Pursuit gain and saccadic intrusions in first-degree relatives of probands with schizophrenia

Oculomotor functioning of 26 probands with schizophrenia, 12 spectrum and 46 nonspectrum first-degree relatives, and 38 nonpsychiatric control subjects was evaluated. Spectrum relatives had more anticipatory saccades (ASs) and lower pursuit gain than nonspectrum relatives, who had more ASs and lower pursuit gain than control subjects. Probands also had lower pursuit gain than nonspectrum relatives and control subjects but did not differ from other groups on AS frequency. Control subjects had more globally accurate pursuit tracking (root mean square [RMS] error deviation) than both relative groups, whereas probands had the poorest RMS scores. Square wave jerk frequency did not differentiate the groups. Attention enhancement affected the frequency of ASs but did not affect either the other intrusive saccadic event or RMS scores. These results offer evidence that eye-movement dysfunction may serve as a biological marker for schizophrenia.     

Spatial compatibility of signal-response position in pointing

Two experiments are reported in which, by means of a pointing task, we studied the stimulus-position effect, i.e. the inverted U-shape form of the reaction-time function in relation to stimulus position in tasks in which stimuli and/or responses are arranged in a horizontal array. The response consisted of aiming the index finger from a central starting point at a target area on a screen. Reaction time was the main dependent variable. The spatial relation between the position of the imperative signal and the position of the response was manipulated by varying the spatial S-R compatibility and physical distance that separated the positions of stimulus and response. The stimulus-position effect was shown to depend on the compatibility of the S-R relation (Exp. 1). In Exp. 2 it was found that the modulation of the stimulus-position effect by spatial compatibility disappeared completely when the distance between the positions of stimulus and response was reduced. None of the experiments revealed that the stimulus position effect depended on signal discriminability, which renders an interpretation of this effect in terms of perceptual processes unlikely. We argue that the attentional model of spatial coding provides the most reasonable explanation of the obtained reaction-time patterns.     

Partner influences on sex-associated spoken language of children

Sex-associated features of spoken language were studied in 24 normal White middle-class children ages 4, 8, and 12 years. One hundred utterance units for each subject in conversations of same-sex and mixed-sex dyads of peers were recorded and transcribed. In same-sex dyads, boys talked significantly more about sports and location; girls referred significantly more to school, identity, and wishing and needing. In mixed-sex dyads, girls laughed significantly more, and were significantly more verbally compliant. Boys used significantly more direct requests and sound effects, and talked significantly more about sports in this situation. Major conclusions were that sex of speaker and sex of dyadic partner influence the spoken language of children.This article is based on the author's doctoral dissertation at Teachers College, Columbia University. Special thanks are extended to the dissertation sponsor, Edward Mysak, and committee members, Lois Bloom and Mary Parlee, for their generous guidance and support. Appreciation is also expressed to Mark Kesselman, Owen Whitby, Eleanor Morrison, Chester Mazur, Charles Elliott, Fred Maulucci, and Anthony Robinson for their suggestions and participation. Portions of this paper were presented at the Ninth World Congress of Sociology, Uppsala, Sweden, August 1978.     

Perinatal positive parenting: A follow-up evaluation

In an earlier article (Boger, Richter, & Weatherston, 1983) the Perinatal Positive Parenting Program (PPP) was outlined. The basic tenets of the PPP program were discussed, and an overview of the in-hospital, at-home, and parents' support group components was provided. This article presents the results of a 15-month follow-up evaluation of treatment and control participants in the initial PPP demonstration.     

Extending the search for folk personality constructs: the dimensionality of the personality-relevant proverb domain

College students (95 men and 264 women) rated how well 211 familiar proverbs described their behavior and beliefs. A factor analysis of these data yielded 7 major dimensions; many of the factors were similar to recognized lexical personality factors. Big Five Conscientiousness and Neuroticism were each strongly associated with a single proverb dimension (interpreted as Restraint and Enjoys Life, respectively). Big Five Agreeableness, Extraversion, and Intellect/Imagination were all associated with several proverb dimensions. Agreeableness was most strongly associated with proverb dimensions representing Machiavellian behavior and strong Group Ties, and both Extraversion and Intellect showed particularly notable associations with an Achievement Striving dimension. The 2 remaining proverb dimensions, which represented a belief that Life is Fair and an attitude of Cynicism, could not be accounted for by the Big Five.     

Nonconscious influence of masked stimuli on response selection is limited to concrete stimulus-response associations

A pattern-masked arrow negatively biased the "free choice" between 2 manual responses or between 2 vocal responses. This apparently nonconscious influence occurred only when the free-choice trials were intermixed randomly with other trials that terminated in fully visible arrows, which directed a response of the same modality (manual vs. vocal) as that involved in the free-choice test trials. This indicates that recent conscious processing of the association between specific stimuli and specific responses is needed to activate the nonconscious influence of masked arrows on response selection. Because this influence occurred only when a concrete association was activated, it appears not to be based on deep comprehension of the stimuli and instead is attributable to simple stimulus-response bonds.     

Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology

There is evidence that disturbances in central serotonin (5-HT) function have a role in impulsive aggression, violence, and criminality. A deletion/insertion polymorphism within the 5-HT transporter (5-HTT) promoter gene (5-HTT gene-linked polymorphic region, 5-HTTLPR) is thought to be associated with several psychopathological phenotypes related to disturbed impulse control, anxiety and depression. This study examined the association of the 5-HTTLPR with violent behavior in a sample of 153 male Caucasians referred for a forensic psychiatric examination. We found a significant excess of the short (s) allele and the s/s genotype in patients characterized by recurrent and overt physical violent behavior. This genetic variance explained 5% of the variance of violent behavior. When controlled for the impact of several psychopathologies related to violent behavior, this association was observed in individuals with a history of childhood attention deficit/hyperactivity disorder (ADHD)-related symptoms, but not presenting with personality disorder or increased impulsiveness. In conclusion, the results (i). suggest an association between serotonergic dysfunction and violent behavior, (ii). provide evidence for an-at least partial-genetic regulation of violent behavior in a subgroup of male offenders, and (iii). suggest a significant role for 5-HT transporter functionality for violent behavior.     

The impact of semantic transparency of morphologically complex words on picture naming

We examined the contribution of semantic similarity to morphological priming effects, using the immediate (Exp. 1 and 3) and the delayed variant (Exp. 2) of picture-word interference. Distractor words were either compounds morphologically related to the picture name, but differing with respect to their semantic transparency (hummingbird, jailbird (Exp. 1); butterfly, butter dish (Exp. 3)), or form-related non-compound words (e.g., trombone). All three experiments revealed strong facilitation of picture naming due to morphologically related distractors. Form-related distractors facilitated picture naming in the immediate variant only, and to a lesser degree than compounds. Interestingly, the size of the morphemic effect was almost identical for semantically transparent and opaque complex words, which suggests that they share morphemic representations. These results suggest that morphological complexity in speech production is coded at the level of form representations, independent of semantic transparency.     

Countermanding saccades: evidence against independent processing of go and stop signals

In a stop signal paradigm, subjects were instructed to make a saccade to a visual target appearing left or right of the fixation point. In 25% of the trials, an auditory stop signal was presented after a variable delay that required the subject to inhibit the saccade. Observed saccadic response times in stop failure trials were longer than predicted by Logan and Cowan's (1984) race model. Saccadic response time and amplitude decreased with the time between stop signal presentation and saccade execution, suggesting an inhibitory effect between the stop signal and the go signal processes that is not compatible with an independent race assumption. Moreover, countermanding a saccade was more difficult when stop and go signals appeared at the same location.