of word meaning.     

Effects of Acute Stress or Centrally Injected Interleukin-1beta on Neuropeptide Expression in the Immune System

Acute stress stimulates the expression and release of corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, and the pro-opiomelanocortin products beta-endorphin and ACTH from the anterior pituitary. These neuropeptides are also expressed in immune tissues, and it has been proposed that they may modulate immune responses to stress through paracrine mechanisms. We subjected rats to restraint stress or central injection of interleukin (IL)-1beta to determine whether these acute stimuli can alter the expression of neuropeptides in the spleen and thymus. Restraint stress significantly increased the contents of all these neuropeptides in thymic, but not splenic, extracts. A single icv injection of IL-1beta increased contents of CRH, AVP, ACTH and beta-endorphin in the spleens of both sham-operated and adrenalectomised (ADX) rats. IL-1beta increased thymic contents of CRH and ACTH in sham-operated rats but these increases were not observed in ADX rats. These results suggest that the effects of IL-1beta on neuropeptide expression in the spleen are independent of glucocorticoids, whereas IL-1beta stimulation of neuropeptide expression in the thymus is dependent on circulating glucocorticoids. There were significant correlations between increases in CRH, ACTH and beta-endorphin in the spleen, and between CRH and ACTH in the thymus, consistent with the suggestion that IL-1beta-induced increases in ACTH and beta-endorphin may be mediated through CRH. These results provide evidence that stressors can directly influence neuropeptide expression in immune tissues. Thus stress may influence immune functions through paracrine mechanisms involving locally synthesised neuropeptides as well as through activation of the hypothalamo-pituitary-adrenal axis.