Temperament and Social-Emotional Difficulties: The Dark Side of Learning Disabilities

The authors compared the relations between general psychological difficulties and dimensions of temperament in children with and without learning disability (LD). The main aim was to analyze whether and to what extent children's temperament dimensions contribute to their general psychological difficulties when LD diagnosis, age, and gender are taken into account. Participants were 52 elementary school children 7–11 years old (M age = 8.61 years, SD = 1.21 years). Twenty-six of them had been diagnosed with LD. Six teachers rated their pupils with and without LD in relation to their general psychological difficulties (Strengths and Difficulties Questionnaire) and temperament dimensions (Italian Questionnaires of Temperament). In children with LD, the main dimensions of temperament with the power to predict general psychological difficulties (i.e., emotionality and social orientation) concern these students' relationships with others (teachers and peers). The findings of the current study draw educators' and practitioners' attention to the fact that children's temperamental characteristics may affect how they experience their LD, with significant implications for their later social adjustment.     

Spanish adaptation of the Adolescents' perceived collective family efficacy scale

The aim of current article was the adaptation and validation of the Adolescents' Perceived Collective Family Efficacy Scale (EFCP/A) in the Spanish context. The sample includes 486 adolescents. Psychometric properties of the EFCP/A were examined with exploratory factor analysis, item analysis and reliability. Construct validity was examined by means of correlations with parental relationships (PBI). The correlations with drug use (tobacco, alcohol, cannabis) and coping strategies were also examined. Results supported the unidimensionality and reliability of the EFCP/A scale in the Spanish context. As hypothesised, adolescents' beliefs in collective family efficacy are highly correlated with the quality of their paternal and maternal relationships. Further, the adolescents who are convinced that their family is efficacious display more productive coping strategies and less drug use.     

The role of protein synthesis in memory consolidation: progress amid decades of debate

A major component of consolidation theory holds that protein synthesis is required to produce the synaptic modification needed for long-term memory storage. Protein synthesis inhibitors have played a pivotal role in the development of this theory. However, these commonly used drugs have unintended effects that have prompted some to reevaluate the role of protein synthesis in memory consolidation. Here we review the role of protein synthesis in memory formation as proposed by consolidation theory calling special attention to the controversy involving the non-specific effects of a group of protein synthesis inhibitors commonly used to study memory formation in vivo. We argue that molecular and genetic approaches that were subsequently applied to the problem of memory formation confirm the results of less selective pharmacological studies. Thus, to a certain extent, the debate over the role of protein synthesis in memory based on interpretational difficulties inherent to the use of protein synthesis inhibitors may be somewhat moot. We conclude by presenting avenues of research we believe will best provide answers to both long-standing and more recent questions facing field of learning and memory.     

Hemispheric asymmetry in the processing of high and low spatial frequencies: a facial recognition task

The research investigated the relationship between spatial frequency and visual field in a facial recognition task. Faces of neutral affect (Ekman, 1979) were tachistoscopically presented to the right or left visual field. The faces were presented alone, or masked with square wave gratings of 1, 24, or 48 cycles/degree, for a duration of 10 msec. Accuracy in recognizing each target face from a group of five served as the dependent measure. Subjects were 15 males and 15 females. ANOVA results included a frequency x visual field interaction effect (p less than .001). As was hypothesized, LVF errors were highest in the absence of low spatial frequencies, while RVF errors were highest when a higher range of spatial frequencies was removed. These results confirm that the hemispheres show a differential efficiency in processing high and low spatial frequency information in faces. They also offer empirical evidence to support the clinical findings that both hemispheres contribute to facial recognition.     

Dynamic shifts in corticostriatal expression patterns of the immediate early genes Homer 1a and Zif268 during early and late phases of instrumental training

Adaptive motor actions require prior knowledge of instrumental contingencies. With practice, these actions can become highly automatic in nature. However, the molecular and anatomical substrates mediating these related forms of learning are not understood. In the present study, we used in situ hybridization to measure the mRNA levels of two immediate early genes (IEGs) in an instrumental paradigm where rats learned to lever-press for food. We report that after three training sessions, Homer 1a and Zif268 (an effector and regulatory IEG, respectively) were significantly induced within an extensive corticostriatal network relative to untrained controls. With extended training (23 sessions), however, a shift in the expression patterns of the two genes was evident. Expression of Homer 1a (official symbol Homer1) decreased significantly in frontal and cingulate cortices, whereas striatal expression was generally maintained. Interestingly, Homer 1a expression markedly increased with extensive training in the ventrolateral region of the striatum (VLS) relative to early learners, suggesting that plasticity in the VLS is required for the efficient production of the learned behavior or in habit formation. Zif268 (official symbol Egr1) expression generally decreased with extensive training; however, these changes were not significant. These results demonstrate for the first time, on a molecular level, a dynamic shift in the contribution of corticostriatal systems mediating the early acquisition and consolidation of goal-directed responses to those engaged after extensive training.     

AMPA/kainate, NMDA, and dopamine D1 receptor function in the nucleus accumbens core: a context-limited role in the encoding and consolidation of instrumental memory

Neural integration of glutamate- and dopamine-coded signals within the nucleus accumbens (NAc) is a fundamental process governing cellular plasticity underlying reward-related learning. Intra-NAc core blockade of NMDA or D1 receptors in rats impairs instrumental learning (lever-pressing for sugar pellets), but it is not known during which phase of learning (acquisition or consolidation) these receptors are recruited, nor is it known what role AMPA/kainate receptors have in these processes. Here we show that pre-trial intra-NAc core administration of the NMDA, AMPA/KA, and D1 receptor antagonists AP-5 (1 microg/0.5 microL), LY293558 (0.01 or 0.1 microg/0.5 microL), and SCH23390 (1 microg/0.5 microL), respectively, impaired acquisition of a lever-pressing response, whereas post-trial administration left memory consolidation unaffected. An analysis of the microstructure of behavior while rats were under the influence of these drugs revealed that glutamatergic and dopaminergic signals contribute differentially to critical aspects of the initial, randomly emitted behaviors that enable reinforcement learning. Thus, glutamate and dopamine receptors are activated in a time-limited fashion-only being required while the animals are actively engaged in the learning context.     

Correction to: Child Psychological Adjustment to War and Displacement: A Discriminant Analysis of Resilience and Trauma in Syrian Refugee Children

Journal of Child and Family Studies -