Results of neurophysiologic studies in ophthalmic migraine

The influence in 8 of our patients with ophthalmic migraine of photic driving with sine-like flashing lights on EEG background activity was checked and the visually evoked potentials following the application of diffused simple light stimuli were analyzed using the recovery cycle technique. The results indicate a slightly increased tonic activity of the structures of the mesencephalic formatio reticularis, such as may be produced by slight functional disturbances. Some vegetative secondary symptoms of migraine attacks and some of the changes in EEG observed in patients with ophthalmic migraine are explicable by such an abnormality.     

Three forms of stress in Cambodian adolescent refugees

Sixty-nine Cambodian adolescents and young adults were interviewed to determine their experience as children surviving the Pol Pot regime (1975–1979);their first-year experience of resettlement in this country; and their experience of stressful events during the past year. Current DSM-III-R diagnostic status was also determined. A strong relationship between earlier war trauma, resettlement strain, and symptoms of posttraumatic stress disorder (PTSD) was found. In contrast, the strongest relationship with depressive symptoms was found for recent stressful events. These results are discussed in light of current findings from stress and PTSD research.Dr. Clarke is Assistant Professor of Psychiatry in the Division of Child Psychiatry, Oregon Health Sciences University, Portland, Oregon. Dr. Sack is Director of the Division of Child Psychiatry and Principal Investigator of the Khmer Adolescent Project. Brian Goff is a Research Assistant.This project was supported by the National Institutes of Mental Health [NIMH] grant #5-RO1-MH42927-02, Dr. William H. Sack, M.D., Principal Investigator.     

What clocks tell us about the neural correlates of spatial imagery

We review a series of experimental studies aimed at answering some critical questions about the neural basis of spatial imagery. Our group used functional magnetic resonance imaging (fMRI) to explore the neural correlates of an online behaviourally controlled spatial imagery task without need for visual presentation—the mental clock task. Subjects are asked to imagine pairs of times that are presented acoustically and to judge at which of the two times the clock hands form the greater angle. The cortical activation elicited by this task was contrasted with that obtained during other visual, perceptual, verbal, and spatial imagery tasks in several block design studies. Moreover, our group performed an event‐related fMRI study on the clock task to investigate the representation of component cognitive processes in spatial imagery. The bulk of our findings demonstrates that cortical areas in the posterior parietal cortex (PPC), along the intraparietal sulcus, are robustly involved in spatial mental imagery and in other tasks requiring spatial transformations. PPC is bilaterally involved in different kinds of spatial judgement. Yet the degree to which right and left PPC are activated in different tasks is a function of task requirements. From event‐related fMRI data we obtained evidence that left and right PPC are activated asynchronously during the clock task and this could reflect their different functional role in subserving cognitive components of visuospatial imagery.     

Results of electroencephalographic and familial studies in Wilson's disease]

The results of electroencephalographic and familial studies of 31 Wilson's disease patients coming from 26 kindreds are presented. Prior to treatment, 8 patients showed pathological conditions, while 9 and 11 patients showed borderline and normal conditions, respectively, it having not been possible to determine electroencephalographic conditions characteristic of Wilson's disease and find any relationships between the intensity of E.E.G. changes and the clinical picture and stage of development of the disease, respectively. Under penicillamine treatment, there was observed a tendency toward normalization of pathological conditions rather than deterioration of normal E.E.G. findings. So far as familial studies are concerned, the authors report the results obtained for 9 fathers, 19 mothers, and 24 siblings from a total of 21 kindreds; what is remarkable in this connection is the comparatively small percentage of normal E.E.G. findings for healthy siblings. It was only in one single kindred that it was possible to observe similarities between E.E.G. variations of individual family members.     

Body-Region-Specific Injuries as Predictors of Psychosocial Outcomes Among Those Injured in Combat: Results From the Wounded Warrior Recovery Project

Associations between body region injured and psychosocial outcomes may have implications for injury prevention and mitigation strategies. The present study investigated the association of body-region—specific injuries and their association with 3 psychosocial outcomes (i.e., quality of life, QOL; posttraumatic stress disorder, PTSD; and depression) among a large sample of U.S. military service members injured in combat. A total of 1,011 individuals wounded in combat enrolled in the Wounded Warrior Recovery Project and provided QOL, depression, and PTSD measures on a Web-based survey. These psychosocial variables were linked with the presence/absence of combat injuries in 9 different body regions (head, face, neck, thorax, spine, abdomen, upper extremity, lower extremity, and external skin/other), as well as overall injury severity and demographic factors. Two-step hierarchical linear regressions revealed that after adjusting for overall injury severity and time since injury, those with combat-related head and spine injuries were particularly at risk for relatively worse psychosocial outcomes. Head and spinal injuries were associated with lower QOL and higher PTSD and depression. Overall, even those with relatively minor injuries may be at risk of lower QOL and adverse psychosocial outcomes. These findings may highlight the need for early interventions to minimize the psychological effects of combat injuries to the head and spine.     

Antecedents of entitativity in categorically and dynamically construed groups

The extent to which a set of people is perceived as a meaningful group, as one entity, is called entitativity. In this paper, we propose that there are two qualitatively different group construals, or ways of thinking, about groups: as dynamic groups or as categorical groups. Two experiments investigated this distinction. An analogy was used to induce these construals by having participants think of the same group (the group “bees”) either dynamically (as the interacting members of a hive) or categorically (as the members of the species). We then gave participants information about a social group and assessed the impact of the construal manipulation on how that information was processed. Study 1 showed that perceivers recall and report different perceptual cues (similarity and interaction characteristics, respectively) when groups are thought of in these different ways. Study 2 showed that judgments of entitativity are differentially based on a group's similarity versus interaction under these different group construals. The results suggest that group construals change the properties on which entitativity is based. Copyright © 2008 John Wiley & Sons, Ltd.     

Extending probabilistic dynamic epistemic logic

This paper aims to extend in two directions the probabilistic dynamic epistemic logic provided in Kooi’s paper (J Logic Lang Inform 12(4):381–408, 2003) and to relate these extensions to ones made in van Benthem et al. (Proceedings of LOFT’06. Liverpool, 2006). Kooi’s probabilistic dynamic epistemic logic adds to probabilistic epistemic logic sentences that express consequences of public announcements. The paper (van Benthem et al., Proceedings of LOFT’06. Liverpool, 2006) extends (Kooi, J Logic Lang Inform 12(4):381–408, 2003) to using action models, but in both papers, the probabilities are discrete, and are defined on trivial σ-algebras over finite sample spaces. The first extension offered in this paper is to add a previous-time operator to a probabilistic dynamic epistemic logic similar to Kooi’s in (J Logic Lang Inform 12(4):381–408, 2003). The other is to involve non-trivial σ-algebras and continuous probabilities in probabilistic dynamic epistemic logic.